Agenda

May 17, 2024

All sessions are located in HSRF III, Room 1010.
Registration, breakfast, coffee breaks, the poster session, and networking event will be held in HSRF III Atrium.

Program at a Glance

7:30 to 8:00 am

Registration & Breakfast (HSF III Atrium)

8:00-8:10 am

Opening Remarks -- USM Chancellor Jay A. Perman, MD

8:10 to 8:50 am | Keynote Lecture

"Winding pathways driving normal hematopoietic stem-progenitors and leukemias"

Presented by:

Curt I. Civin, MD
Philip A. Zaffere Distinguished Professor of Regenerative Medicine
University of Maryland School of Medicine

8:50-9:00 am

Discussion

9:00-10:20am

Stem Cell Biology and Engineering (Session Chair: Elias Zambidis)

9:00-9:20 Ludovic Zimmerlin, JHU: "PARP-regulated proteogenomic reprogramming to a human 8-Cell (8C) blastomere-like stem cell state"
9:20-9:35 Zanshe Thompson, JHU: "The role of Hmga1 chromatin regulators in clonal hematopoiesis and cardiovascular disease"
9:35-9:50 Shunyao Lei, JHU: "A transcriptional enhancer regulates cardiac maturation"
9:50-10:05 Neelima Thottappillil, JHU: "Integrated transcriptomic profiling of human blood vessels defines a spatially regulated niche for perivascular progenitor cells"
10:05-10:20 Abdallah Salemdawod, UMB: "CRISPR/Cas9-based base editing of tuberous sclerosis complex gene 2: novel diagnostic tool and potential curative application"

10:20-10:35 Coffee Break

10:35-11:55 Mesodermal Lineage Cells (Session Chair: Ivy Dick)

10:35-10.55 Michal Zalzman, UMB: "DeepFreeze-3D biofabrication: creating stem-cell-laden large-scale human tissue mimetics"
10:55-11:10 Ridzky Yuda, JHU: "Chronic alcohol exposures induce myeloid-biased hematopoiesis that is perpetuated by aging"
11:10-11:25 Rahila Khuroo, JHU: "Adoptive transfer of immature myeloid cells lacking NF-kB p50 or both p50 and STAT6 as immunotherapy against murine pancreatic cancer"
11:25-11:40 Muhammad Ali, JHU: "Examining the efficacy of human iPSC-derived corneal endothelial cell injection as an alternative to pediatric endothelial keratoplasty"
11:40-11:55 Dharmendra Soni, USU: "Modulation of rescue‐competent microRNAs in cystic fibrosis lungs"

11:55-12:55 Poster Presentations and Lunch (Atrium); Sponsor Talks

Sponsor Talks

12:30-12:40 "The Digitalization of Stem Cell Research: It Begins in Academia" Patrick Dentinger, CEO, CellPort Software (HSRF III, Room 1010)

12:40-12:50 "Speed Dating with the QIAcuity Digital PCR System" Danielle Kobi, Business Development Manager, QIAGEN (HSRF III, Room 1010)

12:55-2:15 Neuroscience (Session Chair: Marta Lipinski)

12:55-1:15 Lena Smirnova, JHU: "Brain microphysiological systems for neurological disease modeling on the level of cognition"
1:15-1:30 Manoj Kumar, UMB: "Mutant GBA1 microglia induce alpha-synuclein aggregation in dopamine neurons from GBA1/PD patients"
1:30-1:45 Safiya Aafren, JHU: "Hybrid extracellular vesicles for intracerebral hemorrhage theranostics"
1:45-2:00 Whitney Sambhariya, JHU: "PTEN knockout improves survival of transplanted human retinal ganglion cells"
2:00- 2:15 Weifeng Li, JHU: "Fast generation of PDGFRA-positive oligodendrocyte progenitor cells from human embryonic stem cells by SOX9 overexpression"

2:15-2:30 Coffee Break

2:30-3:50 Disease Modeling and Applications (Session Chair: Ricardo Feldman)

2:30-2:50 Raphael Meier, UMB "Mesenchymal stem cells with enhanced MMP-9 secretion for the treatment of liver fibrosis"
2:50-3:05 Cristina Zivko, JHU: "Diverse drug response in iPSC-derived organoids and distinctive proteomic profiling for patient stratification in Alzheimer’s disease"
3:05-3:20 Olivia Sniezek-Carney, JHU: "From muscle to brain: developing stem cell models to uncover novel tissue-specific pathologies in Barth syndrome"
3:20-3:35 Xiao Liu, UMB: "Intranasal and intracerebroventricular administrated metabolic glycoengineered NSCs improved functional outcomes after cardiac arrest"
3:35-3:50 Eman Mirdamadi, UMCP: "3D printing polycaprolactone allograft bone constructs with slow releasing osteoinductive nanogels"

3:50-4:05 pm

Stem Cells Highlights from Symposium and the World Shreyas Kuddannaya

4:05-4:25 pm

Systems Biology of Stem Cell Regulation Daniel Lobo, UMBC

4:25-4:45pm

MSCRF Funding Opportunities (including discussion) Ruchika Nijhara, PhD, MSCRF Executive Director

4:45-5:00

Closing Ceremony and Awards -- Miroslaw Janowski and Maryland State Delegate Catherine M. Forbes