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Patrick F. McArdle
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Patrick F. McArdle Ph.D.

Academic Title: Associate Professor
Primary Appointment: Medicine
Secondary Appointments: Epidemiology & Public Health
Additional Title(s): Associate Director of Reserach Maryland Center of Excellence on Problem Gambling
Location: MSTF 300E
Phone: (410) 706-4180
Fax: (410) 706-1622

Personal History:

I received my undergraduate degree in mechanical and aerospace engineering from Cornell University in 1994. After working in information technology industry I resumed my formal education at the University of Maryland. I completed my doctoral work in epidemiology focusing on genetic epidemiology and aging.

Research Interests:

My primary academic research interests are in new inferential methods applied to go beyond correlation to causation. My approach to causal inference is at the crossroads of statistics, epidemiology and practical application.

Through my affiliation with the Program in Personalized and Genomic Medicine, I work together with a team to advance so-called personalized medicine into the real clinics to direct effect patient outcomes.

As the Associate Director of Research for the Maryland Center on Problem Gambling, I work towards the single goal of the Center: to minimize the problems associate with gambling. I oversee research in this area and take a direct leadership role in maintaining research resources across the State.


Search My Publications in Pub Med

Highlighted Publications

McArdle PF, Pollin TI, O'Connell JR, Sorkin JD, Agarwala R, Schaeffer AA, Streeten EA, King TM, Shuldiner AR, Mitchell BD. Does having children extend lifespan? A genealogical study of parity and longevity in the Amish. J Gerontol A Biol Sci Med Sci. 2006 Feb;61(2):190-5. PMID: 16510865

Song Q, Cole JW, O'Connell JR, Stine OC, Gallagher M, Giles WH, Mitchell BD, Wozniak MA, Stern BJ, Sorkin JD, McArdle PF, Naj AC, Xu Q, Gibbons GH, Kittner SJ. Phosphodiesterase 4d Polymorphisms And The Risk Of Cerebral Infarction In A Biracial Population: The Stroke Prevention In Young Women Study. Hum Mol Genet. 2006 Aug 15;15(16):2468-78. Epub 2006 Jul 11. PMID: 16835261

McArdle PF, O'Connell JR, Pollin TI, Baumgarten M, Shuldiner AR, Peyser PA, Mitchell BD. Accounting for relatedness in family-based genetic association studies. Hum Hered 2007;64:234-242. PMID: 16510865

Rampersaud E, Damcott CM, Fu M, Shen H, McArdle PF, Shi X, Shelton J, Yin J, Chang CY, Ott SH, Zhang L, Zhao Y, Mitchell BD, O'Connell J, Shuldiner AR. Identification of novel candidate genes for type-2 diabetes from a genome-wide association scan in the Old Order Amish: Evidence for replication from diabetes-related quantitative traits and from independent populations. Diabetes. Publish Ahead of Print September 10, 2007 DOI: 10.2337/db07-0457

McArdle PF, Dytch H, O'Connell JR, Shuldiner AR, Peyser PA, Mitchell BD, Abney M. Homozygosity by descent mapping of blood pressure in the Old Order Amish: evidence for sex specific genetic architecture. BMC Genetics 2007, 8:66 (1 October 2007).