October 15, 2018 | Joanne Morrison

Dr. Karen Kotloff Named Researcher of the Year; Dr. Steven Hanish, Dr. Thomas Scalea and Dr. Debora Stein Named Entrepreneurs of the Year for Liver Dialysis Device Called the Molecular Absorbent Recirculating System (MARS)
Several experts at the University of Maryland School of Medicine (UMSOM) received prestigious awards commemorating the University of Maryland Baltimore (UMB) 2018 Founders Week. Among them, Karen Kotloff, MD, Professor of Pediatrics, was named "Researcher of the Year" for her extensive work in infectious diseases in the U.S. and developing countries. The MARS team– Steven I. Hanish, MD, Visiting Associate Professor of Surgery, Thomas M. Scalea, MD, FACS, FCCM, The Honorable Francis X. Kelly Distinguished Professor in Trauma Surgery, and Deborah Stein, MD, MPH, FACS, FCCM, The R Adams Cowley, MD Professor in Shock and Trauma– were named "Entrepreneurs of the Year" for their liver dialysis device called the Molecular Absorbent Recirculating System (MARS).
Dr. Kotloff is Head of UMSOM's Division of Infectious Disease and Tropical Pediatrics and Associate Director of Clinical Studies for UMSOM's Center for Vaccine Development and Global Health (CVD). She has been instrumental in advancing the understanding of infectious pathogens and preventive and therapeutic interventions for children around the globe. She has spent her entire faculty career at UMSOM, starting in 1986, and serves as an advisor to the World Health Organization, the Gates Foundation, the Food and Drug Administration, and others. She is also a mentor of fellows and junior faculty members, including several who have now developed their own independent successful research careers at the school.
"Dr. Kotloff's work has been instrumental in setting policy and interventions around the world aimed at reducing childhood mortality," said UMSOM Dean E. Albert Reece, MD, PhD, MBA, who is also the Executive Vice president for Medical Affairs, UM Baltimore, and the John Z. and Akiko K. Bowers Distinguished Professor. "Her work is important not only to our community here in Baltimore, but to those in low resource settings around the world."
Drs. Hanish, Scalea and Stein's innovative application of MARS offers hope for those suffering with liver failure. This device can remove toxins, improve clotting and reduce brain swelling. The first use of MARS was at the R Adams Cowley Shock Trauma Center, where Dr. Scalea is also the Physician-In-Chief, Dr. Stein is Chief of Trauma and Dr. Hanish is a liver transplant surgeon.
Drs. Hanish, Scalea, and Stein have published the results of their life-saving work with the MARS in one of the largest studies to date, paving the way for other clinicians to use this device and affect countless lives.
Their results using MARS as a bridge to recovery and/or transplant also could serve as an important first step in gaining FDA approval for liver transplant recipients.
"Liver failure is a devastating disease that affects around 1,600 patients in the U.S. each year. With implementation of the MARS device, Drs. Hanish, Scalea and Stein have set an important path that will dramatically change the lives of those suffering from this terrible disease" said Dean Reece.
About the University of Maryland School of Medicine
Now in its third century, the University of Maryland School of Medicine was chartered in 1807 as the first public medical school in the United States. It continues today as one of the fastest growing, top-tier biomedical research enterprises in the world -- with 43 academic departments, centers, institutes, and programs; and a faculty of more than 3,000 physicians, scientists, and allied health professionals, including members of the National Academy of Medicine and the National Academy of Sciences, and a distinguished recipient of the Albert E. Lasker Award in Medical Research. With an operating budget of more than $1 billion, the School of Medicine works closely in partnership with the University of Maryland Medical Center and Medical System to provide research-intensive, academic and clinically-based care for more than 1.2 million patients each year. The School has over 2,500 students, residents, and fellows, and more than $530 million in extramural funding, with most of its academic departments highly ranked among all medical schools in the nation in research funding. As one of the seven professional schools that make up the University of Maryland, Baltimore campus, the School of Medicine has a total workforce of nearly 7,000 individuals. The combined School and Medical System ("University of Maryland Medicine") has an annual budget of nearly $6 billion and an economic impact more than $15 billion on the state and local community. The School of Medicine faculty, which ranks as the 8th highest among public medical schools in research productivity, is an innovator in translational medicine, with 600 active patents and 24 start-up companies. The School works locally, nationally, and globally, with research and treatment facilities in 36 countries around the world. Visit medschool.umaryland.edu
Contact
Department of Anesthesiology
(410) 328-6120 (phone)
(410) 328-5531 (fax)
newsletter@som.umaryland.edu
Joanne Morrison
Director of Marketing and Public Relations
University of Maryland School of Medicine
Related stories

Friday, May 17, 2024
Gov. Moore Signs Significant Funding Bills Securing the Future of Trauma Care for Marylanders
Dozens of Shock Trauma team members, trauma survivors, and supporters traveled to the state capital yesterday to support Maryland Governor Wes Moore, Senate President Bill Ferguson, and House Speaker Adrienne Jones as they signed a consequential bill into law expanding annual funding for Maryland’s renowned statewide trauma system. It will ensure access to world-class trauma care for Marylanders well into to the future.

Wednesday, July 20, 2022
University of Maryland School of Medicine Faculty Member Featured on NBC Nightly News Special Report on Gun Violence in America
A University of Maryland School of Medicine (UMSOM) faculty member was featured in a prestigious national news program over the weekend highlighting the lifesaving critical care medicine practiced at the R Adams Cowley Shock Trauma Center at the University of Maryland Medical Center (UMMC). In an extended segment called “One Night in America” that comprised half of the evening newscast for NBC Nightly News and additional coverage on MSNBC, a reporter was embedded in the trauma center from Saturday evening, July 16, into Sunday morning to document emergency trauma cases caused by gun violence. Reporters were also embedded in three other major cities showing different perspectives including police response to shootings and community support from a local street pastor.

Wednesday, January 19, 2022
World-Renowned University of Maryland School of Medicine Trauma Surgeon and Physician-Scientist Celebrates 25th Anniversary
As the Honorable Francis X. Kelly Distinguished Professor of Trauma Surgery and Director of the Program in Trauma at the University of Maryland School of Medicine (UMSOM) and Physician-in-Chief of the R Adams Cowley Shock Trauma Center at the University of Maryland Medical Center (UMMC), Thomas M. Scalea, MD, FACS, MCCM, has pioneered advances to trauma care for patients in the United States and around the world. He has cared for tens of thousands of Marylanders critically injured in motor vehicle collisions, falls and violent attacks, traveled to China and Haiti to render assistance to earthquake victims, helped train thousands of U.S. Air Force personnel and worked alongside military physicians in war-torn Afghanistan. He has steered Maryland’s highest-level trauma center through two years of the COVID-19 pandemic.

Thursday, December 16, 2021
Novavax COVID-19 Vaccine Found to be Safe and Effective in Phase 3 Trial Conducted by UM School of Medicine Researchers
An investigational COVID-19 vaccine made by Novavax was found to be 90 percent effective at preventing COVID-19 illness, according to results from a Phase 3 clinical trial published today in the New England Journal of Medicine. The University of Maryland School of Medicine’s (UMSOM) Center for Vaccine Development and Global Health served as one of the trial sites, and Karen Kotloff, MD, Professor of Pediatrics at UMSOM, served as Co-Chair for the trial protocol.

Thursday, August 06, 2020
Philanthropist and Real Estate Developer, Howard S. Brown Makes $2.5 Million Gift to UMSOM in Honor of Renowned Trauma Surgeon and Leader, Thomas M. Scalea, MD
Mr. Brown’s Gift Memorializes his Daughter, Esther Ann Brown Adler, and Establishes the Thomas M. Scalea, MD Endowed Distinguished Professorship in Trauma Surgery

Thursday, January 09, 2020
UM School of Medicine Research Shows Less Severe Cases of Diarrheal Illness can Still Lead to Child Deaths, Even Weeks Following Onset of the Illness
Diarrheal diseases are a leading cause of death for young children, accounting for nine percent of all deaths worldwide in children under five years of age, with most occurring in children under two years of age. Now, researchers at the University of Maryland School of Medicine (UMSOM) found that even milder cases of diarrheal diseases can lead to death in young children.

Monday, May 06, 2019
UM School of Medicine's Dr. Karen Kotloff Receives 2019 Alumni Achievement Award from Temple University
Karen Kotloff, MD, Professor of Pediatrics at the University of Maryland School of Medicine (UMSOM), has received the 2019 Alumni Achievement Award from the Lewis Katz School of Medicine at Temple University.

Friday, March 30, 2018
Stop the Bleed Team at Shock Trauma Center Trains Campus Leaders
The University of Maryland R Adams Cowley Shock Trauma Center provided special training today on methods to control bleeding as part of the “Stop the Bleed” campaign, a national effort to teach basic bleeding control.

Monday, September 11, 2017
Research Identifies Causes and Possible Treatments for Deadly Diseases Affecting Children in Developing Countries
University of Maryland School of Medicine Researchers Explore How to Prevent Diarrheal Diseases, a Leading Cause of Death in Young Children in Sub-Saharan Africa and South Asia

Wednesday, October 26, 2016
Researchers Develop System to Classify Gunshot Wounds and Other Similar Injuries to the Head
Every year, more than 32,000 Americans die from gunshot wounds. A significant proportion of these deaths involve head wounds. Despite this massive public health burden, researchers know little about the variables that determine whether a victim of these injuries will live or die.

Thursday, September 08, 2016
Largest-Ever Study to Compare Medications to Prevent Life-Threatening Clots in Orthopaedic Trauma Patients
Is the blood thinner heparin the most effective option to reduce the risk of blood clots for fracture patients? A comprehensive new study involving 13,000 patients, led by researchers at the University of Maryland School of Medicine (UM SOM), will try to resolve this important question.

Wednesday, June 29, 2016
UM SOM Researchers Awarded Grant to Use Innovative Alternative to Autopsies to Better Understand Child Mortality
Kathleen Neuzil, MD, MPH, director of the Center for Vaccine Development (CVD) at the University of Maryland School of Medicine (UM SOM), and UM SOM Dean E. Albert Reece, MD, PhD, MBA, announced today that CVD has been awarded a large grant from the Bill & Melinda Gates Foundation for research that will help determine why so many children under five are dying in the world’s poorest countries. The grant will fund use of an innovative alternative to traditional autopsy known as minimally invasive tissue sampling. The technique, which involves the collection of tissue samples with fine needles, allows researchers to quickly identify the cause of death, and help illuminate ways to save lives and improve the health of children in these vulnerable areas.

Thursday, May 26, 2016
Leading Surgeon Scientist and Trauma Chief Dr. Deborah Stein Invested as Inaugural R Adams Cowley Professor at the UM SOM
In a moving speech before a large audience recently at Westminster Hall, Deborah M. Stein, MD, MPH, newly invested as the R Adams Cowley, MD Professor in Shock and Trauma, used those words to reflect on her father’s influence and how proud he is to see the family’s legacy of healing continue. "Becoming a surgeon was all about my father -- I wanted to be him, and to heal with my hands, just as he had done."

Monday, January 04, 2016
R Adams Cowley Shock Trauma Center at the University of Maryland Showcased in Discovery Life Series - Shock Trauma: Edge of Life
Discovery Life’s new unscripted docudrama series Shock Trauma: Edge of Life follows a team of medical professionals at the world-renown University of Maryland R Adams Cowley Shock Trauma Center (“Shock Trauma” UM School of Medicine (SOM) faculty physicians and trauma surgeons, alongside University of Maryland Medical Center (UMMC) residents, fellows, nurses, patient care technicians, and an array of specialists, perform lifesaving medical care in the first and highest volume trauma center of its kind in the United States.