Kristin A. Maloney, MS, MGC

B.S., Biology, The College of New Jersey, 2003

M.S., Genetics & Genomics, Duke University, 2009

M.G.C. (Masters in Genetic Counseling), University of Maryland School of Medicine, 2012

C.G.C. (Certification from the American Board of Genetic Counseling), 2012, 2017

As a board-certified and licensed genetic counselor and faculty member in the Department of Medicine at the University of Maryland School of Medicine (UM-SOM), my work integrates clinical practice, teaching, research, and laboratory genetic counseling. My research is centered on monogenic diabetes, a heterogeneous group of rare conditions often mistaken for common diabetes types, with an overall goal of increasing understanding of monogenic diabetes and refining the accuracy of genetic diagnostics.  I have significant experience in the crucial step of genetic result disclosure within research settings, including the Personalized Diabetes Medicine Program (PDMP) and the ongoing Rare and Atypical Diabetes Network (RADIANT) study, as well as in my clinical role at the University of Maryland Medical Center for Diabetes and Endocrinology.  I am also a lead variant biocurator for the ClinGen Monogenic Diabetes Expert Panel (MDEP), where I have spent the last seven years refining the application of ACMG/AMP guidelines to the primary monogenic diabetes genes (HNF1A, HNF4A, GCK, HNF1B). Additionally, I co-chair the Genetics Discovery team for the RADIANT study, where I oversee genomic data analysis and provide expertise in evaluating gene-disease associations and variant pathogenicity.   Additionally, I oversee a variant interpretation rotation in the Master's in Genetic Counseling (MGC) program, in addition to my role as Assistant Director for Student Research.  I have a general interest in personalized medicine, including pharmacogenomics, and serve on the Pharmacogenetics Subcommittee on the P&T committee in the hospital.

personalized medicine, pharmacogenomics, monogenic diabetes, genetic counseling, variant interpretation

Maloney, K.A., Mizerik, E., King, R.H., McGinnis, E., Perkowitz, S., Diamonstein, C., Schmanski, A., Saliganan, S., Shipper, A., Udler, M., Guan, Y., Pollin, T.I. (2023). Genetic Counseling in Diabetes Mellitus: A Practice Resource of the National Society of Genetic Counselors. Journal of Genetic Counseling,10.1002/jgc4.1744. Advance online publication. https://doi.org/10.1002/jgc4.1744

Murphy, R., Colclough, K., Pollin, T.I., Ikle, J.M., Svalastoga, P., Maloney, K.A., et al. (2023). A Systematic Review of the use of Precision Diagnostics in Monogenic Diabetes. Communications Medicine, 3(1), 136. https://doi.org/10.1038/s43856-023-00369-8

Lynch, M. T., Maloney, K. A., Pollin, T. I., Streeten, E. A., Xu, H., Regeneron Genetics Center, Shuldiner, A. R., Van Hout, C. V., Gonzaga-Jauregui, C., & Mitchell, B. D. (2021). The burden of pathogenic variants in clinically actionable genes in a founder population. American Journal of Medical Genetics Part A, 185(11), 3476–3484. https://doi.org/10.1002/ajmg.a.62472

Mills, R.A., Eichmeyer, J.N., Williams, L.M., Muskett, J.A., Schmidlen, T.J., Maloney, K.A., Lemke, A.A. (2018). Patient care situations benefitting from pharmacogenomic testing. Current Genetic Medicine Reports, 6, 43-S1.

Perry, C.G., Maloney, K.A., Beitelshees, A.L., Jeng, L.J., Ambulos Jr., N.P., Shuldiner, A.R., and Blitzer, M.G. (2016). Educational innovations in clinical pharmacogenomics. Clinical Pharmacology & Therapeutics, 99(6), 582-584.