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Deborah M. Stein, MD, MPH

R Adams Cowley, MD Professor of Shock and Trauma

Academic Title:

Professor

Primary Appointment:

Surgery

Administrative Title:

Director of Critical Care Services

Phone (Primary):

410 328-3495

Education and Training

  • Cornell University, BA, 1993
  • Albert Einstein College of Medicine, MD, 1997
  • The Johns Hopkins University Bloomberg School of Public Health, MPH, 2004
  • Long Island Jewish Medical Center, Residency, 2002
  • R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Fellowship, 2003
  • R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Fellowship in Traumatology and Administrative Fellow, 2004

Biosketch

Deborah M. Stein MD, MPH, earned her Bachelor of Arts degree from Cornell University, her Medical Degree from Albert Einstein College of Medicine and her Master of Public Health from Johns Hopkins University Bloomberg School of Public Health with certificates in both Injury Control and Heath Policy. She completed her general surgery residency at Long Island Jewish Medical Center, Albert Einstein College of Medicine and a Fellowship in Trauma/Surgical Critical Care at the R Adams Cowley Shock Trauma Center at the University of Maryland School of Medicine. She is Board Certified in General Surgery, Surgical Critical Care and Neurocritical Care with additional Subspecialty Certification from the United Council for Neurologic Subspecialties in Neurocritical Care.  She is a fellow in the American College of Surgeons and the American College of Critical Care Medicine

Upon completion of her fellowship in 2004, Dr. Stein joined the faculty at the University of Maryland School of Medicine where she rose to become the R Adams Cowley Professor in Shock and Trauma in 2016.  Dr. Stein served in a number of roles at the R Adams Cowley Shock Trauma Center including Medical Director for Neurotrauma Critical Care, Medical Director for the Trauma Resuscitation Unit, Co-Director of the Neurotrauma Center for the State of Maryland, and as the Chief of Trauma at the R Adams Cowley Shock Trauma Center. In 2019, Dr. Stein was recruited to the position of Vice Chair of Trauma and Critical Care Surgery at the UCSF Department of Surgery and Chief of Surgery at Zuckerberg San Francisco General Hospital.  In the Fall of 2021, Dr. Stein rejoined the University of Maryland School of Medicine as Professor of Surgery with tenure and Director of Adult Critical Care Services for the University of Maryland Medical Center.

Dr. Stein has authored over 275 peer-reviewed articles and numerous book chapters. Her national service includes active participation in major trauma, critical care, and surgical societies including serving as the President for the Eastern Association for the Surgery of Trauma, Vice-Chair for the Trauma, Burn, and Surgical Critical Care Board of the American Board of Surgery and immediate past-Chair of the Research Committee for the American College of Surgeons’ Committee on Trauma.  She also serves as a Deputy Editor for the Journal of Trauma and Acute Care Surgery and is the Chair of the Certifying Exam Committee for the Trauma, Burns, and Surgical Critical Care Board.  Dr. Stein’s research interests are in the fields of traumatic brain injury, hemorrhagic shock, biomechanics of injury, and functional outcomes following traumatic injury.  She has been continuously federally funded over 20 years.   

Research/Clinical Keywords

Traumatic Brain Injury, Hemorrhagic Shock, Biomechanics of Injury

Highlighted Publications

Major Extremity Trauma Research Consortium (METRC); O'Toole RV, Stein DM, O'Hara NN, Frey KP, Taylor TJ, Scharfstein DO, Carlini AR, Sudini K, Degani Y, Slobogean GP, Haut ER, Obremskey W, Firoozabadi R, Bosse MJ, Goldhaber SZ, Marvel D, Castillo RC. Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture. N Engl J Med. 2023 Jan 19;388(3):203-213.

O'Toole RV, Stein DM, Frey KP, O'Hara NN, Scharfstein DO, Slobogean GP, Taylor TJ, Haac BE, Carlini AR, Manson TT, Sudini K, Mullins CD, Wegener ST, Firoozabadi R, Haut ER, Bosse MJ, Seymour RB, Holden MB, Gitajn IL, Goldhaber SZ, Eastman AL, Jurkovich GJ, Vallier HA, Gary JL, Kleweno CP, Cuschieri J, Marvel D, Castillo RC; METRC. PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients. BMJ Open. 2021 Mar 24;11(3):e041845.

Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O'Keeffe T, Rizoli S, Robinson BRH, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet J-F, Hoyt DB, Pearson GD, Leroux B, van Belle G for the PROPPR Study Group. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs. a 1:1:2 ratio and mortality in patients with severe trauma: The PROPPR Randomized Clinical Trial. JAMA. 2015;13(5):471-482.

Hsu CH, Haac BE, Drake M, Bernard AC, Aiolfi A, Inaba K, Hinson HE, Agarwal C, Galante J, Tibbits EM, Johnson NJ, Carlbom D, Mirhoseini MF, Patel MB, O'Bosky KR, Chan C, Udekwu PO, Farrell M, Wild JL, Young KA, Cullinane DC, Gojmerac DJ, Weissman A, Callaway C, Perman SM, Guerrero M, Aisiku IP, Seethala RR, Co IN, Madhok DY, Darger B, Kim DY, Spence L, Scalea TM, Stein DM. EAST Multicenter trial on targeted temperature management for hanging-induced cardiac arrest. J Trauma Acute Care Surg. 2018;85(1):37-47.

Stein DM, Braverman MA, Phuong J, Shipper E, Price MA, Bixby PJ, Adelson PD, Ansel BM, Cifu DX, DeVine JG, Galvagno SM, Gelb DE, Harris O, Kang CS, Kitagawa RS, McQuillan KA, Patel MB, Robertson CS, Salim A, Shutter L, Valadka AB, Bulger EM and the NTRAP Neurotrauma Panel Group. Developing a National Trauma Research Action Plan (NTRAP):  Results from the Neurotrauma Research Panel Delphi Survey.  J Trauma Acute Care Surg. 2022 May 1;92(5):906-915.

Hawryluk GWJ, Aguilera S, Buki A, Bulger E, Citerio G, Cooper DJ, Arrastia RD, Diringer M, Figaji A, Gao G, Geocadin R, Ghajar J, Harris O, Hoffer A, Hutchinson P, Joseph M, Kitagawa R, Manley G, Mayer S, Menon DK, Meyfroidt G, Michael DB, Oddo M, Okonkwo D, Patel M, Robertson C, Rosenfeld JV, Rubiano AM, Sahuquillo J, Servadei F, Shutter L, Stein D, Stocchetti N, Taccone FS, Timmons S, Tsai E, Ullman JS, Vespa P, Videtta W, Wright DW, Zammit C, Chesnut RM. A management algorithm for patients with intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med. 2019 Dec;45(12):1783-1794.

Chesnut R, Aguilera S, Buki A, Bulger E, Citerio G, Cooper DJ, Arrastia RD, Diringer M, Figaji A, Gao G, Geocadin R, Ghajar J, Harris O, Hoffer A, Hutchinson P, Joseph M, Kitagawa R, Manley G, Mayer S, Menon DK, Meyfroidt G, Michael DB, Oddo M, Okonkwo D, Patel M, Robertson C, Rosenfeld JV, Rubiano AM, Sahuquillo J, Servadei F, Shutter L, Stein D, Stocchetti N, Taccone FS, Timmons S, Tsai E, Ullman JS, Vespa P, Videtta W, Wright DW, Zammit C, Hawryluk GWJ. A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med. 2020 May;46(5):919-929.

Hawryluk GWJ, Selph S, Lumba-Brown A, Totten AM, Ghajar J, Aarabi B, Ecklund J, Shackelford S, Adams B, Adelson D, Armonda RA, Benjamin J, Boone D, Brody D, Dengler B, Figaji A, Grant G, Harris O, Hoffer A, Kitigawa R, Latham K, Neal C, Okonkwo DO, Pannell D, Rosenfeld JV, Rosenthal G, Rubiano A, Stein DM, Stippler M, Talbot M, Valadka A, Wright DW, Davis S, Bell R. Rationale and Methods for Updated Guidelines for the Management of Penetrating Traumatic Brain Injury.  Neurotrauma Rep. 2022 Jun 21;3(1):240-247. doi: 10.1089/neur.2022.0008. eCollection 2022.PMID: 35919507

Stein DM, Kozar RA, Livingston DH, et al; AAST Geriatric Trauma/ACS Committee. Geriatric traumatic brain injury-What we know and what we don’t. J Trauma Acute Care Surg. 2018;85(4):788-798.

Ghneim M, Albrecht J, Brasel K, Knight A, Liveris A, Watras J, Michetti CP, Haan J, Lightwine K, Winfield RD, Adams SD, Podbielski J, Armen S, Zacko JC, Nasrallah FS, Cooper Z, Stein DM, Geri-TBI Study Group.  Factors associated with receipt of intracranial pressure monitoring in older adults with traumatic brain injury.  TASCO. 2021;6:e000733.  

Ghneim M, Brasel K, Vesselinov R, Albrecht J, Liveris A, Watras J, Michetti C, Haan J, Lightwine K, Winfield R, Adams S, Podbielski J, Armen S, Zacko JC, Nasrallah F, Schaffer K, Dunn J, Smoot B, Schroeppel T, Stillman Z, Cooper Z, Stein D; Additional Study Group Members of The American Association for the Surgery of Trauma Geri-TBI Study. Traumatic Brain Injury in Older Adults: Characteristics, Outcomes, and Considerations. Results From the American Association for the Surgery of Trauma Geriatric Traumatic Brain Injury (GERI-TBI) Multicenter Trial. J Am Med Dir Assoc. 2022 Apr;23(4):568-575.e1.

Joseph B, Saljuqi AT, Amos JD, Teichman A, Whitmill ML, Anand T, Hosseinpour H, Burruss SK, Dunn JA, Najafi K, Godat LN, Enniss TM, Shoultz TH, Egodage T, Bongiovanni T, Hazelton JP, Colling KP, Costantini TW, Stein DM, Schroeppel TJ, Nahmias J; AAST Frailty MIT Study Group. Prospective Validation and Application of the Trauma Specific Frailty Index (TSFI): Results of an AAST Multi-Institutional Observational Trial.  J Trauma Acute Care Surg. 2022 Oct 17. doi: 10.1097/TA.0000000000003817. Online ahead of print.  PMID: 36279368

Additional Publication Citations

A complete list of Dr. Stein's publications can be found on PubMed

Research Interests

Dr. Stein's research interests are in the fields of traumatic brain injury, hemorrhagic shock, biomechanics of injury, and functional outcomes following traumatic injury. She is currently Principal Investigator for multiple federally funded grants.

Grants and Contracts

Genomics-Based Diagnosis in Patients at Risk for Poor Outcome after Traumatic Brain Injury
Stein (Co-PI; Fiskum, Kozar, Fraser Co-PIs)
Air Force Office of Scientific Research
Total Direct Costs: $965,079

The Community of Trauma Care – Partnering with Patients and Caregivers to Improve Injury Outcomes (PCORI-TSN)
Stein (PI)
Total Direct Costs: $198,733

National Trauma Research Action Plan (NTRAP)
Coalition for National Trauma Research/Depatment of Defense
Total Direct Costs: $45,238.82

Crash Injury Research and Engineering Network (CIREN) Pedestrian and Motor Vehicle Occupant Enrollment

National Highway Traffic Safety Administration (NHTSA)

Total Direct Cost: $450,367