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2013

  1. Adib-Samii P, Rost N, Traylor M, Devan W, Biffi A, Lanfranconi S, Fitzpatrick K, Bevan S, Kanakis A, Valant V, Gschwendtner A, Malik R, Richie A, Gamble D, Segal H, Parati EA, Ciusani E, Holliday EG, Maguire J, Wardlaw J, Worrall B, Bis J, Wiggins KL, Longstreth W, Kittner SJ, Cheng YC, Mosley T, Falcone GJ, Furie KL, Leiva-Salinas C, Lau BC, Saleem Khan M; Australian Stroke Genetics Collaborative; Wellcome Trust Case-Control Consortium-2 (WTCCC2); METASTROKE, Sharma P, Fornage M, Mitchell BD, Psaty BM, Sudlow C, Levi C, Boncoraglio GB, Rothwell PM, Meschia J, Dichgans M, Rosand J, Markus HS; International Stroke Genetics Consortium.  17q25 locus is associated with white matter hyperintensity lesion volume in patients with ischemic stroke, but not with lacunar stroke.  Stroke 44(6):1609-15, 2013.  PMID 23674528.
  2. Capuano MM, Sorkin JD, Chang Y-PC, Ling H, O'Connell JR, Rothman PB, Mitchell BD, Silver KD. Polymorphisms in the SOCS7 gene and glucose homeostasis traits.  BMC Res Notes 1:235, 2013.  PMCID3686602.
  3. den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dörr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson A, Junttila J, Kääb S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Leach IM, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, M Vuml Ller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp S, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T, Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Jarvelin MR, Jula A, Kähönen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtimäki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widen E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L; Global BPgen Consortium; CARDIoGRAM Consortium, Erdmann J, Thompson JR; PR GWAS Consortium, Pfeufer A; QRS GWAS Consortium, Sotoodehnia N; QT-IGC Consortium, Newton-Cheh C; CHARGE-AF Consortium, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ.  Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.   Nat Genet 45(6):621-31, 2013.  PMID: 23583979
  4. Ferguson JF, Matthews GJ, Townsend RR, Raj D, Kanetsky PA, Budoff M, Fischer MJ, Rosas S, Kanthety R, Ojo A, Rahman M, He J, Go A,  Gadegbeku C, Flack J, Wright J, Master S, Qasim A, Li M, Mehta NN, Shen H, Mitchell BD, O’Connell JR, Shuldiner AR, Ho WK, Young R, Rasheed A, Danesh J, Saleheen D, Kusek J,  Feldman HI, Rader DJ, Foulkes AS, Reilly MP, CRIC Study Investigators. Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort Study.  J Amer Coll Cardiol (in press).  PMID:23727086
  5. Ganesh SK, Tragante V, Guo W, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, Gaunt TR, Gho JM, Gieger C, Gong Y, Isaacs A, Kleber ME, Leach IM, McDonough CW, Meijs MF, Mellander O, Molony CM, Nolte IM, Padmanabhan S, Price TS, Rajagopalan R, Shaffer J, Shah S, Shen H, Soranzo N, van der Most PJ, Van Iperen EP, van Setten J, Vonk JM, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Boer JM, Boerwinkle E, Burkley B, Burt A, Chakravarti A, Chen W, Cooper-Dehoff RM, Curtis SP, Dreisbach A, Duggan D, Ehret GB, Fabsitz RR, Fornage M, Fox E, Furlong CE, Gansevoort RT, Hofker MH, Hovingh GK, Kirkland SA, Kottke-Marchant K, Kutlar A, Lacroix AZ, Langaee TY, Li YR, Lin H, Liu K, Maiwald S, Malik R; METASTROKE, Murugesan G, Newton-Cheh C, O'Connell JR, Onland-Moret NC, Ouwehand WH, Palmas W, Penninx BW, Pepine CJ, Pettinger M, Polak JF, Ramachandran VS, Ranchalis J, Redline S, Ridker PM, Rose LM, Scharnag H, Schork NJ, Shimbo D, Shuldiner AR, Srinivasan SR, Stolk RP, Taylor HA, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Winkelmann BR, Wyatt S, Young JH, Boehm BO, Caulfield MJ, Chasman DI, Davidson KW, Doevendans PA, Fitzgerald GA, Gums JG, Hakonarson H, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W; LifeLines Cohort Study, März W, Mitchell BD, Murray SS, Oldehinkel AJ, Rader DJ, Reilly MP, Reiner AP, Schadt EE, Silverstein RL, Snieder H, Stanton AV, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Johnson AD, Munroe PB, de Bakker PI, Zhu X, Levy D, Keating BJ, Asselbergs FW.  Loci influencing blood pressure identified using a cardiovascular gene-centric array.  Hum Mol Genet 22(8):1663-78, 2013. 
  6. Guo Y, Lanktree MB, Taylor K, Hakonarson H, Lange LA, Keating BJ; IBC 50K SNP array BMI Consortium.  Gene-centric meta-analysis of 108,912 individuals confirm known body mass index loci and reveal three novel signals.  Hum Molec Genet 22(1): 184-201, 2013. PMCID3522401.
  7. Hairston KG, Ducharme JD, Treuth MS, Hsueh W-C, Jastreboff AM, Ryan KA, Shi X, Mitchell BD, Shuldiner AR, Snitker S.  Comparison body composition and physical activity between Old Order Amish children and non-Amish children.  Diabetes Care 36(4):873-9, 2013.  PMCID3609522.
  8. Hamedani AG, Cole JW, Cheng Y, Sparks MJ, O’Connell JR, Stine OC, Wozniak MA, Stern BJ, Mitchell BD, Kittner SJ. Factor V Leiden and ischemic stroke: the Genetics of Early Onset Stroke (GEOS) Study.  J Stroke Cerebrovasc Dis 22(4):419-23, 2013.  PMCID3288467.
  9. Harriott AM, Dueker N, Cheng Y-C, Ryan KA, O’Connell JR, Stine OC, McArdle PF, Wozniak MA, Stern BJ, Mitchell BD, Kittner SJ, Cole JW. Polymorphisms in migraine-associated gene, ATP1A2, and ischemic stroke risk in a biracial population: The Genetics of Early Onset Stroke Study.  SpringerPlus 2:46, 2013.  PMCID3582818.
  10. Hochberg MC, Yerges-Armstrong L, Yau M, Mitchell BD.  Genetic epidemiology of osteoarthritis: Recent developments and future directions.  Curr Opin Rheumatol 25(2):192-97, 2013.
  11. Horenstein RB, Mitchell BD, Post WS, Leutjohann D, von Bergmann K, Ryan KA, Terrin M, Shuldiner AR, Steinle NI.  The ABCG8 G574R variant, serum plant sterol levels, and cardiovascular disease risk in the Old Order Amish.  Arterioscl Thromb Vasc Biol 33:413-9, 2013.
  12. Jahanshad N, Kochunov P, Sprooten E, Mandl RC, Nichols TE, Almasy L, Blangero J, Brouwer RM, Curran JE, de Zubicaray GI, Duggirala R, Fox PT, Hong LE, Landman BA, Martin NG, McMahon KL, Medland SE, Mitchell BD, Olvera RL, Peterson CP, Starr JM, Sussmann JE, Toga AW, Wardlaw JM, Wright MJ, Hulshoff Pol HE, Bastin ME, McIntosh AM, Deary IJ, Thompson PM, Glahn DC.  Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI Working Group.  NeuroImage (in press)
  13. Koller DL, Zheng H-F, Karasik D, Yerges-Armstrong L, Liu C-T, McGuigan F, Kemp JP, Giroux S, Lai D, Edenberg HJ, Peacock M, Czerwinski S, McMahon G, St Pourcain B, Timpson NJ, Lawlor DA, Evans DM, Towne B, Blangero J, Carless M, Kammerer C, Goltzman D, Kovacs C, Prior J, Rousseau F, Tobias JH, Akesson K, Econs MJ, Mitchell BD, Richards JB, Kiel DP, Foroud T. Meta-analysis of genome-wide studies identifies Wnt16 and esr1SNPs associated with bone mineral density in premenopausal women.  J Bone Miner Res 28(3):547-58, 2013.
  14. Lewis JP, Horenstein RB, Ryan R, O’Connell JR, Gibson Q, Mitchell BD, Tanner K, Chai S, Bliden KP, Tantry US, Peer CJ, Figg WD, Spencer SD, Pacanowski MA, Gurbel PA, Shuldiner AR.  The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response.  Pharmacogenet Genomics 23(1): 1-8, 2013.  PMC3682407.
  15. Lewis JP, Ryan K, O'Connell JR, Horenstein RB, Damcott CM, Gibson Q, Pollin TI, Mitchell BD, Beitelshees AL, Pakzy R, Tanner K, Parsa A, Tantry US, Bliden KP, Post WS, Faraday N, Herzog W, Gong Y, Pepine CJ, Johnson JA, Gurbel PA, Shuldiner AR.  Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes.  Circulation: Cardiovasc Genet (in press).
  16. Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Böhringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gögele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Räikkönen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, H Vermeulen S, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S.  A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.  PLOS Genetics 9(2):e1003266, 2013.  PMCID3567175.
  17. Raheja UK, Stephens SH, Mitchell BD, Rohan KJ, Vaswani D, Balis TG, Nijjar GV, Sleemi A, Pollin TI, Ryan K, Reeves GM, Weitzel N, Morrissey M, Yousufi H, Langenberg P, Shuldiner AR, Postolache TT. Seasonality of mood and behavior in the Old Order Amish.  J Affect Dis 147: 112-7, 2013.  PMCID3606685.
  18. Snitker S, Xie K, Ryan KA; Yu D, Shuldiner AR, Mitchell BD, Gong D-W.  Correlation of circulating MMP-9 with white blood cell count in humans: effect of smoking.  PLoS One (in press)
  19. Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, Viikari J, Lohman KK, Ferrucci L, Melhus H, Ingelsson E, Byberg L, Lind L, Lorentzon M, Salomaa V, Campbell H, Dunlop M, Mitchell BD, Herzig KH, Pouta A, Hartikainen AL; Genetic Investigation of Anthropometric Traits (GIANT) consortium, Streeten EA, Theodoratou E, Jula A, Wareham NJ, Ohlsson C, Frayling TM, Kritchevsky SB, Spector TD, Richards JB, Lehtimäki T, Ouwehand WH, Kraft P, Cooper C, März W, Power C, Loos RJ, Wang TJ, Järvelin MR, Whittaker JC, Hingorani AD, Hyppönen E.  Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.  PLoS Medicine 10(2):e1001383, 2013.  PMCID3564800.
  20. Williams FM, Carter AM, Hysi PG, Surdulescu G, Hodgkiss D, Soranzo N, Traylor M, Bevan S, Dichgans M, Rothwell PM, Sudlow C, Farrall M, Silander K, Kaunisto M, Wagner P, Saarela O, Kuulasmaa K, Virtamo J, Salomaa V, Amouyel P, Arveiler D, Ferrieres J, Wiklund PG, Arfan Ikram M, Hofman A, Boncoraglio GB, Parati EA, Helgadottir A, Gretarsdottir S, Thorsteinsdottir U, Thorleifsson G, Stefansson K, Seshadri S, Destefano A, Gschwendtner A, Psaty B, Longstreth W, Mitchell BD, Cheng YC, Clarke R, Ferrario M, Bis JC, Levi C, Attia J, Holliday EG, Scott RJ, Fornage M, Sharma P, Furie KL, Rosand J, Nalls M, Meschia J, Mosely TH, Evans A, Palotie A, Markus HS, Grant PJ, Spector TD; EuroCLOT Investigators, the Wellcome Trust Case Control Consortium 2, MOnica Risk Genetics, MetaStroke, and the International Stroke Genetics Consortium.  Ischaemic stroke is associated with the ABO locus: the EUROCLOT study.  Ann Neurol 73(1):16-31, 2013.  PMCID3582024.
  21. Zheng HF, Duncan EL, Yerges-Armstrong LM, Eriksson J, Bergström U, Leo PJ, Leslie WD, Goltzman D, Blangero J, Hanley DA, Carless MA, Streeten EA, Lorentzon M, Brown MA, Spector TD, Pettersson-Kymmer U, Ohlsson C, Mitchell BD, Richards JB.  Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm.  J Med Genet 50(7):473-8, 2013.  PMID 23572186

In press:

  1. Kochunov P, Charlesworth J, Winkler A, Hong LE, Nichols T, Curran JE,  Sprooten E. Jahanshad N, Thompson PM, Johnson MP,  Kent JW Jr., Landman B,  Mitchell BD, Cole SA, Dyer TD, Moses EK, Goring H, Almasy L, Duggirala R, Olvera RL, Glahn D, Blangero J. Transcriptomics of cortical gray matter thickness decline during aging.  NeuroImage (in press)
  2. Lewis JP, Stephens SH, Horenstein RBO'Connell JR, , Ryan K, Peer CJ, Figg WD, Spencer SD, Pacanowski MA, Mitchell BD, Shuldiner AR.  The CYP2C19*17 variant is not independently associated with clopidogrel response.  J Thromb Haemost (in press)
  3. Mitchell BD, Chandrasekaran S.  Genetics of Type 2 Diabetes.  In: Clinical Genomics: Practical Applications in Adult Patient Care.  M. Murray, M. Babyatsky, M. Giovanni, Eds.  McGraw Hill.  (in press)
  4. Mitchell BD, Schäffer AA, Pollin TI, Streeten EA, Horenstein RB, Steinle NI, Yerges-Armstrong LM, Shuldiner AR, O’Connell JR.  Mapping genes in isolated populations:  lessons from the Old Order Amish.  Chapter X, in Genome Mapping and Genomics in Human and Non-Human Primates.  R Duggirala, AG Comuzzie, S Williams-Blangero, S Paul, Chitta Kole, Eds.  Springer.  (in press)
  5. Parsa A, Fuchsberger C, Kottgen A, O’Seaghdha CM, Pattaro C, et al.  Common variants in Mendelian kidney disease genes and their association with renal function and CKD.  J Am Soc Nephrol (in press)