Abid R. Bhat, PhD

2008–2013 B. Pharm., University of Kashmir, Kashmir, India
2014–2016 M. Pharm. (Pharmacology), Punjab Technical University, Kapurthala, India
2017–2021 Ph.D. (Pharmacy), JSS Academy of Higher Education & Research, Mysore, India
2018–2019 Postgraduate Diploma in Regulatory Toxicology, JSS Academy of Higher Education & Research, Mysore, India

Microparticles, Hyperbaric gas physiology, Neuropathology, Glymphatics

1. Bhat AR, Arya AK, Bhopale VM, Imtiyaz Z, Xu S, Bedir D, et al. Persistent neuroinflammation and functional deficits in a murine model of decompression sickness. J Appl Physiol. E-pub ahead of print April 25, 2024. doi:10.1152/japplphysiol.00097.2024
2. Thom SR, Bhopale VM, Bhat AR, Arya AK, Ruhela D, Qiao G, et al. Neuroinflammation with increased glymphatic flow in a murine model of decompression sickness. J Neurophysiol. 2023 Mar 1;129(3):662-671. doi: 10.1152/jn.00005.2023. Epub 2023 Feb 8
3. Imtiyaz Z, Bhopale VM, Arya AK, Bhat AR, Thom SR. Microparticles in human perspiration as an inflammatory response index. Diagnostics. 2024;14(12):1293. doi:10.3390/diagnostics14121293
4. Arya AK, Balestra C, Bhopale VM, Tuominen LJ, Sokolowski AR, Dugrenot E, L’Her E, Bhat AR, et al. Elevations of extracellular vesicles and inflammatory biomarkers in closed circuit SCUBA divers. Int J Mol Sci. 2023 Mar 22;24(6):5969. doi: 10.3390/ijms24065969
5. Thom SR, Bhopale VM, Arya AK, Ruhela D, Bhat AR, Mitra N, et al. Blood-borne microparticles are an inflammatory stimulus in type 2 diabetes mellitus. ImmunoHorizons. 2023;7(1):71-80. doi:10.4049/immunohorizons.2200099. 
6. Bhat A, Bishir M, Pandi-Perumal SR, Chang SL, Chidambaram SB. Roflumilast, a phosphodiesterase-4 inhibitor, ameliorates sleep deprivation-induced cognitive dysfunction in C57BL/6J mice. ACS Chem Neurosci. 2022 Jul;13(13):1938-1947. doi: 10.1021/acschemneuro.2c00127. 
7. Bhat A, Tan V, Heng B, Chow S, Basappa S, Essa MM, et al. Papaverine, a phosphodiesterase 10A inhibitor, ameliorates quinolinic acid-induced synaptotoxicity in human cortical neurons. Neurotox Res. 2021 Aug;39(4):1238-1250. doi: 10.1007/s12640-021-00368-4
8. Bhat A, Tan V, Heng B, Lovejoy DB, Sakharkar MK, Essa MM, et al. Roflumilast, a cAMP-specific phosphodiesterase-4 inhibitor, reduces oxidative stress and improves synapse functions in human cortical neurons exposed to the excitotoxin quinolinic acid. ACS Chem Neurosci. 2020 Dec 16;11(24):4405-4415. Epub 2020 Dec 1. doi:10.1021/acschemneuro.0c00636
9. Bhat A, Pires AS, Tan V, Babu Chidambaram S, Guillemin GJ. Effects of sleep deprivation on the tryptophan metabolism. Int J Tryptophan Res. 2020;13. doi:10.1177/1178646920970902
10. Bhat A, Ray B, Mahalakshmi AM, Tuladhar S, Nandakumar DN, Srinivasan M, et al. Phosphodiesterase-4 enzyme as a therapeutic target in neurological disorders. Pharmacol Res. 2020 Oct: 160:105078. doi: 10.1016/j.phrs.2020.105078
11. Bishir M, Bhat A, Essa MM, et al. Sleep deprivation and neurological disorders. BioMed Research International. 2020; 2020: 5764017. doi: 10.1155/2020/5764017
12. Chidambaram SB, Bhat A, Ray B, Sugumar M, Muthukumar SP, Manivasagam T, et al.  Cocoa beans improve mitochondrial biogenesis via PPARγ/PGC1α dependent signalling pathway in MPP+ intoxicated human neuroblastoma cells (SH-SY5Y). Nutr Neurosci. 2020;23(6):471-480. doi: 10.1080/1028415X.2018.1521088.