The Radiation Oncology-Biology Integration Network Oligometastasis (ROBIN OligoMET) Center is focused on understanding how radiation therapy can affect the metastatic process, particularly in low-volume or oligometastatic prostate cancer (PCa).
Our center brings together in-depth experience, knowledge, and high-level skills to study mechanisms of how radiation therapy (RT) can affect the metastatic process. This collaborative effort spans the following institutions:
- University of Maryland Baltimore (UMB)
- Weill Cornell Medicine (WCM)
- Thomas Jefferson University (TJU)
This multidisciplinary perspective enables us to bring the latest clinical trials, profiling and computational methods to bear on the most clinically relevant aspects of oligometastasis. The projects integrate state-of-the-art tissue, liquid and radiomic multi-parametric profiling techniques from humans complimented with syngeneic mouse tumor models in the context of a first-in-man phase II randomized trial. Data will be integrated using novel network methods to prioritize candidates for functional validation across projects.
Principal Researchers
This U54 ROBIN OligoMET Center is led by Drs. Phuoc Tran, contact Principal Investigator (PI), and Nicole Simone and Amit Sawant, both contact Multiple Principal Investigators (MPIs).
Contact PI
Phuoc T. Tran, MD, PhD
Professor of Radiation Oncology
Senior Vice Chair for Research
Department of Radiation Oncology
University of Maryland School of Medicine
Contact MPIs
Amit Sawant, PhD
Professor of Radiation Oncology
Vice Chair for Medical Physics
Department of Radiation Oncology
University of Maryland School of Medicine
Nicole Simone, MD, PhD
Margaret Q. Landenberger Professor
Vice Chair, Research & Diversity, Equality, & Inclusion
Sidney Kimmel Medical College at Thomas Jefferson University
Research Team
Project 1 (genomics, radiomics and liquid biopsies) is led by Drs. Tran, Ren and Sawant; Project 2 (metabolomics and disparities) is led by Dr. Simone; and the Resource Sharing and Cross-Training Cores are led by Drs. Luigi Marchionni, Sawant and Ren. To learn more about all of our researchers and projects, visit the Our Teams page.
Contact
For more information, please contact the Program Manager Jadyn Stewart or Senior Vice Chair for Research Dr. Phuoc Tran.
Collaborating Institutions
Follow the on ROBIN OligoMET Center: