Xiaoxuan Fan, PhD

1997  B.S., Biology, University of Science and Technology of China  

2000  M.S., Molecular Biology, Institute of Biophysics, Chinese Academy of Science

2006  Ph.D., Biochemistry and Molecular Biology, Pennsylvania State University

My interest in flow cytometry dated back to my Ph.D. research at Penn State University.  I used flow cytometry extensively in finding the novel bridging molecules between phagocytes and apoptotic cells in the process of phagocytosis.  After graduation in 2006, I went on to pursue a career in flow cytometry at Flow Cytometry Resource Center at Rockefeller University, where I had the opportunity to work on a broad range of applications in the cutting edge biomedical research, such as cell sorting of skin stem cells, immunophenotyping of dendritic cells.  In 2009, I joined Temple University, School of Medicine to set up a new flow cytometry core facility.  I helped investigators with experimental design, instrument operation and data analysis.  I also collaborated with investigators in their publications and grant applications.  I took the Director of Flow Cytometry Shared Service position at University of Maryland, School of Medicine in 2016.  I will continue to provide flow cytometry expertise to the university and update the researchers with new technology and instrumentation. 

Flow Cytometry, Cell Sorting

Fan X, Krahling S, Smith D, Williamson P, Schlegel RA. Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes. Mol. Biol. Cell 2004 Jun;15(6):2863-72.

St Laurent G, Shtokalo D, Dong B, Tackett MR, Fan X, Lazorthes S, Nicolas E, Sang N, Triche TJ, McCaffrey TA, Xiao W, Kapranov P. VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer. Genome Biol. 2013 Jul 22;14(7):R73.

Cornwell WD, Lewis MG, Fan X, Rappaport J, Rogers TJ. Effect of chronic morphine administration on circulating T cell population dynamics in rhesus macaques. J. Neuroimmunol. 2013 Dec 15;265(1-2):43-50.

Robinson RH, Meissler JJ, Fan X, Yu D, Adler MW, Eisenstein TK. A CB2-Selective Cannabinoid Suppresses T-Cell Activities and Increases Tregs and IL-10. J. Neuroimmune Pharmacol. 2015 Jun;10(2):318-32.

Meng L, Bai Z, He S, Mochizuki K, Liu Y, Purushe J, Sun H, Wang J, Yagita H, Mineishi S, Fung H, Yanik GA, Caricchio R, Fan X, Crisalli LM, Hexner EO, Reshef R, Zhang Y, Zhang Y. The Notch Ligand DLL4 Defines a Capability of Human Dendritic Cells in Regulating Th1 and Th17 Differentiation. J. Immunol. 2016 Feb 1;196(3):1070-80.

Cornwell WD, Wagner W, Lewis MG, Fan X, Rappaport J, Rogers TJ. Effect of chronic morphine administration on circulating dendritic cells in SIV-infected rhesus macaques. J. Neuroimmunol. 2016 Jun 15;295-296:30-40.