Academic Title:
Post Doc Fellow
Primary Appointment:
Surgery
Email:
Biosketch
Shafquat Azim, PhD, is a postdoctoral fellow in the Division of Surgical Sciences at the University of Maryland School of Medicine under Dr. Valeria R Mas. In her present position, she is exploring kidney transplantation focusing on the mechanism of kidney transplant tolerance and the effect of ischemia-reperfusion-injury (IRI) on graft functioning via epigenetic modifications. She is using techniques like CRISPR and single cell/nucleus RNA-seq to study the cause and consequences of kidney damage.
Research/Clinical Keywords
Transplantation research, kidney transplantation, single-cell RNA sequencing, operational tolerance, cell-free biomarkers, CRISPR-Cas9 mediated-knockout/methylation/demethylation, DNA methylation
Highlighted Publications
List of publications can be found on
https://www.ncbi.nlm.nih.gov/myncbi/shafquat.azim.1/bibliography/public/
May 16;S1600-6135(23)00466-5.
Anand S, Khan MA, Zubair H, Sudan SK, Vikramdeo KS, Deshmukh SK, Azim S, Srivastava SK, Singh S, Singh AP. MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming. EMBO Rep. 2023 Mar 6;24(3):e55643. doi: 10.15252/embr.202255643. Epub 2023 Jan 2. PubMed PMID: 36592158; PubMed Central PMCID: PMC9986821.
Lamanilao GG, Dogan M, Patel PS, Azim S, Patel DS, Bhattacharya SK, Eason JD, Kuscu C, Kuscu C, Bajwa A. Key hepatoprotective roles of mitochondria in liver regeneration. Am J Physiol Gastrointest Liver Physiol. 2023 Mar 1;324(3):G207-G218. doi: 10.1152/ajpgi.00220.2022. Epub 2023 Jan 17. Review. PubMed PMID: 36648139; PubMed Central PMCID: PMC9988520.
Zubair H, Azim S, Maluf DG, Mas VR, Martins PN. Contribution of Proteomics in Transplantation: Identification of Injury and Rejection Markers. Transplantation. 2023 Feb 23;. doi: 10.1097/TP.0000000000004542. [Epub ahead of print] PubMed PMID: 36814094.
Zubair H, Patel GK, Khan MA, Azim S, Zubair A, Singh S, Srivastava SK, Singh AP. Proteomic Analysis of MYB-Regulated Secretome Identifies Functional Pathways and Biomarkers: Potential Pathobiological and Clinical Implications. J Proteome Res. 2020 Feb 7;19(2):794-804. doi: 10.1021/acs.jproteome.9b00641. Epub 2020 Jan 27. PubMed PMID: 31928012; PubMed Central PMCID: PMC7700759.
Tyagi N, Deshmukh SK, Srivastava SK, Azim S, Ahmad A, Al-Ghadhban A, Singh AP, Carter JE, Wang B, Singh S. ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1. Mol Cancer Res. 2018 Feb;16(2):187-196. doi: 10.1158/1541-7786.MCR-17-0219. Epub 2017 Nov 8. PubMed PMID: 29117940; PubMed Central PMCID: PMC5805611.
Ahmad A, Azim S, Zubair H, Khan MA, Singh S, Carter JE, Rocconi RP, Singh AP. Epigenetic basis of cancer health disparities: Looking beyond genetic differences. Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):16-28. doi: 10.1016/j.bbcan.2017.01.001. Epub 2017 Jan 17. Review. PubMed PMID: 28108348; PubMed Central PMCID: PMC5513784.