Update Your ProfileAcademic Title:
Associate Professor
Primary Appointment:
Medicine
Email:
Location:
22 S. Greene Street
Phone (Primary):
410-328-6842
Fax:
410-328-6896
Education and Training
MD - Hacettepe University SOM, Ankara, Turkey
Residency, Internal Medicine- Hacettepe University SOM, Ankara, Turkey
Fellowship, Hematology- Hacettepe University SOM, Ankara, Turkey
Internship, Internal Medicine- University of Arkansas for Medical Sciences, Little Rock, AR
Residency, Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR
Fellowship, Hematology Oncology -Yale University School of Medicine, New Haven, CT
Biosketch
I find immunology and biology of the plasma cells fascinating and accordingly, my passion in the field of hematology- oncology lies in plasma cell dyscrasias such as multiple myeloma, primary (AL) amyloidosis, Waldenstrom macroglobulinemia, POEMS syndrome and other types of disorders that are all related to plasma cell dyscrasias.
Research/Clinical Keywords
Diagnosis and treatment of plasma cell dyscrasias which include diseases such as multiple myeloma, AL amyloidosis, Waldenstrom's macroglobulinemia, POEMS syndrome
Highlighted Publications
Das R, Strowig T, Verma R, Koduru S, Hafemann A, Hopf S, Kocoglu MH, Borsotti C, Zhang L, Branagan A, Evnon E, Manz MG, Flavell RA, Dhodapkar MV. Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice. Nat Med 2016 Oct 10. Nov;22(11):1351-1357
Kocoglu M, Hutchins S, Hammond E, Gokden N, Hough A, Smith E, Anaissie E, Barlogie B. An unusual clinical course of cardiac Ig deposition disease. Bone Marrow Transplant, 2009 Sep;44(5):321-2
Sayinalp N, Haznedaroglu IC, Buyukasik Y, Goker H, Aksu S, Kocoglu H, Ozcebe OI, Kosar A, Kirazli S, Dundar SV. Protein C inhibitor and serum amyloid A in immune thrombocytopaenic purpura. J Int Med Res. 2004 Jan-Feb;32(1):62-5.
Additional Publication Citations
Ozatli D, Buyukasik Y, Haznedaroglu IC, Kocoglu H ( published as Koc H– error),Kosar A, Simsek H. Could serum haptoglobin concentration be used as a marker of hypersplenism in chronic liver disease ? AmJ Gastroenterol.1998 Dec;93(12):2641-2
Ozatli D, Kocoglu H, Haznedaroglu IC, Kosar A, Buyukasik Y, Ozcebe O, Kirazli S, Dundar SV. Circulating thrombomodulin, thrombospondin, and fibronectin in acute myeloblastic leukemias. Haematologia (Budap). 1999;29(4):277-83
Kocoglu H, Haznedaroglu I.C., Kocoglu G, Karakus S, Goker H, Ertugrul D, Buyukasik Y, Sayinalp N, Ozcebe O.I., Dundar S, Kirazli S. Hemostasis and oncostatin-m levels in reactive versus clonal thrombocytosis. Exp.Hematol.2001 Volume 29, Page 97 (Dissertation thesis in Hematology)
Asik M.,Haznedaroglu IC ,Karakus S ,Aksu S. ,Kocoglu H., Buyukasik Y.,Goker H., Ertugrul D., Sayinalp N., Ozcebe O., Kirazli S., Dundar S. Bone marrow and peripheral blood C-kit ligand concentrations in patients with thrombocytosis and thrombocytopenia. Exp. Hematol. 2002 June, Volume 30, Pages 102
Ozcebe OI, Karakus S, Haznedaroglu IC, Goker H, Kosar A, Kocoglu H, Buyukasik Y, Sayinalp N, Kirazli S.Plasma thrombospondin in immune thrombocytopenic purpura. J Int Med Res. 2002 Jan- Feb;30(1):52-5.
Sayinalp N, Haznedaroglu IC, Buyukasik Y, Goker H, Aksu S, Kocoglu H, Ozcebe OI, Kosar A, Kirazli S, Dundar SV. Protein C inhibitor and serum amyloid A in immune thrombocytopaenic purpura. J Int Med Res. 2004 Jan-Feb;32(1):62-5.
Miceli MH, Grazziutti ML, Woods G, Zhao W, Kocoglu MH, Barlogie B, Anaissie E. Strong Correlation between serum Aspergillus Galactomannan and Aspergillosis outcome in patients with hematological cancer: clinical and research implications. Clin Infect Dis. 2008 May 1;46(9):1412-22
Motwani P, Kocoglu M, Lorsbach RB.Systemic mastocytosis in association with plasma cell dyscrasias: report of a case and review of the literature. Leuk Res 2009 Jun;33(6):856-9
Kocoglu M, Hutchins S, Hammond E, Gokden N, Hough A, Smith E, Anaissie E, Barlogie B. An unusual clinical course of cardiac Ig deposition disease. Bone Marrow Transplant, 2009 Sep;44(5):321-2
Kartik Sehgal, Rituparna Das, Lin Zhang, Rakesh Verma, Yanhong Deng, Mehmet Kocoglu, Juan Vasquez, Srinivas Koduru, Yan Ren, Maria Wang, Suzana Cuoto, Mike Breider, Donna Hansel, Stuart Seropian, Dennis Cooper, Anjan Thakurta, Xiaopan Yao, Kavita M. Dhodapkar, and Madhav V. Dhodapkar. Clinical and pharmacodynamic analysis of pomalidomide dosing strategies in myeloma: impact of immune activation and cereblon targets. Blood 2015 Apr 13. pii: blood-2014-11-611426
Das R, Strowig T, Verma R, Koduru S, Hafemann A, Hopf S, Kocoglu MH, Borsotti C, Zhang L, Branagan A, Evnon E, Manz MG, Flavell RA, Dhodapkar MV. Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice. Nat Med 2016 Oct 10. Nov;22(11):1351-1357
Badros A, Hyjek E, Ma N, Lesokhin A, Dogan A, Rapoport AP, Kocoglu M, Lederer E, Philip S, Milliron T, Dell C, Goloubeva O, Singh Z. Pembrolizumab, pomalidomide and low dose dexamethasone for relapsed / refractory multiple myeloma. Blood 2017 May 1pii: blood-2017-03-775122. doi: 10.1182/blood-2017-03-775122.
Links of Interest
http://www.umm.edu/programs/cancer/