Scott E. Devine, PhD

1987-1993: Doctor of Philosophy, Molecular and Cell Biology, University of Maryland, Baltimore
1993-1999: Postdoctoral Fellow, Johns Hopkins University School of Medicine

Employment

2000-2009: Assistant Professor, Emory University School of Medicine
2009-present: Associate Professor, Dept. of Medicine and Institute for Genome Sciences, University of Maryland School of Medicine
2011-2021: Genome Biology Track Leader, Molecular Medicine Graduate Program

Scott Devine is a faculty member at the Institute for Genome Sciences (IGS) and an Associate Professor of Medicine at the University of Maryland School of Medicine in Baltimore, Maryland. He is primarily interested in germline and somatic human genome variation and how such variation affects human health (including cancers).

Human genome; genetic variation; mobile genetic elements; cancer genomics

Logsdon GA, Ebert P, Audano PA, Loftus M, Porubsky D, .....Devine SE, Shi X, Talkowski ME, Chaisson MJP, Dilthey AT, Konkel MK, Korbel JO, Lee C, Beck CR, Eichler EE, Marschall T. (2025). Complex genetic variation in nearly complete human genomes. bioRxiv [Preprint]. Sep 25:2024.09.24.614721. doi: 10.1101/2024.09.24.614721.  Accepted for publication in Nature.

Chuang NT, Gardner EJ, Terry DM, Crabtree J, Mahurkar AA, Rivell GL, Hong CC, Perry JA, Devine SE. (2021).  Mutagenesis of human genomes by endogenous mobile elements on a population scale.  Genome Res 31, 2225-22235.  PMID: 34772701.

Ebert P, Audano PA, Zhu Q, Rodriguez-Martin B, Porubsky D,.....Devine SE, Lee C, Korbel JO, Marschall T, Eichler EE. (2021).  Haplotype-resolved diverse human genomes and integrated analysis of structural variation.  Science 372, eabf7117.  PMID: 33632895.

Gardner EJ, Lam VK, Harris DN, Chuang NT, Scott EC, Pittard WS, Mills RE, 1000 Genomes Project Consortium, and Devine SE.  (2017).  The Mobile Element Locator Tool (MELT):  Population-scale mobile element discovery and biology.  Genome Res 27, 1916-1929.  Epub 2017 Aug 30.

Scott EC, Gardner EJ, Masood A, Chuang NT, Vertino PM, and Devine SE. (2016).  A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. Genome Res 26, 745-755. (Cover article).

Sudmant PH*, Raush T*, Gardner EJ*, Handsaker RE*, Abyzov A*, ....., Devine SE^#, Lee C^#, Eichler EE^#, and Korbel JO.^# (2015).  An integrated map of structural variation in 2,504 human genomes.  Nature 526, 75-81.   * Joint First Authors.  # Joint senior authors.

The 1000 Genomes Project Consortium (including Devine, S.E.) (2015) A global reference for human genetic variation.  Nature 526, 68-74.

The 1000 Genomes Project Consortium (including, Devine, S.E.) (2012) An integrated map of genetic variation from 1,092 human genomes.  Nature 491, 56-65.  

Iskow RC, McCabe MT, Mills RE, Torene S, Van Meir EG, Vertino PM, and Devine SE. (2010) Natural mutagenesis of human genomes by endogenous retrotransposons. Cell 141, 1253-1261.