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Vinay Shukla, PhD

Academic Title:

Post Doc Fellow

Primary Appointment:

Obstetrics, Gynecology and Reproductive Sciences

Education and Training

DDU Gorakhpur University, India, B.Sc., Zoology & Chemistry, 2010

DDU Gorakhpur University, India, M.Sc., Biotechnology, 2012

CSIR-Central Drug Research Institute (AcSIR), India, Ph.D., Reproductive Biology, 2019

University of Kansas Medical Center, US, Postdoctoral Fellow, Reproductive Biology, 2024

Biosketch

Dr. Vinay Shukla is a Postdoctoral Fellow in the Department of Obstetrics, Gynecology, and Reproductive Sciences at the University of Maryland School of Medicine, Baltimore, USA. Dr. Shukla earned his undergraduate and master’s degrees from DDU Gorakhpur University, India. He completed his Ph.D. at the CSIR-Central Drug Research Institute, India. Dr. Shukla has over 12 years of experience in Reproductive Biology. He is a member of several scientific organizations, including SRI, SSR, ISSRF, SRBCE, IISc, APA and DOHaD. Dr. Shukla has received numerous honors, including the Young Scientist Award from ISSRF, the BRTP Postdoctoral Award, NIH K-INBRE Postdoctoral Award, and the Top Reviewing Editor Award from the Society for the Study of Reproduction, US.

Research/Clinical Keywords

Maternal inflammation, placental development, embryo implantation and decidualization.

Highlighted Publications

Vinay Shukla*, Ayelen Moreno-Irusta, Kaela M. Varberg, Marija Kuna, Anna M. Galligos, Khursheed Iqbal, John D. Aplin, Rahul H. Choudhury, Hiroaki Okae, Takahiro Arima, Michael J. Soares*. NOTUM mediated WNT signaling drives extravillous trophoblast cell lineage development. (2024) Proceedings of the National Academy of Sciences, 121 (40) e2403003121. (*co-corresponding author).

Vinay Shukla*, Khursheed Iqbal, Hiroaki Okae, Takahiro Arima, Michael J. Soares*. Effects of aryl hydrocarbon receptor ligand TCDD on human trophoblast cell development. (2024) BioRxiv,  https://doi.org/10.1101/2024.08.27.609205 (*co-corresponding author).

Vinay Shukla*, Michael J Soares*. Modeling trophoblast cell-guided uterine spiral artery transformation in the rat. (2022) International Journal of Molecular Sciences, 23(6):2947. (*co-corresponding author).

Vinay Shukla, Jyoti B Kaushal, Rohit Kumar, Pooja Popli, Promod K Agnihotri, Kalyan Mira, Anila Dwivedi. Microtubule depolymerization attenuates WNT4/CaMKIIα signaling in mouse uterus and leads to implantation failure. (2019) Reproduction 158 (1), 47-59.

Vinay Shukla, Jyoti B Kaushal, Pushplata Sankhwar, Murli Manohar, Anila Dwivedi. Inhibition of TPPP3 attenuates β-catenin/NF-κB/COX-2 signaling in endometrial stromal cells and impairs decidualization. (2019) Journal of Endocrinology 240, 1-14.

Vinay Shukla, Pooja Popli, Jyoti B Kaushal, Kanchan Gupta, Anila Dwivedi. Uterine TPPP3 plays important role in embryo implantation via modulation of β-catenin. (2018) Biology of Reproduction 99, 982–999.

Vinay Shukla, Vishal Chandra, P. Sankhwar, Pooja Popli, Jyoti B Kaushal, Vijay K Sirohi, Anila Dwivedi. Phytoestrogen genistein inhibits EGFR/PI3K/NF-kB activation and induces apoptosis in human endometrial hyperplasial cells. (2015) Royal Society of
Chemistry Advances 5, 56075-56085.

Awards and Affiliations

2016 Senior Research Fellowship from Indian Council of Medical Research, New Delhi, India

2018 Best Poster Award from Animal Physiologists Association

2019 CSIR- Central Drug Research Institute Incentive Award for Publication

2019 Prof. S. S. Guraya Young Scientist Award from Indian Society for the Study of Reproduction and Fertility, India

2020 KU Medical Center - Biomedical Research Training Program (BRTP) Postdoctoral Award

2020 Kansas IDeA Network of Biomedical Research Excellence (K-INBRE) Postdoctoral Award, KS, US

2023 2022 Biology of Reproduction Top Reviewing Editor Award, by Society for the Study of Reproduction: Biology of Reproduction (Journal), Ottawa, Canada

Grants and Contracts

2016-2019  PI: Vinay Shukla

“Role of tubulin polymerization promoting protein 3 (TPPP3) in the embryo

implantation and decidualization"

Senior Research Fellowship, Indian Council of Medical Research, New Delhi,

India

Total Costs: INR 1,128,000

 

2020-2020  PI: Vinay Shukla

“Role of WNT Signaling in Trophoblast Cell Differentiation and Placental Disease”

KUMC Biomedical Research Training Program Postdoctoral Award

Total Costs: $13,000

 

2020-2021  PI: Vinay Shukla

“Role of WNT Signaling in Trophoblast Cell Differentiation and Placental Disease”

NIH Kansas IDeA Network of Biomedical Research Excellence (K-INBRE)

Postdoctoral Award

Total Costs: $38,248

Professional Activity

2019-Present Ad Hoc Reviewer, Biology of Reproduction, Biomedicines, Cells, Environmental Health Perspectives, European, Journal of Obstetrics & Gynecology and Reproductive Biology, Frontiers in Cell and Developmental Biology, Frontiers in Endocrinology, Frontiers in Genetics, Frontiers in Medical Technology, Frontiers in Physiology, Frontiers in Psychology, Frontiers in Reproductive Health, Gene, Gene Reports, Organoids, International Journal of Environmental Research and Public Health, International Journal of Molecular Sciences, Journal of Clinical Medicine, Journal of Reproductive Immunology, Life Science Alliance, Medicina, Placenta, PLOS ONE, Reproductive Biology, Reproductive BioMedicine Online, Reproductive Medicine, Scientific Report- Nature, Stem Cell Reports- Cell, Toxics.

2021-Present Review Editor, Frontiers in Physiology (Section: Developmental Physiology)

2021-Present Review Editor, Frontiers in Reproductive Health (Section: Gynecology)

2021-Present Review Editor, Frontiers in Medical Technology (Section: Regenerative Technologies)

2021 Poster Session Judge in the 19th Annual Kansas-IDeA Network of Biomedical Research Excellence Symposium, Kansas City, KS, USA

2022-Present Review Editor, Frontiers in Endocrinology (Section: Reproduction)

2022-Present Review Editor, Frontiers in Global Women's Health (Section: Maternal Health)

2022 Poster and Oral talk Abstract Reviewer, 69th Annual Meeting of Society for Reproductive Investigation, Denver, CO, USA

2022 Poster Session Judge, 69th Annual Meeting of Society for Reproductive Investigation, Denver, CO, USA

2024 Poster and Oral talk Abstract Reviewer, 57th Annual Meeting of Society for the Study of Reproduction, Dublin, Ireland