Center for Shock, Trauma and Anesthesiology Research (STAR)

Leadership

Chao_Wei

Wei Chao, MD, PhD
Anesthesiology Endowed Professor in Translational Research
Vice Chair for Research, Department of Anesthesiology
Co-Director, Center for Shock, Trauma and Anesthesiology Research (STAR) 
wchao@som.umaryland.edu
410-328-2660

Research Interests

My laboratory is a part of the Anesthesiology Translational Research Program (PIs: Wei Chao, Lin Zou, Brittney Williams). Funded by NIH for more than 20 years and DoD since 2017, we investigate the molecular and cellular mechanisms of sepsis, traumatic injury, and ischemic myocardial injury. We are particularly interested in the role of novel innate immune signaling in the pathogenesis of these critical illnesses. For these basic and translational studies, we use a combination of mouse genetics (transgenics and knockouts), physiology, biochemistry, immunology, and pharmacology. We are also interested in identifying novel prognostic biomarkers in sepsis and trauma. The clinical studies involve a multi-disciplinary team with complementary expertise in multi-omics, bioinformatics, statistical modeling, machine-learning, animal models, and clinical investigation in several medical centers across the U.S.A.


Rosemary Kozar, MD, PhD

Rosemary Kozar, MD
Co-Director, STAR ORC
Professor of Surgery
Director of Translational Research Shock Trauma
rkozar@som.umaryland.edu
410-328-7611

Research Interests

My areas of active laboratory research focus on endothelial dysfunction and therapeutics to mitigate shock-induced endotheliopathy and coagulopathy. We conduct human studies, utilize animal models of hemorrhagic shock, and employ a variety of in-vitro studies to examine the responsible mechanisms and identify potential targets for treatment.


Sam Galvagno, Jr.

Samuel M. Galvagno, DO, PhD, MBA, FCCM
Interim Chair, Department of Anesthesiology
Professor with Tenure
Department of Anesthesiology
sgalvagno@som.umaryland.edu
410-328-9837

Research Interests

The primary goal of my research is to coordinate, develop, and lead efforts to advance the science of aeromedical critical care, combining regional applications with a global perspective, through the cultivation of a versatile and robust research methodology. I have secondary research interests in critical care regionalization/organization, patient safety, trauma anesthesiology, and advanced monitoring for the critically ill. My clinical work in the areas of emergency medicine, anesthesiology, and critical care medicine has helped me develop several hypotheses. In both civilian and military settings worldwide, aeromedical transport has been understood as an integral component of trauma systems, but the evidence for how to best use this expensive and limited resource is often lacking. Prior work has resulted in multiple landmark publications, resulting in the highest secondary co-citation count in the world in the area of helicopter emergency medical services systems research (Peng C et al, Medicine 2022).


Thomas Scalea, MD
R Adams Cowley, Shock and Trauma, University of Maryland School of Medicine
The Honorable Francis X. Kelly Distinguished Professor of Trauma Surgery
Physician-in-Chief, Shock Trauma Center
System Chief for Critical Care Services
tscalea@som.umaryland.edu
410-328-8976

Research Interests

Dr. Scalea’s research interests include damage control, operative approaches to trauma, complex liver injuries and REBOA.

Faculty

Collaborators

Administrative Team

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