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Rebecca J. Henry, PhD

Academic Title:

Research Associate

Primary Appointment:

Anesthesiology

Phone (Primary):

(410) 328- 6120

Fax:

(410) 328-5531

Education and Training

2007-2011 Bachelor of Science, Physiology, National University of Ireland, Galway, Ireland

2011-2015  PhD, Physiology, National University of Ireland, Galway, Ireland

2015-2019  Postdoctoral Fellowship, Shock, Trauma & Anesthesiology Research Center, University of Maryland, Baltimore, Baltimore, MD, United States

 

Highlighted Publications

 

  1. Henry RJ, Kerr DM, Finn DP, Roche M. FAAH-mediated modulation of TLR3-induced neuroinflammation in the rat hippocampus. J. Neuroimmunol.. 276(1-2), 126-34. PMID: 25245162. 2014.
  2. Lydon S, Healy O, Roche M. Salivary cortisol levels and challenging behavior in children with autism spectrum disorder. Research in Autism Spectrum Disorders. Research in Autism Spectrum Disorders. 10, 78-92. PMID: 25245162. 2015.
  3. Henry RJ, Kerr DM, Finn DP, Roche M. For whom the endocannabinoid tolls: Modulation of innate immune function and implications for psychiatric disorders. Prog. Neuropsychopharmacol. Biol. Psychiatry. 64, 167-80. PMID: 25794989. 2016.
  4. Barrett JP, Henry RJ, Villapol S, Stoica BA, Kumar A, Burns MP, Faden AI, Loane DJ. NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury. J Neuroinflammation. 14(1), 65. PMID: 28340575. 2017.
  5. Henry RJ, Kerr DM, Flannery LE, Killilea M, Hughes EM, Corcoran L, Finn DP, Roche M. Pharmacological inhibition of FAAH modulates TLR-induced neuroinflammation, but not sickness behaviour: An effect partially mediated by central TRPV1. Brain Behav. Immun.. 62, 318-331. PMID: 28237711. 2017.
  6. Flannery LE, Henry RJ, Kerr DM, Finn DP, Roche M. FAAH, but not MAGL, inhibition modulates acute TLR3-induced neuroimmune signaling in the rat, independent of sex. J. Neurosci. Res.. 96(6), 989-1001. PMID: 28726298. 2018.
  7. Ritzel RM, Doran SJ, Barrett JP, Henry RJ, Ma EL, Faden AI, Loane DJ. Chronic Alterations in Systemic Immune Function after Traumatic Brain Injury. J. Neurotrauma. 35(13), 1419-1436. PMID: 29421977. 2018.
  8. Sabirzhanov B, Faden AI, Aubrecht T, Henry R, Glaser E, Stoica BA. MicroRNA-711-Induced Downregulation of Angiopoietin-1 Mediates Neuronal Cell Death. J. Neurotrauma. 35(20), 2462-2481. PMID: 29774773. 2018.
  9. Henry RJ, Doran SJ, Barrett JP, Meadows VE, Sabirzhanov B, Stoica BA, Loane DJ, Faden AI. Inhibition of miR-155 Limits Neuroinflammation and Improves Functional Recovery After Experimental Traumatic Brain Injury in Mice. Neurotherapeutics. 16(1), 216-230. PMID: 30225790. 2019.
  10. Kumar A, Henry RJ, Stoica BA, Loane DJ, Abulwerdi G, Bhat SA, Faden AI. Neutral Sphingomyelinase Inhibition Alleviates LPS-Induced Microglia Activation and Neuroinflammation after Experimental Traumatic Brain Injury. J. Pharmacol. Exp. Ther.. 368(3), 338-352. PMID: 30563941. 2019.
  11. Doran SJ, Ritzel RM, Glaser EP, Henry RJ, Faden AI, Loane DJ. Sex Differences in Acute Neuroinflammation after Experimental Traumatic Brain Injury Are Mediated by Infiltrating Myeloid Cells. J. Neurotrauma. 36(7), 1040-1053. PMID: 30259790. 2019.
  12. Bhat SA, Henry RJ, Blanchard AC, Stoica BA, Loane DJ, Faden AI. Enhanced Akt/GSK-3β/CREB signaling mediates the anti-inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice. J. Neurochem.. e14954. PMID: 31926033. 2020.
  13. Barrett JP, Henry RJ, Shirey KA, Doran SJ, Makarevich OD, Ritzel RM, Meadows VA, Vogel SN, Faden AI, Stoica BA, Loane DJ. Interferon-β Plays a Detrimental Role in Experimental Traumatic Brain Injury by Enhancing Neuroinflammation That Drives Chronic Neurodegeneration. J. Neurosci.. 40(11), 2357-2370. PMID: 32029532. 2020.
  14. Henry RJ, Ritzel RM, Barrett JP, Doran SJ, Jiao Y, Leach JB, Szeto GL, Wu J, Stoica BA, Faden AI, Loane DJ. Microglial Depletion with CSF1R Inhibitor During Chronic Phase of Experimental Traumatic Brain Injury Reduces Neurodegeneration and Neurological Deficits. J Neurosci. 40(14), 2960-2974. PMID: 32094203. 2020.
  15. Henry RJ, Ritzel RM, Barrett JP, Doran SJ, Jiao Y, Leach JB, Szeto GL, Wu J, Stoica BA, Faden AI, Loane DJ. Microglial Depletion with CSF1R Inhibitor During Chronic Phase of Experimental Traumatic Brain Injury Reduces Neurodegeneration and Neurological Deficits. J. Neurosci.. 40(14), 2960-2974. PMID: 32094203. 2020.
  16. Doran SJ, Henry RJ, Shirey KA, Barrett JP, Ritzel RM, Lai W, Blanco JC, Faden AI, Vogel SN, Loane DJ. Early or Late Bacterial Lung Infection Increases Mortality After Traumatic Brain Injury in Male Mice and Chronically Impairs Monocyte Innate Immune Function. Crit. Care Med.. 48(5), e418-e428. PMID: 32149839. 2020.
  17. Sabirzhanov B, Makarevich O, Barrett J, Jackson IL, Faden AI, Stoica BA. Down-Regulation of miR-23a-3p Mediates Irradiation-Induced Neuronal Apoptosis. Int J Mol Sci. 21(10). PMID: 32456284. 2020.
  18. Henry RJ, Meadows VE, Stoica BA, Faden AI, Loane DJ. Longitudinal Assessment of Sensorimotor Function after Controlled Cortical Impact in Mice: Comparison of Beamwalk, Rotarod, and Automated Gait Analysis Tests. J. Neurotrauma. PMID: 32484024. 2020.
  19. Makarevich O, Sabirzhanov B, Aubrecht TG, Glaser EP, Polster BM, Henry RJ, Faden AI, Stoica BA. Mithramycin selectively attenuates DNA-damage-induced neuronal cell death. Cell Death Dis. 11(7), 587. PMID: 32719328. 2020.
  20. Henry RJ, Meadows VE, Stoica BA, Faden AI, Loane DJ. Longitudinal Assessment of Sensorimotor Function after Controlled Cortical Impact in Mice: Comparison of Beamwalk, Rotarod, and Automated Gait Analysis Tests. J Neurotrauma. 37(24), 2709-2717. PMID: 32484024. 2020.
  21. Khan NZ, Cao T, He J, Ritzel RM, Li Y, Henry RJ, Colson C, Stoica BA, Faden AI, Wu J. Spinal cord injury alters microRNA and CD81+ exosome levels in plasma extracellular nanoparticles with neuroinflammatory potential. Brain Behav Immun. 92, 165-183. PMID: 33307173. 2021.
  22. Henry RJ, Loane DJ. Targeting chronic and evolving neuroinflammation following traumatic brain injury to improve long-term outcomes: insights from microglial-depletion models. Neural Regen Res. 16(5), 976-977. PMID: 33229740. 2021.