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NMR

Brief History:

The NMR center opened in October of 1996 with a 600 MHz NMR spectrometer in HSF I.  In August of 2003, specially designed space to receive this spectrometer and an additional 800 MHz spectrometer was made available.  In addition, cryoprobes were installed on both instruments once the spectrometers were in place.

Objectives of the UMB NMR shared facility:

The UMB NMR center will promote the use of Nuclear Magnetic Resonance Spectroscopy for use in research projects at the University of Maryland School of Medicine. The major objective of this center is to make sophisticated methods in NMR spectroscopy available to Principal Investigators at the University of Maryland, Baltimore in order to enhance their research efforts.

NMR Center Manager and Director: Dr. David J. Weber is the Director of the facility and Dr. Kristen Varney runs the day-to-day operation of the NMR facility that includes both 600 and 800 MHz spectrometers equipped with cryogenic probes.

NMR Committee: The NMR committee is chaired by Dr. David Weber and the members of the committee are Dr. Kristen Varney, Dr. Frank Margolis, Dr. John Hamlyn, and Dr. James Nataro.

Users Policies:

The Facility manager, Dr. Kristen Varney, oversees all of the users’ policies for data collection and scheduling NMR time. All investigators who wish to use the NMR facility are required to give information pertinent to their NMR usage to Dr. Varney. Authorization is required for all users who wish to operate the 600 or 800 MHz NMR spectrometers. Authorization will be given for use of higher field strengths only when it is demonstrated that data collection at the lower fields are insufficient. The facility manager will recommend this authorization to the committee chairman (Dr. Weber) prior to data collection. Dr. Varney keeps both NMR spectrometers in good working condition, trains users, manages the NMR facility billing and ordering, and performs NMR related research.

Satisfied Users:

  • Frank Margolis, PhD, Department of Anatomy and Neurobiology
  • Lindsay Black, PhD, Department of Biochemistry and Molecular Biology
  • James Nataro, MD, PhD, Department of Pediatrics
  • Mordecai Blaustein, PhD, Department of Physiology
  • Mary McKenna, PhD, Department of Pediatrics
  • John Hamlyn, PhD, Department of Physiology

Pricing:

800 MHz $9500/500 hrs
$2500/100 hrs
$80/individual hr
600 MHz $9500/667hrs
$2500/133hrs
$60/individual hr
Set-up fee $200 for 3hrs or less, $50/each additional hour
New Users 50 hr ($3000-4000) grant available to new users for set-up/optimization of promising new proteins

NMR time is scheduled in 24 hour (minimum) increments.

Updated pricing is always listed on the NMR facility website: http://medschool.umaryland.edu/nmr/.