Erik R. Strauss, MD

2000-2004: B.S., Biology, University of Maryland Baltimore County, Baltimore, MD
2004-2008: M.D., University of Maryland School of Medicine, Baltimore, MD
2008-2009: Internship, Internal Medicine, Mercy Medical Center, Baltimore, MD
2009-2012: Residency, Department of Anesthesiology, UMMC, Baltimore, MD
2012-2013: Fellowship, Cardiothoracic Anesthesiology, UMMC, Baltimore, MD

2013-2022: Assistant Professor, Anesthesiology, UMSOM, Baltimore, MD

2022-2023: Associate Professor, Anesthesiology, UMSOM, Baltimore, MD

Blood Conservation Antifibrinolytic Therapy and Pharmacokinetics Cardiac Xenotransplantation Translational Research for Mitral Valve Repair

1. Mazzeffi M, Brown J, Bernstein W, Carter E, Lee IH, Strauss E. An Unusual Right Atrial Mass: A Misdiagnosis Identified by Intraoperative Transesophageal Echocardiography. J Cardiothorac Vasc Anesth. 2015;30(1):263-5. PMID: 26442454.
2. Tanaka KA, Mazzeffi MA, Strauss ER, Szlam F, Guzzetta NA. Computational simulation and comparison of prothrombin complex concentrate dosing schemes for warfarin reversal in cardiac surgery. J Anesth. 2015;30(3):369-76. PMID: 26749482.
3. Mazzeffi M, Lund L, Wallace K, Herrera AV, Tanaka K, Odonkor P, Strauss E, Rock P, Fiskum G. Effect of cardiopulmonary bypass on platelet mitochondrial respiration and correlation with aggregation and bleeding: a pilot study. Perfusion. 2016;31(6):508-15. PMID: 26916901.
4. Mazzeffi MA, Stafford P, Wallace K, Bernstein W, Deshpande S, Odonkor P, Grewal A, Strauss E, Stubbs L, Gammie J, Rock P. Intra-abdominal Hypertension and Postoperative Kidney Dysfunction in Cardiac Surgery Patients. J Cardiothorac Vasc Anesth. 2016;30(6):1571-1577. PMID: 27590464.
5. Strauss E, Taylor B, Mazzeffi M, Tanaka K, Odonkor P. The Auscultation of a Carbon Dioxide Embolization Event during Endoscopic Vein Harvest. Case Rep Anesthesiol. 2016;6947679. PMID: 27340571.
6. Odonkor P, Srinivas A, Strauss E, Williams B, Mazzeffi M, Tanaka KA. Perioperative Coagulation Management of a Hemophilia A Patient During Cardiac Surgery. Semin Cardiothorac Vasc Anesth. 2017; 21(4):312-320. PMID: 28388863.
7. Strauss ER, Mazzeffi MA, Williams B, Key NS, Tanaka KA. Perioperative management of rare coagulation factor deficiency states in cardiac surgery. Br J Anaesth. 2017;119(3):354-368. PMID: 28969316.
8. Mazzeffi M, Strauss E, Rabin J, Griffith B. Blunt Traumatic Injury to the Aortic Root and Aortic Valve. A A Pract. 2018;10(3):65-68. PMID: 29611823.
9. DiChiacchio L, Singh A, Lewis B, Ayares D, Strauss E, Odonkor P, Williams B, Deatrick K, Kon Z, Mohiuddin M. Insights into the Development of a Life-Sustaining Orthotopic Cardiac Xenotransplant Model. Transplantation. 2018;102(7):S315.
10. Deshpande SP, Mazzeffi MA, Strauss E, Hollis A, Tanaka KA. Prostacyclins in Cardiac Surgery: Coming of Age. Semin Cardiothorac Vasc Anesth. 2018;22(3):306-323. PMID: 29277148.
11. Abuelkasem E, Mazzeffi MA, Henderson RA, Wipfli C, Monroe A, Strauss ER, Chow JH, Tanaka KA. Clinical Impact of Protamine Titration-Based Heparin Neutralization in Patients Undergoing Coronary Bypass Grafting Surgery. J Cardiothorac Vasc Anesth. 2019;33(8):2153-2160. PMID: 30737123.
12. Judd M, Strauss E, Hasan S, Abuelkasem E, Li J, Deshpande S, Mazzeffi MA, Ogawa S, Tanaka KA. Clotting time results are not interchangeable between EXTEM and FIBTEM on rotational thromboelastometry. J Cardiothorac Vasc Anesth. 2019;34(6):1467-1473. PMID: 32139339.
13. Mazzeffi M, Strauss E, Meyer M, Hasan S, Judd M, Abuelkasem E, Chow J, Nandwani V, McCarthy P, Tanaka K. Coagulation Factor Levels and Underlying Thrombin Generation Patterns in Adult Extracorporeal Membrane Oxygenation Patients. Anesth Analg. 2019;129(3):659-666. PMID: 31425204.
14. Strauss E, Tanaka K, Mazzeffi M. HAS-BLED-A Canary in Cardiac Surgery Bleeding?  J Cardiothorac Vasc Anesth. 2019;33(6):1607-1609. PMID: 30928287.
15. Henderson RA, Mazzeffi MA, Strauss ER, Williams B, Wipfli C, Dawood M, Taylor BS, Tanaka KA. Impact of intraoperative high-volume autologous blood collection on allogeneic transfusion during and after cardiac surgery: a propensity score matched analysis. Transfusion. 2019;59(6):2023-2029. PMID: 30882929.
16. Pasrija C, Sawan MA, Sorensen E, Voorhees H, Shah A, Strauss E, Ton VK, DiChiacchio L, Kaczorowski DJ, Griffith BP, Pham SM, Kon ZN. Less invasive left ventricular assist device implantation may reduce right ventricular failure. Interact Cardiovasc Thorac Surg. 2019;29(4):592-598. PMID: 31326991.
17. Morita Y, Strauss E, Tanaka KA. Low ACT After High-Dose Heparin: Is Hemodilution Best Option to Pass by Syclla and Charybdis?  A A Pract. 2019;13(12):479. PMID: 31633487.
18. Goerlich C, Singh A, Kaczorowski D, Abdullah M, Lewis B, Tatarov I, Hershfeld A, Zhang T, Strauss E, Odonkor P, Williams B, Ayares D, Griffith B, Mohiuddin M. The Use of Minimally Ischemic Cardiac Preservation Techniques to Overcome Perioperative Cardiac Xenograft Dysfunction (PCDX) in Life-Supporting Cardiac Xenotransplantation Model. Transplantation. 2020;104(S3):S636.
19. DiChiacchio L, Singh AK, Lewis B, Zhang T, Hardy N, Pasrija C, Morales D, Odonkor P, Strauss E, Williams B, Deatrick KB, Kaczorowski DJ, Ayares D, Griffith BP, Bartlett ST, Mohiuddin MM. Early experience with preclinical peri-operative cardiac xenograft dysfunction in a single program. Ann Thorac Surg. 2020;109(5):1357-1361. PMID: 31589847.
20. Tanaka KA, Henderson RA, Strauss ER. Evolution of viscoelastic coagulation testing in the perioperative setting. Expert Rev Hematol. 2020;13(7):697-707. PMID: 32310702.
21. Goerlich CE, Kaczorowski D, Singh A, Abdullah M, Lewis B, Zhang T, Tatarov I, Sentz F, Hershfeld A, Odonkor P, Williams B, Strauss E, Ayares D, Griffith B, Mohiuddin M. Human Thrombomodulin Transgene Expression Prevents Intracardiac Thrombus in Life Supporting Pig-to-Baboon Cardiac Xenotransplantation. J Heart Lung Transplant. 2020;39(4):S145.
22. Goerlich C, Singh A, Kaczorowski D , Abdullah M, Lewis B, Tatarov I, Hershfeld A, Zhang T, Strauss E, Odonkor P, Williams B, Ayares D, Griffith B, Mohiuddin M. Lack of Human Thrombomodulin Gene Expression in Life Supporting Pig-to-Baboon Cardiac Xenotransplantation Models Accelerate Antibody Mediated Rejection. Transplantation. 2020;104(S3):S635.
23. Tanaka KA, Mondal S, Morita Y, Williams B, Strauss ER, Cicardi M. Perioperative Management of Patients With Hereditary Angioedema With Special Considerations for Cardiopulmonary Bypass. Anesth Analg. 2020;131(1):155-169. PMID: 32102012.
24. Strauss ER, Li S, Henderson R, Carpenter R, Guo D, Thangaraju K, Katneni U, Buehler PW, Gobburu JV, Tanaka KA. A Pharmacokinetic and Plasmin-Generation Pharmacodynamic Assessment of a Tranexamic Acid Regimen Designed for Cardiac Surgery With Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. 2021;36(8 Pt A):2473-2482. PMID: 35094925.
25. Chow JH, Strauss E, Mazzeffi MA. Angiotensin II and Vasoplegia in Cardiac Surgery: Paradigm Changer or Costly Contender?  J Cardiothorac Vasc Anesth. 2021;35(1):59-60. PMID: 32950345.
26. Goerlich CE, Griffith B, Singh AK, Abdullah M, Singireddy S, Kolesnik I, Lewis B, Sentz F, Tatarov I, Hershfeld A, Zhang T, Strauss E, Odonkor P, Williams B, Tabatabai A, Bhutta A, Ayares D, Kaczorowski DJ, Mohiuddin MM. Blood Cardioplegia Induction, Perfusion Storage and Graft Dysfunction in Cardiac Xenotransplantation. Front Immunol. 2021;12:667093. PMID: 34177906.
27. Henderson RA, Judd M, Strauss ER, Gammie JS, Mazzeffi MA, Taylor BS, Tanaka KA. Hematologic evaluation of intraoperative autologous blood collection and allogeneic transfusion in cardiac surgery. Transfusion. 2021;61(3):788-798. PMID: 33423288.
28. Gammie JS, Quinn RW, Strauss ER, Wang L, D'Ambra MN, Hung J, Bernstein DA, Tran D, Rice MK, Holmes SD, Pasrija C. Initial Clinical Experience with Mitral Valve Translocation for Secondary Mitral Regurgitation. Ann Thorac Surg. 2021;S0003-4975(21):00051-5. PMID: 33440174.
29. Pasrija C, Quinn R, Bernstein D, Tran D, Alkhatid H, Rice M, Morales D, Shah A, Ghoreishi M, Strauss E, Henderson R, D'Ambra M, Gammie J. Mitral valve translocation: A novel operation for the treatment of secondary mitral regurgitation. The Annals of Thoracic Surgery. 2021;112(6):1954-1961. PMID: 34419436.
30. Strauss E, Dahmane E, Judd M, Guo D, Williams B, Meyer M, Gammie JS, Taylor B, Mazzeffi MA, Gobburu JV, Tanaka KA. A Pharmacokinetic and Pharmacodynamic Investigation of an ε-Aminocaproic acid regimen designed for the context of cardiac surgery with cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 2022;35(2):406-417. PMID: 32811752.
31. Shah A, Goerlich CE, Pasrija C, Hirsch J, Fisher S, Odonkor P, Strauss E, Ayares D, Mohiuddin MM, Griffith BP. Anatomical Differences Between Human and Pig Hearts and Their Relevance for Cardiac Xenotransplantation Surgical Technique. JACC Case Rep. 2022;4(16):1049-1052. PMID: 36062051.
32. Strauss ER, Taneja M, Booth R, Sankova S, Anders G. Antifibrinolytics in Cardiac Surgery: What Is the Best Practice in 2022?  Curr Anesthesiol Rep. 2022;12(4):501-507.
33. Odonkor P, Strauss E, Williams B. Ethical considerations during a pioneering surgical procedure: porcine cardiac xenotransplantation. Br J Hosp Med (Lond). 2022;83(6):1-7. PMID: 35787171.
34. Tanaka KA, Henderson R, Thangaraju K, Morita Y, Mazzeffi MA, Strauss E, Katneni U, Buehler PW. In vitro effects of emicizumab on activated clotting time in blood samples from cardiac surgical patients. Haemophilia. 2022;28(1):183-190. PMID: 34735039.
35. Strauss ER, Quinn RW, Pasrija C, Henderson R, Holmes SD, D'Ambra MN, Gammie JS. Intraoperative echocardiographic assessment of mitral valve translocation. Eur J Cardiothorac Surg. 2022;62(2):ezac133. PMID: 35277715.
36. Strauss ER, Odonkor PN, Williams B. Porcine Orthotopic Cardiac Xenotransplantation: The Role and Perspective of Anesthesiologists. J Cardiothorac Vasc Anesth. 2022;36(8 Pt B):2847-2850. PMID: 35537973.
37. Mohiuddin MM, Goerlich CE, Singh AK, Zhang T, Tatarov I, Lewis B, Sentz F, Hershfeld A, Braileanu G, Odonkor P, Strauss E, Williams B, Burke A, Hittman J, Bhutta A, Tabatabai A, Gupta A, Vaught T, Sorrells L, Kuravi K, Dandro A, Eyestone W, Kaczorowski DJ, Ayares D, Griffith BP. Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months. Xenotransplantation. 2022;29(3):e12744. PMID: 35357044.
38. Mazzeffi MA, Henderson R, Powell E, Strauss E, Williams B, Tanaka K, Yang S, Deatrick K, Madathil R. Thrombopoietin, Soluble CD40 Ligand, and Platelet Count During Veno-arterial Extracorporeal Membrane Oxygenation. ASAIO J. 2022;68(5):e77-e79. PMID: 34081052.
39. Strauss ER, VanDyck K, Mazzeffi MA. Tranexamic acid for cesarean delivery: induction of a regimen for postpartum hemorrhage?  Am J Obstet Gynecol. 2022;S0002-9378((22):00672-X. PMID: 35998746.
40. Pasrija C, Quinn R, Strauss E, Wang L, Tran D, D'Ambra MN, Gammie JS. Translocation of the Mitral Valve in an Acute Large Animal Model. J Cardiovasc Transl Res. 2022;15(5):1100-1107. PMID: 35175554.
41. Ghoreishi M, Chahal D, Shah A, Kang J, Hirsch J, Tran D, McCloskey D, Shkullaku M, Gupta A, Strauss ER, Dahi S, Taylor BS, Toursavadkohi S. First-in-Human Endovascular Aortic Root Repair (Endo-Bentall) for Acute Type A Dissection. Circ Cardiovasc Interv. 2023;16(10):e013348. PMID: 37737022.
42. Strauss ER, Odonkor PN, Williams B, Choi S, Mueller J, Taylor B, Shah A, Goerlich CE, Mohiuddin MM, Griffith BP. Intraoperative Management of an Orthotopic Porcine-to-Human Cardiac Xenotransplant. Ann Thorac Surg. 2023;115(3):784-786.PMID: 36621667.