Fuwen Zhou, BM, MM, Dr. rer. nat.

Dr. Zhou received his Bachelor Degree of Medicine (in Dental Medicine, BM) and Master Degree of Medicine (in Pharmacology, MM) from the Central South University Xiang-Ya School of Medicine in China. He then received his Dr. rer.nat. (in Cell Biology) from the University of Rostock, Germany. He was a post-doctoral fellow and research associate at the University of Tennessee.

Dr. Zhou combines state of the art of patch clamp electrophysiological, optogentical, chemogenetical, immunohistochemical, molecular biological, stereotaxic and behavioral analysis techniques, to investigate the neural function and behavior (HCN and TRP channel mediated excitability, chemical and electrical interconnection of local and centrifugal circuits, short-term plasticity and sensory and cognitive behaviors) in different brain regions (mainly olfactory bulb, cortex and basal ganglia) in healthy animals and animal models of human diseases (5xfamilial Alzheimer's disease, MPTP-Parkinson's disease and cortical dysplasia-epilepsy animal models).

HCN and TRP channels, neural excitation in healthy animals and animal models of human diseases (Alzheimer's disease, Parkinson's disease and epilepsy); olfactory bulb; cortex; local and centrifugal circuits; short-term plasticity; in vivo and in vitro neural electrophysiology; neuroanatomy with fiber photometry and multiphoton imaging

Puche AC, Hook C, Zhou FW^#. Cell type-specific and frequency-dependent centrifugal modulation in olfactory bulb output neurons in vivo. Journal of Neurophysiology 2024 131(6):1226-1239.

Zhou FW^#, Hook C, Puche AC^#. Frequency-dependent centrifugal modulation of the activity of different classes of mitral and tufted cells in olfactory bulb. Journal of Neurophysiology 2023, 129: 1515-1533.

Zhou FW^#, Puche AC^#. Short-term plasticity in cortical GABAergic synapses on olfactory bulb granule cells is modulated by endocannabinoids. Frontiers Cellular Neuroscience. 2021, 15: 629052.

Zhou FW^#, Shao ZY, Shipley MT, Puche AC^#. Short-term plasticity in glomerular inhibitory circuits shapes olfactory bulb output. Journal of Neurophysiology 2020, 123(3): 1120-1132.

Zhou FW, Puche AC, Shipley MT. Short-term plasticity at olfactory cortex to granule cell synapses requires Cav2.1 activation. Frontiers in Cellular Neuroscience 2018, 12: 387.

Zhou FW^#, Dong HW, Ennis M. Activation of β noradrenergic receptors enhances rhythmic bursting in mouse olfactory bulb external tufted cells. Journal of Neurophysiology 2016, 116(6): 2604-2614.

Zhou FW^#, Fortin JM, Chen HX, Martinez-Diaz H, Chang LJ, Reynolds BA, Roper SN. Functional integration of human neural precursor cells in mouse cortex. PLoS One 2015, 10(3): e0120281.

Zhou FW^#, Roper SN. Reduced synaptic and electrical connections of fast-spiking interneurons in experimental cortical dysplasia. Journal of Neurophysiology 2014, 112(6): 1277-1290.

Zhou FW^#, Roper SN. TRPC3 mediates hyperexcitability and epileptiform activity in immature cortex and experimental cortical dysplasia. Journal of Neurophysiology 2014, 111(6): 1227-1237.

Zhou FW^#, Roper SN. Impaired spatial recognition memory and synaptic plasticity in experimental cortical dysplasia. Epilepsia 2012, 53(5): 850-859.

Zhou FW, Roper SN. Altered firing rates and patterns in interneurons in experimental cortical dysplasia. Cerebral Cortex, 2011, 21(7): 1645-1658.

Zhou FW^#, Rani A., Martinez-Diaz H, Foster TC, Roper SN. Altered behavior in experimental cortical dysplasia. Epilepsia 2011, 52(12): 2293-2303.

Zhou FW, Roper SN. Densities of glutamatergic and GABAergic pre-synaptic terminals are altered in experimental cortical dysplasia. Epilepsia 2010, 51(8): 1468-1476.

Zhou FW, Jin Y, Matta SG, Xu M, Zhou FM. An ultra-short dopamine pathway regulates basal ganglia output. Journal of Neuroscience 2009, 29(33): 10424-10435.

Zhou FW, Chen HX, Roper SN. Balance of inhibitory and excitatory synaptic activity is altered in fast-spiking interneurons in experimental cortical dysplasia. Journal of Neurophysiology 2009, 102: 2514-2525.

Strauss U, Zhou FW (co-first author), Henning J, Battefeld A, Wree A, Köhling R, Haas SJP, Benecke R, Rolfs A, Gimsa U. Increase of extracellular potassium shapes the activity of subthalamic neurons similarly to a 6-hydroxydopamine lesion. Journal of Neurophysiology 2008, 99(6): 2902-2915.

Zhou FW, Matta SG, Zhou FM. Constitutively active TRPC3 channels regulate basal ganglia output neurons. Journal of Neuroscience 2008, 28(2): 473-482 (TWIJ article).

Zhou FW, Xu JJ, Zhao Y, Ledoux MS, Zhou FM. Opposite functions of histamine H₁ and H₂ receptors and H₃ receptor in substantia nigra pars reticulta. Journal of Neurophysiology 2006, 96(3): 1581-1591.

^#Corresponding author