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Erik R. Strauss, MD

Academic Title:

Associate Professor

Primary Appointment:

Anesthesiology

Email:

estrauss@som.umaryland.edu

Location:

UMMC, S11C00

Phone (Primary):

(410) 328-2752

Phone (Secondary):

(410) 328-9813

Fax:

(410) 328-3092

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Education and Training

2000-2004 B.S., Biology, University of Maryland Baltimore County
2004-2008 M.D., University of Maryland School of Medicine
2008-2009 Internship, Internal Medicine, Mercy Medical Center
2009-2012 Residency, Department of Anesthesiology, UMMC
2012-2013 Fellowship, Cardiothoracic Anesthesiology, UMMC
Faculty Appointments
2013-2022 Assistant Professor, Department of Anesthesiology, University of Maryland School of Medicine
2022-present Associate Professor, Department of Anesthesiology, University of Maryland School of Medicine

Research/Clinical Keywords

Blood Conservation Antifibrinolytic Therapy and Pharmacokinetics Cardiac Xenotransplantation Translational Research for Mitral Valve Repair

Highlighted Publications

  1. Strauss ER, Odonkor PN, Williams B, Choi S, Mueller J, Taylor B, Shah A, Goerlich CE, Mohiuddin MM, Griffith BP. Intraoperative Management of an Orthotopic Porcine-to-Human Cardiac Xenotransplant. Ann Thorac Surg. 115(3), 784-786. PMID: 36621667. 2023.
  2. Ghoreishi M, Chahal D, Shah A, Kang J, Hirsch J, Tran D, McCloskey D, Shkullaku M, Gupta A, Strauss ER, Dahi S, Taylor BS, Toursavadkohi S. First-in-Human Endovascular Aortic Root Repair (Endo-Bentall) for Acute Type A Dissection. Circ Cardiovasc Interv. 16(10), e013348. PMID: 37737022. 2023.
  3. Strauss E, Dahmane E, Judd M, Guo D, Williams B, Meyer M, Gammie JS, Taylor B, Mazzeffi MA, Gobburu JV, Tanaka KA. A Pharmacokinetic and Pharmacodynamic Investigation of an ε-Aminocaproic acid regimen designed for the context of cardiac surgery with cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 35(2), 406-417. PMID: 32811752. 2022.
  4. Shah A, Goerlich CE, Pasrija C, Hirsch J, Fisher S, Odonkor P, Strauss E, Ayares D, Mohiuddin MM, Griffith BP. Anatomical Differences Between Human and Pig Hearts and Their Relevance for Cardiac Xenotransplantation Surgical Technique. JACC Case Rep. 4(16), 1049-1052. PMID: 36062051. 2022.
  5. Strauss ER, Taneja M, Booth R, Sankova  S, Anders  Antifibrinolytics in Cardiac Surgery: What Is the Best Practice in 2022?. Curr Anesthesiol Rep. 12(4), 501-507. 2022.
  6. Odonkor P, Strauss E, Williams B. Ethical considerations during a pioneering surgical procedure: porcine cardiac xenotransplantation. Br J Hosp Med (Lond). 83(6), 1-7. PMID: 35787171. 2022.
  7. Tanaka KA, Henderson R, Thangaraju K, Morita Y, Mazzeffi MA, Strauss E, Katneni U, Buehler PW. In vitro effects of emicizumab on activated clotting time in blood samples from cardiac surgical patients. Haemophilia. 28(1), 183-190. PMID: 34735039. 2022.
  8. Strauss ER, Quinn RW, Pasrija C, Henderson R, Holmes SD, D'Ambra MN, Gammie JS. Intraoperative echocardiographic assessment of mitral valve translocation. Eur J Cardiothorac Surg. 62(2), ezac133. PMID: 35277715. 2022.
  9. Strauss ER, Odonkor PN, Williams B. Porcine Orthotopic Cardiac Xenotransplantation: The Role and Perspective of Anesthesiologists. J Cardiothorac Vasc Anesth. 36(8 Pt B), 2847-2850. PMID: 35537973. 2022.
  10. Mohiuddin MM, Goerlich CE, Singh AK, Zhang T, Tatarov I, Lewis B, Sentz F, Hershfeld A, Braileanu G, Odonkor P, Strauss E, Williams B, Burke A, Hittman J, Bhutta A, Tabatabai A, Gupta A, Vaught T, Sorrells L, Kuravi K, Dandro A, Eyestone W, Kaczorowski DJ, Ayares D, Griffith BP. Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months. Xenotransplantation. 29(3), e12744. PMID: 35357044. 2022.
  11. Mazzeffi MA, Henderson R, Powell E, Strauss E, Williams B, Tanaka K, Yang S , Deatrick K, Madathil R. Thrombopoietin, Soluble CD40 Ligand, and Platelet Count During Veno-arterial Extracorporeal Membrane Oxygenation. ASAIO J. 68(5), e77-e79. PMID: 34081052. 2022.
  12. Strauss ER, VanDyck K, Mazzeffi MA. Tranexamic acid for cesarean delivery: induction of a regimen for postpartum hemorrhage?. Am J Obstet Gynecol. S0002-9378((22), 00672-X. PMID: 35998746. 2022.
  13. Pasrija C, Quinn R, Strauss E, Wang L, Tran D, D'Ambra MN, Gammie JS. Translocation of the Mitral Valve in an Acute Large Animal Model. J Cardiovasc Transl Res. 15(5), 1100-1107. PMID: 35175554. 2022.
  14. Strauss ER, Li S, Henderson R, Carpenter R, Guo D, Thangaraju K, Katneni U, Buehler PW, Gobburu JV, Tanaka KA. A Pharmacokinetic and Plasmin-Generation Pharmacodynamic Assessment of a Tranexamic Acid Regimen Designed for Cardiac Surgery With Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. 36(8 Pt A), 2473-2482. PMID: 35094925. 2021.
  15. Chow JH, Strauss E, Mazzeffi MA. Angiotensin II and Vasoplegia in Cardiac Surgery: Paradigm Changer or Costly Contender?. J Cardiothorac Vasc Anesth. 35(1), 59-60. PMID: 32950345. 2021.
  16. Goerlich CE, Griffith B, Singh AK, Abdullah M, Singireddy S, Kolesnik I, Lewis B, Sentz F, Tatarov I, Hershfeld A, Zhang T, Strauss E, Odonkor P, Williams B, Tabatabai A, Bhutta A, Ayares D, Kaczorowski DJ, Mohiuddin MM. Blood Cardioplegia Induction, Perfusion Storage and Graft Dysfunction in Cardiac Xenotransplantation. Front Immunol. 12, 667093. PMID: 34177906. 2021.
  17. Henderson RA, Judd M, Strauss ER, Gammie JS, Mazzeffi MA, Taylor BS, Tanaka KA. Hematologic evaluation of intraoperative autologous blood collection and allogeneic transfusion in cardiac surgery. Transfusion. 61(3), 788-798. PMID: 33423288. 2021.
  18. Gammie JS, Quinn RW, Strauss ER, Wang L, D'Ambra MN, Hung J, Bernstein DA, Tran D, Rice MK, Holmes SD, Pasrija C. Initial Clinical Experience with Mitral Valve Translocation for Secondary Mitral Regurgitation. Ann Thorac Surg. S0003-4975(21), 00051-5. PMID: 33440174. 2021.
  19. Pasrija C, Quinn R, Bernstein D, Tran D, Alkhatid H, Rice M, Morales D, Shah A, Ghoreishi M, Strauss E, Henderson R, D'Ambra M, Gammie J. Mitral valve translocation: A novel operation for the treatment of secondary mitral regurgitation. The Annals of Thoracic Surgery. 112(6), 1954-1961. PMID: 34419436. 2021.
  20. Goerlich C, Singh A, Kaczorowski D, Abdullah M, Lewis B, Tatarov I, Hershfeld A, Zhang T, Strauss E, Odonkor P, Williams B, Ayares D, Griffith B, Mohiuddin M. The Use of Minimally Ischemic Cardiac Preservation Techniques to Overcome Perioperative Cardiac Xenograft Dysfunction (PCDX) in Life-Supporting Cardiac Xenotransplantation Model. Transplantation. 104(S3), S636. 2020.
  21. DiChiacchio L, Singh AK, Lewis B, Zhang T, Hardy N, Pasrija C, Morales D, Odonkor P, Strauss E, Williams B, Deatrick KB, Kaczorowski DJ, Ayares D, Griffith BP, Bartlett ST, Mohiuddin MM. Early experience with preclinical peri-operative cardiac xenograft dysfunction in a single program. Ann Thorac Surg. 109(5), 1357-1361. PMID: 31589847. 2020.
  22. Tanaka KA, Henderson RA, Strauss ER. Evolution of viscoelastic coagulation testing in the perioperative setting. Expert Rev Hematol. 13(7), 697-707. PMID: 32310702. 2020.
  23. Goerlich CE, Kaczorowski D, Singh A, Abdullah M, Lewis B, Zhang T, Tatarov I, Sentz F, Hershfeld A, Odonkor P, Williams B, Strauss E, Ayares D, Griffith B, Mohiuddin M. Human Thrombomodulin Transgene Expression Prevents Intracardiac Thrombus in Life Supporting Pig-to-Baboon Cardiac Xenotransplantation. J Heart Lung Transplant. 39(4), S145. 2020.
  24. Goerlich C, Singh A, Kaczorowski D, Abdullah M, Lewis B, Tatarov I, Hershfeld A, Zhang T, Strauss E, Odonkor P, Williams B, Ayares D, Griffith B, Mohiuddin M. Lack of Human Thrombomodulin Gene Expression in Life Supporting Pig-to-Baboon Cardiac Xenotransplantation Models Accelerate Antibody-Mediated Rejection. Transplantation. 104(S3), S635. 2020.
  25. Tanaka KA, Mondal S, Morita Y, Williams B, Strauss ER, Cicardi M. Perioperative Management of Patients With Hereditary Angioedema With Special Considerations for Cardiopulmonary Bypass. Anesth Analg. 131(1), 155-169. PMID: 32102012. 2020
  26. Abuelkasem E, Mazzeffi MA, Henderson RA, Wipfli C, Monroe A, Strauss ER, Chow JH, Tanaka KA. Clinical Impact of Protamine Titration-Based Heparin Neutralization in Patients Undergoing Coronary Bypass Grafting Surgery. J Cardiothorac Vasc Anesth. 33(8), 2153-2160. PMID: 30737123. 2019.
  27. Judd M, Strauss E, Hasan S, Abuelkasem E, Li J, Deshpande S, Mazzeffi MA, Ogawa S, Tanaka KA. Clotting time results are not interchangeable between EXTEM and FIBTEM on rotational thromboelastometry. J Cardiothorac Vasc Anesth. 34(6), 1467-1473. PMID: 32139339. 2019.
  28. Mazzeffi M, Strauss E, Meyer M, Hasan S, Judd M, Abuelkasem E, Chow J, Nandwani V, McCarthy P, Tanaka K. Coagulation Factor Levels and Underlying Thrombin Generation Patterns in Adult Extracorporeal Membrane Oxygenation Patients. Anesth Analg. 129(3), 659-666. PMID: 31425204. 2019.
  29. Strauss E, Tanaka K, Mazzeffi M. HAS-BLED-A Canary in Cardiac Surgery Bleeding?. J Cardiothorac Vasc Anesth. 33(6), 1607-1609. PMID: 30928287. 2019.
  30. Henderson RA, Mazzeffi MA, Strauss ER, Williams B, Wipfli C, Dawood M, Taylor BS, Tanaka KA. Impact of intraoperative high-volume autologous blood collection on allogeneic transfusion during and after cardiac surgery: a propensity score-matched analysis. Transfusion. 59(6), 2023-2029. PMID: 30882929. 2019.
  31. Pasrija C, Sawan MA, Sorensen E, Voorhees H, Shah A, Strauss E, Ton VK, DiChiacchio L, Kaczorowski DJ, Griffith BP, Pham SM, Kon ZN. Less invasive left ventricular assist device implantation may reduce right ventricular failure. Interact Cardiovasc Thorac Surg. 29(4), 592-598. PMID: 31326991. 2019.
  32. Morita Y, Strauss E, Tanaka KA. Low ACT After High-Dose Heparin: Is Hemodilution Best Option to Pass by Syclla and Charybdis?. A A Pract. 13(12), 479. PMID: 31633487. 2019.
  33. Mazzeffi M, Strauss E, Rabin J, Griffith B. Blunt Traumatic Injury to the Aortic Root and Aortic Valve. A A Pract. 10(3), 65-68. PMID: 29611823. 2018.
  34. DiChiacchio L, Singh A, Lewis B, Ayares D, Strauss E, Odonkor P, Williams B, Deatrick K, Kon Z, Mohiuddin M. Insights into the Development of a Life-Sustaining Orthotopic Cardiac Xenotransplant Model. Transplantation. 102(S315), DOI: 10.1097/01.tp.0000543037.39314.ef. 2018.
  35. Deshpande SP, Mazzeffi MA, Strauss E, Hollis A, Tanaka KA. Prostacyclins in Cardiac Surgery: Coming of Age. Semin Cardiothorac Vasc Anesth. 22(3), 306-323. PMID: 29277148. 2018.
  36. Odonkor P, Srinivas A, Strauss E, Williams B, Mazzeffi M, Tanaka KA. Perioperative Coagulation Management of a Hemophilia A Patient During Cardiac Surgery. Semin Cardiothorac Vasc Anesth. 21(4), 312-320. PMID: 28388863. 2017.
  37. Strauss ER, Mazzeffi MA, Williams B, Key NS, Tanaka KA. Perioperative management of rare coagulation factor deficiency states in cardiac surgery. Br J Anaesth. 119(3), 354-368. PMID: 28969316. 2017.
  38. Mazzeffi M, Lund L, Wallace K, Herrera AV, Tanaka K, Odonkor P, Strauss E, Rock P, Fiskum G. Effect of cardiopulmonary bypass on platelet mitochondrial respiration and correlation with aggregation and bleeding: a pilot study. Perfusion. 31(6), 508-15. PMID: 26916901. 2016.
  39. Mazzeffi MA, Stafford P, Wallace K, Bernstein W, Deshpande S, Odonkor P, Grewal A, Strauss E, Stubbs L, Gammie J, Rock P. Intra-abdominal Hypertension and Postoperative Kidney Dysfunction in Cardiac Surgery Patients. J Cardiothorac Vasc Anesth. 30(6), 1571-1577. PMID: 27590464. 2016.
  40. Strauss E, Taylor B, Mazzeffi M, Tanaka K, Odonkor P. The Auscultation of a Carbon Dioxide Embolization Event during Endoscopic Vein Harvest. Case Rep Anesthesiol. 2016, 6947679. PMID: 27340571. 2016.
  41. Mazzeffi M, Brown J, Bernstein W, Carter E, Lee IH, Strauss E. An Unusual Right Atrial Mass: A Misdiagnosis Identified by Intraoperative Transesophageal Echocardiography. J Cardiothorac Vasc Anesth. 30(1), 263-5. PMID: 26442454. 2015.
  42. Tanaka KA, Mazzeffi MA, Strauss ER, Szlam F, Guzzetta NA. Computational simulation and comparison of prothrombin complex concentrate dosing schemes for warfarin reversal in cardiac surgery. J Anesth. 30(3), 369-76. PMID: 26749482. 2015.

Additional Publication Citations

Book Articles/Chapters

Hensley’s Practical Approach to Cardiothoracic Anesthesia, Seventh Edition. Karsten Bartels, eds. 7th ed. Wolters Kluwer: Chapter 12. 2024 

Research Interests

 

Research Activities

2002-2003

Breast Cancer Undergraduate Research Experience (BCURE) Trainee          

Donald Creighton, PhD                               

Department of Biochemistry                       

University of Maryland, Baltimore, MD

2017-present

Mitral Translocation Project Team Member; PI: James Gammie, MD

Role: Intraoperative management and echocardiographer for the swine mitral surgery model, Primary Anesthesiologist and Echocardiographer for first 15 patients undergoing mitral translocation surgery at the University of Maryland. Intraoperative echocardiography guidance for atrial transseptal puncture device in development used on swine.

16-20 hours per month.

2017-present

Xenotransplant Team Member; PI: Muhammad Mohiuddin, MD

Role: Cardiac Anesthesiologist and Echocardiographer for Xenotransplantation Surgery. Orthotopic Pig Heart to Baboon Transplant.

8-16 hours per month.
 
    
 

Clinical Specialty Details

Cardiothoracic Anesthesiology, Transesophageal Echocardiography

Scope of Clinical Practice

2013-present

University of Maryland Medical Center, UM Capital Region Medical Center, University of Maryland School of Medicine, Baltimore, MD

Expertise: Cardiothoracic Anesthesiologist

Time Spent: 170 days/year

Patients: 400 cases per year

2017-present

University of Maryland School of Medicine, Baltimore, MD, United States

Expertise: Cardiac Anesthesiologist for Cardiac Xenotransplant Animal Lab Procedures (PI: Dr. Mohiuddin)

Role: Anesthetic and Critical Care of animal subjects (baboon and swine) undergoing cardiac surgery for research purposes. Echocardiographer

Time Spent: 10-15 hrs per month

Patients: 2-3 per month

Description: Modified anesthetic techniques for longest orthotopic cardiac xenotransplant transplant survivor (baboon) in North America.

2018-present

University of Maryland Medical Center, Baltimore, United States

Expertise: 2018 - present: MitraClip, HARPOON, and Percutaneous Mitral Valve Team

Role: Intraoperative TEE guidance and anesthetic management

Time Spent: 16 hours per month

Patients: 4-5 procedures per month

Description: Only non-cardiologist on the team regularly providing intraoperative transesophageal echocardiography guidance for catheter-based mitral valve repair and replacement procedures. I have been the primary educator regarding these procedures for the cardiothoracic anesthesiology fellows.

Awards and Affiliations

2003 Alpha Chi Honor Society
2004 Phi Beta Kappa Honor Society
2012 National Society of Collegiate Scholars
2013-present Member, American Society of Anesthesiologists
2013-present Member, Society of Cardiovascular Anesthesiologists

Grants and Contracts

Active Contracts
2021-present

(PI, No Salary; PI - Erik Strauss, MD)

Assessment of Transesophageal Echocardiography Probe Inertial Measurement and Post-operative Esophageal Dysfunction                                                                            I will be enrolling patients, conduct the study, collect and analyze data.

Award Total: $600.00
Completed Grants
7/1/2018-12/31/2020

(PI, No Salary; PI - Erik Strauss, MD)

Assessment of Tranexamic Acid and e-Aminocaproic Acid Pharmacokinetics and Therapeutics Effectiveness During Cardiopulmonary Bypass (TAPE)  SCA/IARS No Salary Support

Award Total: $50,000.00

Total Direct Cost: $50,000.00

Professional Activity

Institution - Departmental
2015-present Chair, Residency Clinical Competency Committee, Department of Anesthesiology, University of Maryland School of Medicine
2019-2020 Examiner for Mock Oral, Anesthesiology Residency, University of Maryland School of Medicine
Institutional Service
2021-2023 Faculty Senate Member, University of Maryland School of Medicine
National Service
2019-present Ad Hoc Reviewer, Seminars in Cardiothoracic and Vascular Anesthesia
2020-2021 Ad Hoc Reviewer, Current Anesthesiology Reports
2021-2023 Research Committee Member, Society of Cardiovascular Anesthesiologists
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