UM SOM: Global Ethics Education

Henry J. Silverman, MD, MA

Professor of Medicine - University of Maryland School of Medicine

Medical Degree: Johns Hopkins University, 1978

Master’s Degree (Philosophy): Georgetown University, 1995

Biography:

Dr. Silverman is Professor of Medicine at the University of Maryland School of Medicine. He is a faculty member of the Pulmonary & Critical Care Division in the Department of Medicine. In addition to his clinical career, Dr. Silverman has forged a career in the field of medical ethics and research ethics. He is chairperson of the Clinical Ethics Committee at the University of Maryland Medical System.

Dr. Silverman has been a principal investigator on more than 30 critical care trials during the last 20 years. He was the Principal Investigator on the NIH-funded Clinical Trials Network for the Treatment of Acute Respiratory Distress Syndrome. His research ethics activities have included Program Director of the Health Research Ethics Training Initiative In Egypt (HRETIE), member of Institutional Review Boards, member of Data Safety Monitoring Boards, and site surveyor for Accreditation Human Research Protection Programs

Research Ethics Activities

Educational Activities

Principal Investigator: Research Ethics Training Initiative in Egypt (HRETIE)

Research Ethics Committees

Member: Chesapeake Research Review, Inc.

Chair: Research Ethics Committee; NIH-sponsored ARDS Network Clinical Trials Groups

Member: Maryland Medical Research Institute

Data Safety Monitoring Board (DSMB)

Chair: NIH Center for Alternative Medicine Research of Arthritis at the University of Maryland School of Medicine

Member: Double-Blind Placebo Controlled, Randomized Multi-center Study of the Safety and Efficacy of TNF MAb in Patients With Septic Shock

Site Surveyor for Human Research Protection Accreditation Programs

AAHRPP: Association for the Accreditation of Human Research Protection Programs

NCQA Human Research Protection Program for the Veteran Affairs System

Published Articles:

Silverman HJ. Ethical considerations of ensuring an informed and autonomous consent in research involving critically ill patients. Amer J of Respir and Crit Care Med 1996; 154:582-86.

Silverman HJ, Hull S, Sugarman J. Degree of variability among institutional review boards on approved research practices and informed consent in the context of a multi-center clinical trial. Critical Care Medicine. 2001; 29:235-241.

Silverman HJ, Luce JM, Schwartz J.Protecting Decisionally Impaired Subjects In Research: The Need For A Multifaceted Approach. Am J Resp Crit Care Med. 2004; 169:10-14.

Miller FG, Silverman HJ. The Ethical Relevance of the Standard of Care in the Design of Clinical Trials. Am J Resp Crit Care Med. 2004; 169:562-564.

Silverman HJ, Miller FG. Control Group Selection in Critical Care Randomized Controlled Trials Evaluating Interventional Strategies: An Ethical Assessment. Crit Care Med. 2004; 32:852-857.

Silverman HJ, Druml C, Lemaire F, Nelson R. The European Union Directive and the protection of incapacitated subjects in research: an ethical analysis. Intensive Care Medicine. 2004; 9:1723-1729.

Silverman HJ, Luce JM, Lanken PN, Morris AH, Harabin AL, Oldmixon CF, Thompson BT, Bernard GR, for the NHLBI Acute Respiratory Distress Syndrome Clinical Trials Network. Recommendations for informed consent forms for critical care clinical trials. Critical Care Medicine. Crit Care med. 2005; 33:867- 82.

Silverman HJ. Enhancing research ethics capacity: implications for protection of research subjects, avoiding exploitation and achieving global health. Middle East Fertility Society Journal. 2005; 10:105-109.