Update Your ProfileAcademic Title:
Associate Professor
Primary Appointment:
Orthopaedics
Secondary Appointment(s):
Epidemiology & Public Health
Email:
Phone (Primary):
(410) 328-9579
Education and Training
University of British Columbia, BComm, 2006
University of British Columbia, MHA, 2013
University of Amsterdam, PhD, 2021
Biosketch
My research focuses on empirical methods to improve the delivery of healthcare services, integrate patient preferences in clinical trial design, and reduce the socioeconomic consequences of orthopaedic injuries.
Research/Clinical Keywords
health economics; patient preferences; socioeconomic impacts; orthopaedic trauma; global health; clinical trials
Highlighted Publications
Major Extremity Trauma Research Consortium (METRC); O'Toole RV, Stein DM, O'Hara NN, Frey KP, Taylor TJ, Scharfstein DO, Carlini AR, Sudini K, Degani Y, Slobogean GP, Haut ER, Obremskey W, Firoozabadi R, Bosse MJ, Goldhaber SZ, Marvel D, Castillo RC. Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture. N Engl J Med. 2023 Jan 19;388(3):203-213.
O'Hara NN, Castillo RC, Carlini AR, Joshi M, Murray CK, Allen LE, Huang Y, Gary JL, Bosse MJ, Obremskey WT, McKinley TO, Schmidt AH, O'Toole RV; METRC. The Application of Bayesian Methods to Help Interpret the VANCO Trial Results. J Orthop Trauma. 2023 Jan 1;37(1):1-7.
PREP-IT Investigators. Aqueous skin antisepsis before surgical fixation of open fractures (Aqueous-PREP): a multiple-period, cluster-randomised, crossover trial. 2022 Oct 15;400(10360):1334-1344.
O'Hara NN. Eliciting Health Care Preferences With Discrete Choice Experiments. JAMA Netw Open. 2022 Apr 1;5(4):e228794.
Major Extremity Trauma Research Consortium (METRC), O'Toole RV, Joshi M, Carlini AR, Murray CK, Allen LE, Huang Y, Scharfstein DO, O'Hara NN, Gary JL, Bosse MJ, et al. Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial. JAMA Surg, 2021 Mar 24:e207259.
O’Hara NN, Slobogean GP, Klazinga NS, Kringos DS. Analysis of Patient Income in the 5 years following a Fracture Treated Surgically. JAMA Netwk Open, 2021 Feb 1;4(2):e2034898.
O’Hara NN, Kringos DS, Slobogean GP, Degani Y, Klazinga NS. Patients Place More of an Emphasis on Physical Recovery Than Return to Work or Financial Recovery. Clin Orthop Relat Res, 2021 Jun 1;479(6):1333-1343.
O’Hara NN, Isaac M, Slobogean GP, Klazinga NS. The socioeconomic impact of orthopaedic trauma: A systematic review and meta-analysis. PLoS One, 2020;15(1):e0227907.
O’Hara NN, Mugarura R, Potter J, Stephens T, Rehavi MM, Francois P, Blachut PA, O’Brien PJ, Mezei A, Beyeza T, Slobogean GP. The socioeconomic implications of isolated tibia and femur fracture from road traffic injuries in Uganda. J Bone Joint Surg Am. J Bone Joint Surg Am. 2018 Apr 4;100(7):e43.
Awards and Affiliations
2022 Top Podium Presentation, Bethune Round Table for International Surgery
Unreamed Intramedullary Nailing Versus External Fixation for the Treatment of Open Tibial Shaft Fractures in Uganda: A Randomized Clinical Trial
2022 Highlight Paper, Orthopaedic Trauma Association Annual Meeting
The Application of Bayesian Methods to Help Interpret the VANCO Trial Results
2020 Highlight Paper, Orthopaedic Trauma Association Annual Meeting
One-Year Results of a Prospective Randomized Controlled Trial of Operative Versus Nonoperative Fixation of Minimally Displaced Lateral Compression Pelvis Fractures: Secondary Analysis of Previously Reported Short-Term Results
2020 Bovil Award for Top Paper at the Orthopaedic Trauma Association Annual Meeting
Vitamin D3 Supplementation Does Not Improve Fracture Healing: A Double-Blinded Randomized Controlled Trial
2019 Highlight Paper, Orthopaedic Trauma Association Annual Meeting
A Prospective Clinical Trial Comparing Operative Versus Nonoperative Fixation of Minimally Displaced Lateral Compression Pelvic Fractures
2016 Highlight Paper, Orthopaedic Trauma Association Annual Meeting
Are large clinical trials justified?
2016 Orthopaedics Blue Ribbon Paper Award
Timing of hip fracture surgery & 30-day outcomes
2015 Highlight Paper, Orthopaedic Trauma Association Annual Meeting
Femoral neck shortening is associated with worse functional outcomes
Grants and Contracts
National Institutes of Health (1U01AR080377-01A1) - (Slobogean, PI)
HIP fracture Accelerated surgical TreaTment And Care tracK-2 (HIP ATTACK-2) trial
(Co-Investigator)
US Department of Defense (W81XWH-22-1-0863) - (Slobogean, PI)
Randomized Control Trial Comparing Antibiotic Cement Bead Pouch Versus Negative Pressure
Wound Therapy for the Management of Severe Open Tibia Fracture Wounds (VvB)
(Co-Investigator)
UMB Institute for Clinical & Translational Research (CENR22)
Understanding Financial Toxicity after Lower Extremity Trauma: A Collaborative Community-based Approach
(Principal Investigator)
National Institutes of Health (1R34AR082550-01 ) - (O'Hara & Slobogean, Co-PI)
A Planning Grant for a Multicenter Randomized Clinical Trial Comparing Hip Arthroplasty to Internal Fixation for Minimally Displaced Femoral Neck Fractures
US Department of Defense (W81XWH-22-1-0863) - (Slobogean, PI)
Randomized Control Trial Comparing Antibiotic Cement Bead Pouch Versus Negative Pressure
Wound Therapy for the Management of Severe Open Tibia Fracture Wounds (VvB)
(Co-Principal Investigator)
UMB Institute for Clinical & Translational Research (CENR22)
Understanding Financial Toxicity after Lower Extremity Trauma: A Collaborative Community-based Approach
(Principal Investigator)
Agency for Healthcare Research and Quality (1R03HS029699-01)
Is Aspirin a Cost-Effective Thromboprophylaxis Alternative for Orthopaedic Trauma Patients?
(Principal Investigator)
Agency for Healthcare Research and Quality (1R03HS027218-01A1)
The Economic Impact of Avoidable Healthcare-Associated Infections on Traumatic Extremity Fracture Patients
(Principal Investigator)
US Department of Defense (OR 190099) – (Pensy, PI)
Can Preoperative Skin Perfusion Predict Wound Healing Complications in High- Risk Peri-Articular Tibial Fracture Fixation
(Co-Investigator)
National Institutes of Health (NIAMS R01) – (Gitajn, PI)
Real-time fluorescence-based measurement of bone perfusion in post-traumatic infection
(Co-Investigator)
US Department of Defense (W81XWH1910848) – (O’Toole, PI)
Novel Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA-A Multicenter RCT
(Co-Investigator)
Osteosynthesis and Trauma Care Foundation – Research Grant
Psychosocial Recovery After Injury: Determining the Optimal Timing and Subgroups for Interventions
(Principal Investigator)
PCORI – Pragmatic Study (Slobogean, PI)
PREPARE: Pragmatic Randomized Trial Evaluating Preoperative Antiseptic Skin Solutions in Fractured Extremities
(Co-Investigator)
PCORI – Pragmatic Study (O'Toole, PI)
A Randomized Pragmatic Trial Comparing the Complications and Safety of Blood Clot Prevention Medicines Used in Orthopedic Trauma Patients
(Co-Investigator)