Areck A. Ucuzian, MD, PhD

Professional Training

Fellowship - Vascular Surgery; University of Pittsburgh Medical Center; Pittsburgh, PA

Residency - General Surgery;Loyola University Medical Center; Maywood,IL

Education

Loyola University Chicago; Maywood, IL

Ph.D.; Cell Biology, Neurobiology, and Anatomy

Tufts University School of Medicine; Boston, MA

M.D.; Medicine

Cornell University, Arts and Sciences; Ithaca, NY

B.A.; Cell/Molecular Biology

Dr. Ucuzian is a vascular surgeon and scientist, Assistant Professor of Surgery at the University of Maryland School of Medicine, and staff surgeon at the Baltimore Veterans Administration Medical Center.  He received his Bachelor of Arts at Cornell University, his Medical Degree at Tufts University, and his PhD from Loyola University Chicago. He completed general and vascular surgery training at Loyola University Medical Center and the University of Pittsburgh Medical Center, respectively.  He received the Robert W. Hobson, II, MD Early Career Investigator Award from the Council on Peripheral Vascular Disease of the American Heart Association.  He is funded by an NIH K08 and SVS Foundation/American College of Surgeons Mentored Clinical Scientist Research Career Development Award.  His research focuses on the molecular dysregulation associated with thoracic aortic dissection and aneurysm formation (TAAD), and the effect of exercise in modulating TAAD pathogenesis and patient quality of life. 

Aortic Disease Carotid Artery Disease Diabetic Foot Wounds Dialysis Access Surgery Limb Preservation Venous Disease

1. Pang Y, Wang X, Ucuzian AA, Brey EM, Burgess WH, Jones KJ, Alexander TD, Greisler HP. “Local Delivery of a Collagen-binding FGF-1 Chimera to Smooth Muscle Cells in Collagen Scaffolds for Vascular Tissue Engineering.” Biomaterials. 2010 Feb; 31(5): 878-885.
2. Ucuzian AA, Brewster LP, East AT, Pang Y, Gassman AA, Greisler HP. “Characterization of the Chemotactic and Mitogenic Response of SMCs to PDGF-BB and FGF-2 in Fibrin Hydrogels.” J Biomed Mater Res A. 2010 Sep; 94(3): 988-996.
3. Brewster LP, Ucuzian AA, Brey EM, Liwanag M, Samarel AM, Greisler HP. “FRNK Overexpression Limits the Depth and Frequency Of Vascular Smooth Muscle Cell Invasion in a Three-Dimensional Fibrin Matrix.” J Cell 2010 Nov; 225(2): 562-568.
4. Gassman AA, Kuprys T, Ucuzian AA, Brey E, Matsumura A, Pang Y, Larson J, Greisler HP. “Three Dimensional 10% Cyclic Strain Reduces Bovine Aortic Endothelial Cell Angiogenic Sprout Length and Augments Tubulogenesis in Tubular Fibrin Hydrogels.” J Tissue Eng Regen Med. 2011 May; 5(5): 375-383.
5. Ucuzian AA, Bufalino DV, Pang Y, Greisler HP. “Angiogenic Endothelial Cell Invasion into Fibrin is Stimulated by Proliferating Smooth Muscle Cell.” Microvascular Research. Nov 22; 90:40-7. Epub 2013 Jul 22.
6. Aicher BO, Mukhopadhyay S, Lu X, Muratoglu SC, Strickland DK, Ucuzian AA. “Quantitative micro-CT analysis of aortopathy in a mouse model of β-aminoproprionitrile-induced aortic aneurysm and dissection.” Journal of Visual Experimentation. 2018 Jul 16;(137).
7. Farivar BS, Toursavadkohi S, Monahan TS, Sharma J, Ucuzian AA, Kundi R, Sarkar R, Lal BK. “Prospective study of cryopreserved placental tissue wound matrix in the management of chronic venous leg ulcers.” J Vasc Surg Venous Lymphat Disord. 2019 Jan 6.
8. Yu D, Gernapudi R, Drucker C, Sarkar R, Ucuzian A, Monahan TS. “The myristoylated alanine-rich C kinase substrate differentially regulates kinase interacting with stathmin in vascular smooth muscle and endothelial cells and potentiates intimal hyperplasia formation.” J Vasc Surg. 2019 Mar 28.[Epub ahead of print]
9. Hosseini M, Sahajwani S, Zhang J, Toursavadkohi S, Ucuzian AA. Delayed stroke after hospitalization for COVID-19 pneumonia from common and internal carotid artery thrombosis. Journal of Vascular Surgery Cases and Innovative Techniques. 2020 Nov 10.
10. Aicher BO, Zhang J, Muratoglu S, Galisteo R, Arai AL, Gray VL, Lal BK, Strickland DK, Ucuzian AA. Moderate Aerobic Exercise Prevents Matrix Degradation and Death in a Mouse Model of Aortic Dissection and Aneurysm. American Journal of Physiology-Heart and Circulatory Physiology. 2021 Feb 26.