Update Your ProfileAcademic Title:
Professor
Primary Appointment:
Medicine
Secondary Appointment(s):
Physiology
Administrative Title:
Interim Medical Director for the University of Maryland Lung Transplant Program
Additional Title:
Fellowship Program Director
Location:
Paca Pratt Building, 110 S Paca Street, 2nd floor
Phone (Primary):
(410) 328-8141
Fax:
(410) 328-0177
Education and Training
Davidson College, Davidson, North Carolina 1978-1982
University of Maryland School of Medicine 1982-1986
Internship, Residency and Chief Residency, Internal Medicine, Mercy Medical Center, Baltimore, MD 1986-1989
Fellowship, Division of Pulmonary & Critical Care Medicine, Duke University School of Medicine 1989-1992
Staff Physician, Pulmonary & Critical Care Medicine, Mercy Medical Center, Baltimore, Maryland 1992-2004
Assistant Professor, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 2005-2011
Fellowship Program Director, Pulmonary & Critical Care Medicine, University of Maryland School of Medicine, Baltimore, 2006-2014
Associate Professor, Department of Medicine, University of Maryland School of Medicine, Baltimore, 2011-present
Associate Professor, Department of Physiology, University of Maryland School of Medicine, Baltimore, 2013-present
Biosketch
Dr. Todd attends regularly on the inpatient and outpatient Pulmonary and Critical Care Medicine services at the University of Maryland Medical Center, the University of Maryland Mid-Town campus, and the Baltimore VA Medical Center. He is Director of the Clinical Care Network site at the University of Maryland as part of a national pulmonary fibrosis network through the Pulmonary Fibrosis Foundation. His educational responsibilities include the position as Co-Director of the Functional Systems course of University of Maryland School of Medicine.
Research/Clinical Keywords
Interstitial lung disease (ILD), pulmonary fibrosis, respiratory physiology
Highlighted Publications
Todd NW, Luzina IG, Atamas SP. Molecular and Cellular Mechanisms of Pulmonary Fibrosis. Fibrogenesis Tissue Repair 2012, 5:11.
Todd NW, Scheraga RG, Galvin JR, Iacono AT, Britt EJ, Luzina IG, Burke AP, Atamas SP. Lymphocyte Aggregates Persist and Accumulate in the Lungs of Patients with Idiopathic Pulmonary Fibrosis. J Inflamm Res 2013, 6: 63 - 70.
Luzina IG, Kopach P, Lockatell V, Kang PH, Nagarsekar A, Burke AP, Hasday JD, Todd NW, Atamas SP. Interleukin-33 Potentiates Bleomycin-induced Lung Injury. Am J Respir Cell Mol Biol 2013, 49:999-1008.
Kopach P, Lockatell V, Pickering EM, Haskell RE, Anderson RD, Hasday JD, Todd NW, Luzina IG, Atamas SP. IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism. J Biol Chem 2014, 289:11829-43.
Luzina IG, Lockatell V, Todd NW, Kopach P, Pentikis HS, Atamas SP. Pharmacological in vivo inhibition of S-nitrosoglutathione reductase attenuates bleomycin-induced inflammation and fibrosis. J Pharmacol Exp Ther 2015, 355:13-22.
Todd NW, Atamas SP, Luzina IG, Galvin JR. Permanent Alveolar Collapse is the Predominant Mechanism in Idiopathic Pulmonary Fibrosis. Expert Rev Respir Med 2015, 9:411-8.
Todd NW, Marciniak ET, Sachdeva A, Kligerman SJ, Galvin JR, Luzina IG, Atamas SP, Burke AP. Organizing Pneumonia/Non-specific Interstitial Pneumonia Overlap is associated with Unfavorable Lung Disease Progression. Respir Med.2015,109(11):1460-8.
Luzina IG, Lockatell V, Hyun SW, Kopach P, Kang PH, Noor Z, Liu A, Lillehoj EP, Lee C, Miranda-Ribera A, Todd NW, Goldblum SE, Atamas SP. Elevated Expression of NEU1 Sialidase in Idiopathic Pulmonary Fibrosis Provokes Pulmonary Collagen Deposition, Lymphocytosis, and Fibrosis. Am J Physiol Lung Cell Mol Physiol 2016, 310(10):L940-54.
Todd NW, Galvin JR, Sachdeva A, Luzina IG, Atamas SP, Burke AP. Microscopic Organizing Pneumonia and Cellular Nonspecific Interstitial Pneumonia are Widespread in Macroscopically Normal-Appearing Lung Tissue in Idiopathic Pulmonary Fibrosis. J Heart Lung Transplant 2016 [Epub ahead of print]
Research Interests
Dr. Todd's research interests are in the field of Interstitial Lung Disease (ILD) and Pulmonary Fibrosis. He works with Sergei Atamas, MD, PhD and Irina Luzina, MD, PhD from the Division of Rheumatology to advance understanding of these diseases. His research team uses animal models to understand basic mechanisms of disease, lung tissue from patients with ILD and pulmonary fibrosis to characterize molecular abnormalities, and clinical findings in patients (including histology and imaging) to characterize clinical outcomes and to correlate with basic science observations.
Awards and Affiliations
National Board of Medical Examiners (1987)
Internal Medicine, American Board of Internal Medicine (1989)
Pulmonary Disease, American Board of Internal Medicine (1992, 2002, 2013)
Critical Care Medicine, American Board of Internal Medicine (1993, 2003, 2013)