Robert A. Pascal Professor of Orthopaedics
December 9, 2024
Joseph P. Stains, PhD
About Joseph P. Stains, PhD
Joseph P. Stains, PhD, is a Professor in the Department of Orthopaedics with a secondary appointment in the Department of Physiology at the University of Maryland School of Medicine. He also has membership in the University of Maryland School of Medicine Center for Research on Aging, Center for Stem Cell Biology and Regenerative Medicine, and Center for Research on Biomedical Engineering and Technology.
Dr. Stains' lab examines signaling and gene transcription in cells of the skeletal system, and how signaling networks affect osteogenic differentiation, bone formation and bone quality. Using a molecular level perspective, the lab examines cell-to-cell communication among bone cells and how intercellular communication coordinate new bone remodeling and repair. Additionally, the lab examines the role of the cytoskeleton in mechanical load induced signaling in osteoblasts and osteocytes and how this mechano-signaling pathway can regulate the bioavailability of sclerostin, a key protein regulating bone homeostasis.
Dr. Stains has published more than 65 peer reviewed articles, four book chapters, and has been consistently funded, including by the National Institutes of Health, Department of Defense, and the Maryland Stem Cell Research Fund. He is active in the American Society of Bone and Mineral Research, where he served as a member of the finance committee, and is on the editorial board for the society’s two journals, the Journal of Bone and Mineral Research and JBMR Plus. In 2020, he was named a Fellow of the American Society of Bone and Mineral Research. In addition, he is a standing member of the Skeletal Biology Development and Disease Study Section at the NIH, and has been a frequent ad hoc member of grant review study sections for the NIH, Arthritis Foundation, and VA.
To learn more about Dr. Stains, please see his faculty profile.
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