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Timothy R. Miller, MD

Academic Title:

Professor

Primary Appointment:

Diagnostic Radiology and Nuclear Medicine

Secondary Appointment(s):

Neurosurgery

Additional Title:

Director of Neurointerventional Surgery Fellowship

Location:

22 S Greene Street Baltimore, MD 21201

Phone (Primary):

410-328-5112

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Education and Training

Education

  • 2000 | B.A., Chemistry, Case Western Reserve University (Summa Cum Laude)           
  • 2005 | M.D., Perelman School of Medicine, University of Pennsylvania

Post-Graduate

  • 2006 | Internship, Penn Presbyterian Medical Center
  • 2007 | Residency, Diagnostic Radiology, Harbor-UCLA Medical Center
  • 2010 | Residency, Diagnostic Radiology, 
  • 2011 | Fellowship, Diagnostic Neuroradiology, Hospital of the University of Pennsylvania
  • 2012 | Fellowship, Interventional Neuroradiology, Hospital of the University of Pennsylvania

Certifications

  • 2010 | Diplomat, American Board of Diagnostic Radiology
  • 2016 | Neuroradiology Certificate of Added Qualifications

Biosketch

Dr. Miller is a board-certified radiologist with subspecialty certification in diagnostic neuroradiology and neurointerventional surgery. He graduated Summa cum Laude from Case Western Reserve University in 2000, and then from the Perelman School of Medicine at the University of Pennsylvania in 2005. Dr. Miller subsequently completed his radiology residency at University Hospitals Case Medical Center in Cleveland, Ohio, followed by advanced fellowship training in diagnostic and interventional neuroradiology at the Hospital of the University of Pennsylvania.

Dr. Miller has been an active member of the neurointerventional surgery section at the University of Maryland since 2012. There, Dr. Miller’s clinical duties have primarily consisted of the diagnosis and treatment of vascular abnormalities of the central nervous system, including cerebral aneurysms and acute large-vessel ischemic strokes. He also has expertise in minimally invasive percutaneous interventions of the neck and spine. Dr. Miller has taken an active role in educating residents and fellows and is currently the program director of the Neuroendovascular Intervention Fellowship. He is committed to educating the next generation of physicians and fellows in neurointerventional techniques.

Dr. Miller is involved in cutting edge clinical research and has published work in prestigious journals including Radiology, American Journal of Neuroradiology, and Journal of Neurointerventional Surgery. In addition, he has contributed to several book chapters. At this time, Dr. Miller is actively pursuing research aimed at better understanding flow diversion treatment of intracranial aneurysms as well as the role of mechanical thrombectomy for the treatment of acute, large-vessel ischemic stroke. He is the site principal investigator at the University of Maryland for several on-going clinical trials and registries, including the REal-World Analyses of Stroke – Thrombus Occlusion Retrieval Registry and the Trevo® Retriever Registry Post Market Surveillance Study.

Dr. Miller is a member of the Society of Neurointerventional Surgery, American Society of Neuroradiology, and the Radiological Society of North America. Dr. Miller has also served on the Educational Exhibit committee of the annual meeting of the Radiologic Society of North America. Finally, he is a reviewer for the American Journal of Neuroradiology, Journal of Neurointerventional Surgery, and the British Medical Journal.

Research/Clinical Keywords

Pipeline embolization device, mechanical thrombectomy acute ischemic stroke, neuro-interventional radiology

Highlighted Publications

  1. Miller TR, Jindal G, Krejza J, Gandhi D. Impact of Endovascular Technique on FluoroscopyUsage: Stent-Assisted Coiling Versus Flow Diversion of Paraclinoid Internal Carotid Artery Aneurysms. Neuroradiology Journal. Accepted for publication August 2014.

  2. Jindal G, Miller T, Beaty N, Puri A, Gandhi D. Ultra-small diameter coils for treatment of intracranial aneurysms. Interventional neuroradiology: journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2015;21:50-54.

  3. Miller TR, Shivashankar R, Mossa-Basha M, Gandhi D. Reversible cerebral vasoconstriction syndrome, part 1: Epidemiology, pathogenesis, and clinical course. AJNR. American journal of neuroradiology, 2015.

  4. Miller TR, Shivashankar R, Mossa-Basha M, Gandhi D. Reversible cerebral vasoconstriction syndrome, part 2: Diagnostic work-up, imaging evaluation, and differential diagnosis. AJNR. American journal of neuroradiology, 2015.

  5. Miller TR, Gandhi D. Intracranial Dural Arteriovenous Fistulae: Clinical Presentation and Management Strategies. Stroke; a journal of cerebral circulation. Jul 2015;46(7):2017-2025.

  6. Le EJ, Miller T, Serulle Y, et al. Use of Pipeline Flex is associated with reduced fluoroscopy time, procedure time, and technical failure compared with the first-generation Pipeline embolization device. Journal of neurointerventional surgery, March 2016.

  7. Jindal G, Miller TR, Serulle Y, Gandhi D. Stent retrieval thrombectomy in acute stoke is facilitated by the concurrent use of intracranial aspiration catheters. Journal of neurointerventional surgery, August 2016.

Clinical Specialty Details

Board certified diagnostic and interventional radiologist. Additional board certification in the sub-specialty of neuroradiology. Clinical and research focus are in the areas of cerebrovascular disorders, including cerebral aneurysms, vascular malformations, and acute large vessel ischemic stroke. 

Awards and Affiliations

Awards

  • 2000 | Admission to Phi Beta Kappa Honor Society, Case Western Reserve University
  • 2000 | Graduated Summa Cum Laude, Case Western Reserve University
  • 2021 | Bruce Roberts Line Prize in Diagnostic Radiology, UMSOM

Professional Society Memberships

  • Radiological Society of North America (RSNA)
  • American College of Radiology
  • Senior Member, American Society of Neuroradiology (ASNR)
  • Senior Member, Society of Neurointerventional Surgery (SNIS)
  • Eastern Neuroradiological Society (ENRS)
  • Association of Program Directors in Radiology (APDR)

Grants and Contracts

ACTIVE GRANTS

09/01/14-present | Co-Inv, Site-PI: Dheeraj Gandhi (1%)

  • “BARREL: Prospective, Multi-Center, Single-Arm Study of the Reverse Medical Barrel™ Vascular Reconstruction Device (VRD) for Adjunctive Treatment to Embolic Coils for Wide-Neck, Intracranial, Bifurcating/ Branching Aneurysms of Middle Cerebral and Basilar Arteries”
  • Multi-center trial
  • Sponsor: MedtronicAward amount: $26,232
  • Assist in patient recruitment, data collection

09/15/15-present | Co-Inv, Site-PI: Gaurav Jindal (1%)

  • “A Prospective, Multi-center, Single Arm Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System when Used in Conjunction with Endovascular Coil Embolization in the Treatment of Wide-necked Saccular Intracranial Aneurysms”
  • Multi-center trial
  • Sponsor: Cerenovus, DePuy Synthes Products, Inc.
  • Award amount: $99,995
  • Assist in patient recruitment, data collection

01/30/18-present | Co-Inv, Site-PI: Howard Eisenberg (1%)

  • “A Pivotal Clinical Trial of the Management of the Medically-Refractory Dyskinesia Symptoms or Motor Fluctuation of Advanced Idiopathic Parkinson’s Disease With Unilateral Lesioning of the Globus Pallidum Using the ExAblate Neuro System”
  • Multi-center trial
  • Sponsor: InSightec
  • Award amount: $830,971
  • Assist in treatment planning and execution

02/21/18-present | Co-Inv, Site PI: Gaurav Jindal (1%)

  • “Ruptured Aneurysms Treated with Hydrogel Coils – RAGE”
  • Multi-center trial
  • Sponsor: Microvention
  • Award amount: $126,350
  • Assist in patient recruitment, data collection

07/11/18-present | Co-Inv, Site-PI: Graeme Woodworth (1%)

  • “A Study to Evaluate the Safety and Feasibility of Exablate Model 4000 Type-2 to Temporarily Mediate Blood-Brain Barrier Disruption (BBBD) in Patients with Suspected Glioblastoma in the Setting of Planned Surgical Interventions”
  • Single center trial
  • Sponsor: InSightec
  • Award amount: $239,027
  • Assist in treatment planning and execution

08/16/18-present | Co-Inv, Site-PI: Dheeraj Gandhi (1%)

  • “PHIL DAVF: Study of PHIL Embolic System in the Treatment of Intracranial Dural Arteriovenous Fistulas”
  • Multi-center trial
  • Sponsor: MicroVention
  • Award amount: $130,000
  • Assist in patient recruitment, data collection

04/25/19-present | Co-Inv, Site-PI: Dheeraj Gandhi (1%)

  • “Phase 1 Clinical Trial for MR Guided Focused Ultrasound (FUS) thalamotomy of Central lateral thalamic nucleus for the treatment of Neuropathic Pain”
  • Single center trial
  • Sponsor: InSightec
  • Award amount: $312,626
  • Assist in data gathering, data analysis

05/30/20-present | Site-PI (3%)

  • “Sofia Aspiration System as First Line Technique”
  • Multi-center registry
  • Sponsor: MicroVention
  • Award amount: $90,270
  • Assist in data gathering, data analysis

01/25/21-present | Co-Inv, Site-PI: Dheeraj Gandhi (1%)

  • “MR Guided Focused Ultrasound (FUS) for the treatment of Trigeminal Neuralgia”
  • Single center trial
  • Sponsor: InSightec
  • Award amount: $347,880
  • Assist in patient recruitment, data gathering, data analysis

05/28/21-present | Site-PI (3%)

  • “A Prospective, Open-Label, Multi-Center, Single-Arm Trial Designed to Assess the Safety, Performance and Efficiency of the NeVa Stent Retriever in the Treatment of Large Vessel Occlusion Strokes”
  • Multi-center trial
  • Sponsor: Vesalio
  • Award amount: $86,241
  • Assist in patient recruitment, data gathering, data analysis

 

PENDING GRANTS

Site-PI (3%)

  • “Post-Market Surveillance Study to Evaluate the Long-Term Safety and Effectiveness of the Web Device”
  • Multi-center trial
  • Sponsor: Microvention
  • Award amount: Pending
  • Assist in patient recruitment, data gathering, data analysis

 

COMPLETED GRANTS

11/02/11-06/02/17 | Co-Inv (1%), Site-PI: Gaurav Jindal      

  • “Hydrogel Endovascular Aneurysm Treatment Trial (HEAT)”   
  • Multi-center trial
  • Sponsor: Stryker
  • Award amount: $34,889
  • Assist in patient recruitment, data collection

08/01/13-03/31/21 | Co-Inv (1%), PI: Gaurav Jindal

  • “ULTRA: Ultra Coils from Start to Finish for the Endovascular Repair of Small Intracranial Aneurysms”   
  • Multi-center trial
  • Sponsor: Stryker
  • Award amount: $744,774
  • Assist in patient recruitment, data collection

11/16/13-11/25/14 | Co-Inv (1%), Site PI: Elias Melhem

  • “Gadobutrol Enhanced MRA of the Supra-aortic Vessels
  • Multi-center trial
  • Sponsor: Bayer
  • Award amount: $79,295
  • Assist in patient recruitment, data collection

11/25/13-12/11/17 | Site-PI (5%)

  • “Trevo Retriever Registry: Post Market Surveillance Study”
  • Multi-center trial
  • Sponsor: Stryker
  • Award amount: $337,430
  • Assist in patient recruitment, data gathering, data analysis

11/10/14-08/20/15 | Co-Inv (1%), Site-PI: Dheeraj Gandhi

  • “A Pivotal Study of MicroVention, Inc. Neurovascular Self-expanding Retrievable Stent System LVIS”
  • Multi-center trial
  • Sponsor: MicroVention
  • Award amount: $45,350
  • Assist in patient recruitment, data collection

12/08/15-04/03/17 | Co-Inv (1%), Site-PI: Gaurav Jindal       

  • “Systemic Evaluation of Patients Treated with Neurothrombectomy Devices for Acute Ischemic Stroke (STRATIS) Registry”     
  • Multi-center acute stroke registry
  • Sponsor: Medtronic
  • Award amount: $96,000
  • Assist in patient recruitment, data collection

12/20/15-07/21/16 | PI (3%)

  • “Pipeline Flex versus Classic Retrospective Study”
  • Single-center retrospective trial
  • Sponsor: Medtronic
  • Award amount: $20,000
  • Assist in study design, data gathering, data analysis

01/13/16-06/01/19 | Site-PI (3%)

  • “Apollo Onyx Delivery Micro Catheter Post Market Safety Study”       
  • Multi-center trial
  • Sponsor: Medtronic
  • Award amount: $32,500
  • Assist in patient recruitment, data gathering, data analysis
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