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Most-Recent Publications


Stoica BA, FADEN AI. Cell death mechanisms and modulation in traumatic brain injury. Neurotherapeutics. 7(1):3-12, 2010.

Pajoohesh-Ganji A, Byrnes KR, Fatemi G, FADEN AI. A combined scoring method to assess behavioral recovery after mouse spinal cord injury. Neurosci Res. 67(2):117-25, 2010.

Kabadi SV, Hilton GD, Stoica BA, Zapple DN, FADEN AI. Fluid percussion-induced traumatic brain injury in rats. Nat. Protocols. 5(9):1552-63. 320, 2010.

Byrnes KR, Fricke ST, FADEN AI. Neurpathological differences between rats and mice after spinal cord injury. J Magn Reson Imaging 32(4):836-46, 2010.

Loane DJ, FADEN AI.  Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies.  Trends Pharmacol Sci. 31(12):596-604, 2010.

Cernak I, Chang T, Ahmed FA, Cruz MI, Vink R, Stoica BA, FADEN AI. Pathophysiological responses to experimental diffuse brain trauma differs as a function of developmental age. Dev. Neurosci. 32(5-6):442-53, 2010

Loane DJ, FADEN AI. Neuroprotection and traumatic brain injury: translational challenges and emerging therapeutic strategies. Trends in Pharmacologicl Sciences. 31(12): 596-604, 2010.

Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, FADEN AI, Burns MP. Modulation of ABCA1 by an LXR antagonist reduces beta-amyloid levels and improves outcome after traumatic brain injury. J Neurotrauma 28(2): 225-236, 2011.

Wu J, Stoica BA, FADEN AI.  Cell Cycle Activation and Spinal Cord Injury. Neurotherapeutics 8(2):221-8, 2011.

FADEN AI. Microglial activation and traumatic brain injury. (Editorial) Annals of Neurology, 70: 345–346, 2011.

Byrnes KR, Washington PM, Knoblach SM, Hoffman E, FADEN AI.  Delayed inflammatory mRNA and protein expression after spinal cord injury. Journal of Neuroinflammation.  2011 Oct; 8:130.

Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, FADEN AI, Burns MP.  Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury.  J Neurotrauma. 2011 Feb; 28(2):225-36.

Kabadi SV, Stoica BA, Hanscom M, Loane DJ, Kharebava G, Murray Ii MG, Cabatbat RM, FADEN AI.  CR8, a Selective and Potent CDK Inhibitor, Provides Neuroprotection in Experimental Traumatic Brain Injury. Neurotherapeutics. 2011 Dec 14. [Epub ahead of print]

Kabadi SV, Stoica BA, Byrnes, KR, Hanscom M, Loane DJ, FADEN AI. Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma. Journal of Cerebral Blood Flow and Metabolism, 32(1):137-49, 2012.

Kabadi SV, Stoica BA, Loane DJ, Byrnes KR, Hanscom M, Cabatbat RM, Tan MT, FADEN AI. Cyclin D1 gene ablation confers neuroprotection in traumatic brain injury. J Neurotrauma. 29(5):813-27, 2012.

Byrnes KR, Loane DJ, Stoica BA, Zhang J, FADEN AI.  Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injuryJ Neuroinflammation. 9:43- , 2012.

Loane DJ, Stoica BA, FADEN AI. Metabotropic glutamate receptor-mediated signaling in neuroglia.  WIREs Membrane Transport and Signaling WIREs  1:136–150, 2012.

Piao CS, Loane DJ, Stoica BA, Li S, Hanscom M, Cabatbat R, Blomgren K, FADEN AI. Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injuryNeurobiol Dis. 2012 Mar 9. [Epub ahead of print]

Wu J, Stoica BA, Dinizo M, Pajoohesh-Ganji A, Piao C, FADEN AI. Delayed cell cycle pathway modulation facilitates recovery after spinal cord injury. Cell Cycle.  May 1,11(9) [Epub ahead of print].

Wu J, Pajoohesh-Ganji A, Stoica BA, Dinizo M, Guanciale K, FADEN AI. Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion. J Neuroinflammation. 2012 Jul 12.

Pajoohesh-Ganji A, Knoblach SM, FADEN AI, Byrnes KR. Characterization of inflammatory gene expression and galectin-3 function after spinal cord injury in mice. Brain Res. 2012 Aug 4. [Epub ahead of print]

Wu J, Kharebava G, Piao C, Stoica BA, Dinizo M, Sabirzhanov B, Hanscom M, Guanciale K, FADEN AI. Inhibition of E2F1/CDK1 pathwayattenuates neuronal apoptosis in vitro and confers neuroprotection after spinal cord injury in vivo. PLoS One. 2012;7(7):e42129. Epub 2012 Jul 25.

Sabirzhanov B, Stoica BA, Hanscom M, Piao CS, FADEN AI. Overexpression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis. J Neurochem. 2012 Aug 21. [Epub ahead of print].

Loane DJ, Stoica BA, Byrnes K, Jeong W, FADEN AI. Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury. J Neurotrauma. 2012 Nov 30. [Epub ahead of print]

Zhao Z, Loane DJ, Murray MG 2nd, Stoica BA, FADEN AI. Comparing the predictive value of multiple cognitive, affective, and motor tasks after rodent traumatic brain injury. J Neurotrauma. 2012 Oct 10;29(15):2475-89. doi: 10.1089/neu.2012.2511. Epub 2012 Aug 27.

Kumar A, Stoica BA, Sabirzhanov B, Burns MP, FADEN AI, Loane DJ.  Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states.  Neurobiol Aging. 2012 Dec 27. doi:pii: S0197-4580(12)00590-8. 10.1016/j.neurobiolaging.2012.11.013. [Epub ahead of print]

Piao CS, Stoica BA, Wu J, Sabirzhanov B, Zhao Z, Cabatbat R, Loane DJ, FADEN AI.  Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injuryNeurobiol Dis. 2013 Jan 8. pii: S0969-9961(13)00008-9. doi: 10.1016/j.nbd.2012.12.017. [Epub ahead of print]