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Nader N. Hanna

Nader N. Hanna M.B.,B.Ch.

Academic Title: Professor
Primary Appointment: Surgery
Additional Title(s): 1. Director of Clinical Operations, Division of General & Oncologic Surgery; 2. Cancer Institute Director, University of Maryland, St. Joseph Medical Center
Location: 29 S. Greene Street, Suite 600
Phone: 410-328-7320
Fax: 410-328-5919
Cell: 410-460-0115

Personal History:

Dr. Hanna is a Professor of Surgery at the University of Maryland School of Medicine. He completed an accredited Surgical Oncology fellowship at the University of Chicago, Pritzker School of Medicine. He is the recipient of several achievement and educational awards and is repeatedly listed as Top doc, Baltimore magazine, and US world news and Reports. His expertise include advanced and complex surgical oncology procedures for advanced/recurrent and metastatic gastrointestinal cancers, including esophagectomy, gastrectomy, major liver resection, Whipple procedure, pelvic exenteration and cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. His research interests include gene therapy for pancreatic cancer, radio-sensitization for GI malignancies, outcomes research and clinical trials. He is a national/international speaker in gastrointestinal cancers. He is well published in various high impact journals including Nature, Nature Medicine, Cancer Research, Human Gene therapy, Journal of Clinical Oncology, Oncologist, Colorectal disease, Annals of Surgical Oncology, Annals of Surgery and Journal of American college of Surgeons.

Research Interests:

Dr. Hanna's research interest include gene therapy for pancreatic cancer and radio-sensitization for GI malignancies outcomes research clinical trials.

Clinical Specialty:

  1. Gatrointestinal cancers: pancreatic, liver, bile ducts, gastric, esophageal, appendix, colorectal, small bowel, and gastrointestinal stromal tumors
  2. Retroperitoneal and extremity soft tissue sarcoma
  3. Peritoneal surface malignancies (carcinomatosis): from appendix, colorectal, gastric, ovarian, endometrial cancers and mesothelioma
  4. Conservative organ-sparing surgery, including State of the art Robotic and Laparoscopic minimally invasive cancer surgery for colorectal, pancreatic, gastric, liver, splenic and adrenal tumors and sphincter-preservation surgery for rectal cancer.


Hallahan DE, Mauceri HJ, Seung LP, Dunphy EJ, Wayne JD, Hanna N, Toledano A, Hellman S, Kufe DW, Weichselbaum RR. Spatial and temporal control of gene therapy using ionizing radiation. Nat Med. 1995 Aug;1(8):786-91. PubMed PMID: 7585181.

Hanna N, O'Donnell K, Wolfe GR. Alveolar soft part sarcoma metastatic to the breast. J Surg Oncol. 1996 Feb;61(2):159-62. PubMed PMID: 8606550.

Mauceri HJ, Hanna N, Wayne JD, Hallahan DE, Hellman S, Weichselbaum RR. Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature. Cancer Res. 1996 Oct 1;56(19):4311-4. PubMed PMID: 8813113.

Hanna N, Hallahan DE, Wayne JD, Weischselbaum RR. Modification of the Radiation Response by the Administration of Exogenous Genes. Semin Radiat Oncol. 1996 Oct;6(4):321-328. PubMed PMID: 10717189.

Hanna N, Mauceri HJ, Wayne JD, Hallahan DE, Kufe DW, Weichselbaum RR. Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts. Cancer Res. 1997 Oct 1;57(19):4205-9. PubMed PMID: 9331076.

Mauceri HJ, Hanna N, Beckett MA, Gorski DH, Staba MJ, Stellato KA, Bigelow K, Heimann R, Gately S, Dhanabal M, Soff GA, Sukhatme VP, Kufe DW, Weichselbaum RR. Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature. 1998 Jul 16;394(6690):287-91. PubMed PMID: 9685160.

Hanna N, McGrath PC, Sloan DA, Kenady DE. Advances in the pathogenesis and treatment of thyroid cancer. Curr Opin Oncol. 1999 Jan;11(1):42-7. Review. PubMed PMID: 9914877.

Mauceri HJ, Hanna N, Staba MJ, Beckett MA, Kufe DW, Weichselbaum RR. Radiation-inducible gene therapy. C R Acad Sci III. 1999 Feb-Mar;322(2-3):225-8. Review. PubMed PMID: 10196676.

Hanna N, Kenady DE. Hypertension in patients with pheochromocytoma. Curr Hypertens Rep. 1999 Dec;1(6):540-5. PubMed PMID: 10981118.

Hanna N, Kenady DE. Advances in the management of adrenal tumors. Curr Opin Oncol. 2000 Jan;12(1):49-53. Review. PubMed PMID: 10687729.

Hanna N, Seetharam S, Mauceri HJ, Beckett MA, Jaskowiak NT, Salloum RM, Hari D, Dhanabal M, Ramchandran R, Kalluri R, Sukhatme VP, Kufe DW, Weichselbaum RR. Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J. 2000 Sep-Oct;6(5):287-93. PubMed PMID: 11079167.

Mohiuddin M, Hayne M, Regine WF, Hanna N, Hagihara PF, McGrath P, Marks GM. Prognostic significance of postchemoradiation stage following preoperative chemotherapy and radiation for advanced/recurrent rectal cancers. Int J Radiat Oncol Biol Phys. 2000 Nov 1;48(4):1075-80. PubMed PMID: 11072165.

Sharma A, Mani S, Hanna N, Guha C, Vikram B, Weichselbaum RR, Sparano J, Sood B, Lee D, Regine W, Muhodin M, Valentino J, Herman J, Desimone P, Arnold S, Carrico J, Rockich AK, Warner-Carpenter J, Barton-Baxter M. Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors. Hum Gene Ther. 2001 Jun 10;12(9):1109-31. PubMed PMID: 11399232.

Mohiuddin M, Kudrimoti M, Regine WF, McGrath PC, Hanna N, John W. Concurrent infusional gemcitabine and radiation in the treatment of advanced unresectable GI malignancy: a phase I study. Cancer J. 2002 May-Jun;8(3):255-62. PubMed PMID: 12074325.

Hanna N, Guillem J, Dosoretz A, Steckelman E, Minsky BD, Cohen AM. Intraoperative parasympathetic nerve stimulation with tumescence monitoring during total mesorectal excision for rectal cancer. J Am Coll Surg. 2002 Oct;195(4):506-12. PubMed PMID: 12375756.

Salloum RM, Saunders MP, Mauceri HJ, Hanna N, Gorski DH, Posner MC, Stratford IJ, Weichselbaum RR. Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay. Am Surg. 2003 Jan;69(1):24-7. Erratum in: Am Surg. 2003 Apr;69(4):362. PubMed PMID: 12575775.

Hanna N, Mentzer RM Jr. Molecular genetics and management strategies in hereditary cancer syndromes. J Ky Med Assoc. 2003 Mar;101(3):100-7. Review. PubMed PMID: 12674901.

Hanna N, Cohen AM. Ovarian neoplasms in patients with colorectal cancer: understanding the role of prophylactic oophorectomy. Clin Colorectal Cancer. 2004 Feb;3(4):215-22. Review. PubMed PMID: 15025793.

Senzer N, Mani S, Rosemurgy A, Nemunaitis J, Cunningham C, Guha C, Bayol N, Gillen M, Chu K, Rasmussen C, Rasmussen H, Kufe D, Weichselbaum R, Hanna N. TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors. J Clin Oncol. 2004 Feb 15;22(4):592-601. Epub 2004 Jan 15. PubMed PMID: 14726502.

Hanna N. Radiofrequency ablation of primary and metastatic hepatic malignancies. Clin Colorectal Cancer. 2004 Jul;4(2):92-100. Review. PubMed PMID: 15285816.

Mundt AJ, Vijayakumar S, Nemunaitis J, Sandler A, Schwartz H, Hanna N, Peabody T, Senzer N, Chu K, Rasmussen CS, Kessler PD, Rasmussen HS, Warso M, Kufe DW, Gupta TD, Weichselbaum RR. A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities. Clin Cancer Res. 2004 Sep 1;10(17):5747-53. PubMed PMID: 15355902.

Gaugler JE, Hanna N, Linder J, Given CW, Tolbert V, Kataria R, Regine WF. Cancer caregiving and subjective stress: a multi-site, multi-dimensional analysis. Psychooncology. 2005 Sep;14(9):771-85. PubMed PMID: 15750995.

Saidi RF, ReMine SG, Dudrick PS, Hanna N. Is there a role for palliative gastrectomy in patients with stage IV gastric cancer? World J Surg. 2006 Jan;30(1):21-7. PubMed PMID: 16369718.

Mohiuddin M, Winter K, Mitchell E, Hanna N, Yuen A, Nichols C, Shane R, Hayostek C, Willett C; Radiation Therapy Oncology Group Trial 0012. Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology Group Trial 0012. J Clin Oncol. 2006 Feb 1;24(4):650-5. PubMed PMID: 16446336.

Alexander HR, Hanna N, Pingpank JF. Clinical results of cytoreduction and HIPEC for malignant peritoneal mesothelioma. Cancer Treat Res. 2007;134:343-55. Review. PubMed PMID: 17633065.

Esquivel J, Sticca R, Sugarbaker P, Levine E, Yan TD, Alexander R, Baratti D, Bartlett D, Barone R, Barrios P, Bieligk S, Bretcha-Boix P, Chang CK, Chu F, Chu Q, Daniel S, de Bree E, Deraco M, Dominguez-Parra L, Elias D, Flynn R, Foster J, Garofalo A, Gilly FN, Glehen O, Gomez-Portilla A, Gonzalez-Bayon L, Gonzalez-Moreno S, Goodman M, Gushchin V, Hanna N, Hartmann J, Harrison L, Hoefer R, Kane J, Kecmanovic D, Kelley S, Kuhn J, Lamont J, Lange J, Li B, Loggie B, Mahteme H, Mann G, Martin R, Misih RA, Moran B, Morris D, Onate-Ocana L, Petrelli N, Philippe G, Pingpank J, Pitroff A, Piso P, Quinones M, Riley L, Rutstein L, Saha S, Alrawi S, Sardi A, Schneebaum S, Shen P, Shibata D, Spellman J, Stojadinovic A, Stewart J, Torres-Melero J, Tuttle T, Verwaal V, Villar J, Wilkinson N, Younan R, Zeh H, Zoetmulder F, Sebbag G; Society of Surgical Oncology Annual Meeting. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: a consensus statement. Society of Surgical Oncology. Ann Surg Oncol. 2007 Jan;14(1):128- Epub 2006 Oct 28. Erratum in: Ann Surg Oncol. 2011 Dec;18 Suppl 3:S334-5. PubMed PMID: 17072675.

Regine WF, Hanna N, Garofalo MC, Doyle A, Arnold S, Kataria R, Sims J, Tan M, Mohiuddin M. Low-dose radiotherapy as a chemopotentiator of gemcitabine in tumors of the pancreas or small bowel: a phase I study exploring a new treatment paradigm. Int J Radiat Oncol Biol Phys. 2007 May 1;68(1):172-7. Epub 2007 Feb 2. PubMed PMID: 17276612.

Nugent SL, Cunningham SC, Alexiev BA, Bellavance E, Papadimitriou JC, Hanna N. Composite signet-ring cell/neuroendocrine carcinoma of the stomach with a metastatic neuroendocrine carcinoma component: a better prognosis entity. Diagn Pathol. 2007 Nov 7;2:43. PubMed PMID: 17988399; PubMed Central PMCID: PMC2174438.

Young PE, Oosterveen S, Hanna N, Darwin PE. Presacral schwannoma diagnosed by EUS-guided FNA. Gastrointest Endosc. 2008 Feb;67(2):383-5. Epub 2007 Nov 5. PubMed PMID: 17981275.

Davidoff AJ, Rapp T, Onukwugha E, Zuckerman IH, Hanna N, Pandya N, Mullins CD. Trends in disparities in receipt of adjuvant therapy for elderly stage III colon cancer patients: the role of the medical oncologist evaluation. Med Care. 2009 Dec;47(12):1229-36. doi: 10.1097/MLR.0b013e3181b58a85. PubMed PMID: 19786906.

Turner PL, Ilano AG, Zhu Y, Johnson SB, Hanna N. ACS-NSQIP criteria are associated with APACHE severity and outcomes in critically ill surgical patients. J Am Coll Surg. 2011 Mar;212(3):287-94. doi: 10.1016/j.jamcollsurg.2010.12.011. PubMed PMID: 21356486.

Hanna N, Bellavance E, Keay T. Palliative surgical oncology. Surg Clin North Am. 2011 Apr;91(2):343-53, viii. doi: 10.1016/j.suc.2010.12.004. PubMed PMID: 21419257.

Yovino S, Poppe M, Jabbour S, David V, Garofalo M, Pandya N, Alexander R, Hanna N, Regine WF. Intensity-modulated radiation therapy significantly improves acute gastrointestinal toxicity in pancreatic and ampullary cancers. Int J Radiat Oncol Biol Phys. 2011 Jan 1;79(1):158-62. doi: 10.1016/j.ijrobp.2009.10.043. Epub 2010 Apr 14. PubMed PMID: 20399035.

Costello LC, Levy BA, Desouki MM, Zou J, Bagasra O, Johnson LA, Hanna N, Franklin RB. Decreased zinc and downregulation of ZIP3 zinc uptake transporter in the development of pancreatic adenocarcinoma. Cancer Biol Ther. 2011 Aug 15;12(4):297-303. Epub 2011 Aug 15. PubMed PMID: 21613827; PubMed Central PMCID: PMC3173731.

Hsiao FY, Mullins CD, Onukwugha E, Pandya N, Hanna N. Comparative effectiveness of different chemotherapeutic regimens on survival of people aged 66 and older with stage III colon cancer: a "real world" analysis using Surveillance, Epidemiology, and End Results-Medicare data. J Am Geriatr Soc. 2011 Sep;59(9):1717-23. doi: 10.1111/j.1532-5415.2011.03501.x. Epub 2011 Aug 10. PubMed PMID: 21831168.

Hanna N, Bikov KA, McNally D, Onwudiwe NC, Dalal M, Mullins CD. Impact of venous thromboembolism on mortality of elderly Medicare patients with stage III colon cancer. Oncologist. 2012;17(9):1191-7. Epub 2012 Jul 5. PubMed PMID: 22767876; PubMed Central PMCID: PMC3448412.

Zhang G, Schetter A, He P, Funamizu N, Gaedcke J, Ghadimi BM, Ried T, Hassan R, Yfantis HG, Lee DH, Lacy C, Maitra A, Hanna N, Alexander HR, Hussain SP. DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma. PLoS One. 2012;7(2):e31507. doi: 10.1371/journal.pone.0031507. Epub 2012 Feb 20. PubMed PMID: 22363658; PubMed Central PMCID: PMC3282755.

Hanna N, Onukwugha E, Choti MA, Davidoff AJ, Zuckerman IH, Hsu VD, Mullins CD. Comparative analysis of various prognostic nodal factors, adjuvant chemotherapy and survival among stage III colon cancer patients over 65 years: an analysis using surveillance, epidemiology and end results (SEER)-Medicare data. Colorectal Dis. 2012 Jan;14(1):48-55. doi: 10.1111/j.1463-1318.2011.02545.x. PubMed PMID: 21689262.

Janne d'Othe B, Sofocleous CT, Hanna N, Lewandowski RJ, Soulen MC, Vauthey JN, Cohen SJ, Venook AP, Johnson MS, Kennedy AS, Murthy R, Geschwind JF, Kee ST. Development of a research agenda for the management of metastatic colorectal cancer: proceedings from a multidisciplinary research consensus panel. J Vasc Interv Radiol. 2012 Feb;23(2):153-63. doi: 10.1016/j.jvir.2011.12.003. PubMed PMID: 22264550; PubMed Central PMCID: PMC4352314.

Hecht JR, Farrell JJ, Senzer N, Nemunaitis J, Rosemurgy A, Chung T, Hanna N, Chang KJ, Javle M, Posner M, Waxman I, Reid A, Erickson R, Canto M, Chak A, Blatner G, Kovacevic M, Thornton M. EUS or percutaneously guided intratumoral TNFerade biologic with 5-fluorouracil and radiotherapy for first-line treatment of locally advanced pancreatic cancer: a phase I/II study. Gastrointest Endosc. 2012 Feb;75(2):332-8. doi: 10.1016/j.gie.2011.10.007. PubMed PMID: 22248601; PubMed Central PMCID: PMC4380192.

Chang KJ, Reid T, Senzer N, Swisher S, Pinto H, Hanna N, Chak A, Soetikno R. Phase I evaluation of TNFerade biologic plus chemoradiotherapy before esophagectomy for locally advanced resectable esophageal cancer. Gastrointest Endosc. 2012 Jun;75(6):1139-46.e2. doi: 10.1016/j.gie.2012.01.042. Epub 2012 Apr 18. PubMed PMID: 22520270; PubMed Central PMCID: PMC4543382.

Franklin RB, Levy BA, Zou J, Hanna N, Desouki MM, Bagasra O, Johnson LA, Costello LC. ZIP14 zinc transporter downregulation and zinc depletion in the development and progression of hepatocellular cancer. J Gastrointest Cancer. 2012 Jun;43(2):249-57. doi: 10.1007/s12029-011-9269-x. PubMed PMID: 21373779; PubMed Central PMCID: PMC3724761.

Hanna N, Ohana P, Konikoff FM, Leichtmann G, Hubert A, Appelbaum L, Kopelman Y, Czerniak A, Hochberg A. Phase 1/2a, dose-escalation, safety, pharmacokinetic and preliminary efficacy study of intratumoral administration of BC-819 in patients with unresectable pancreatic cancer. Cancer Gene Ther. 2012 Jun;19(6):374-81. doi: 10.1038/cgt.2012.10. Epub 2012 Apr 13. PubMed PMID: 22498722.

Mullins CD, Hsiao FY, Onukwugha E, Pandya NB, Hanna N. Comparative and cost-effectiveness of oxaliplatin-based or irinotecan-based regimens compared with 5-fluorouracil/leucovorin alone among US elderly stage IV colon cancer patients. Cancer. 2012 Jun 15;118(12):3173-81. doi: 10.1002/cncr.26613. Epub 2011 Oct 21. PubMed PMID: 22020739.

Yovino S, Maidment BW 3rd, Herman JM, Pandya N, Goloubeva O, Wolfgang C, Schulick R, Laheru D, Hanna N, Alexander R, Regine WF. Analysis of local control in patients receiving IMRT for resected pancreatic cancers. Int J Radiat Oncol Biol Phys. 2012 Jul 1;83(3):916-20. doi: 10.1016/j.ijrobp.2011.08.026. Epub 2012 Jan 25. PubMed PMID: 22284684; PubMed Central PMCID: PMC3556989.

Mahmood U, Errens M, Zimrin A, Hanna N, Amin P, Sharma N. The remarkably distensible stomach: Case report highlighting the implications of gastric filling on radiation treatment planning for gastric lymphoma. Pract Radiat Oncol. 2012 Oct-Dec;2(4):265-9. doi: 10.1016/j.prro.2011.08.006. Epub 2011 Oct 1. PubMed PMID: 24674162.

Funamizu N, Hu C, Lacy C, Schetter A, Zhang G, He P, Gaedcke J, Ghadimi MB, Ried T, Yfantis HG, Lee DH, Subleski J, Chan T, Weiss JM, Back TC, Yanaga K, Hanna N, Alexander HR, Maitra A, Hussain SP. Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. Int J Cancer. 2013 Feb;132(4):785-94. doi: 10.1002/ijc.27736. PubMed PMID: 22821831; PubMed Central PMCID: PMC3488363.

Zhu Y, Hanna N, Boutros C, Alexander HR Jr. Assessment of clinical benefit and quality of life in patients undergoing cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for management of peritoneal metastases. J Gastrointest Oncol. 2013 Mar;4(1):62-71. doi: 10.3978/j.issn.2078-6891.2012.053. PubMed PMID: 23450068; PubMed Central PMCID: PMC3562622.

Turner KM, Hanna N, Zhu Y, Jain A, Kesmodel SB, Switzer RA, Taylor LM, Richard Alexander H Jr. Assessment of neoadjuvant chemotherapy on operative parameters and outcome in patients with peritoneal dissemination from high-grade appendiceal cancer. Ann Surg Oncol. 2013 Apr;20(4):1068-73. doi: 10.1245/s10434-012-2789-1. Epub 2013 Mar 2. PubMed PMID: 23456383.

Lissauer ME, Diaz JJ, Narayan M, Shah PK, Hanna N. Surgical intensive care unit admission variables predict subsequent readmission. Am Surg. 2013 Jun;79(6):583-8. PubMed PMID: 23711267.

Alexander HR Jr, Bartlett DL, Pingpank JF, Libutti SK, Royal R, Hughes MS, Holtzman M, Hanna N, Turner K, Beresneva T, Zhu Y. Treatment factors associated with long-term survival after cytoreductive surgery and regional chemotherapy for patients with malignant peritoneal mesothelioma. Surgery. 2013 Jun;153(6):779-86. doi: 10.1016/j.surg.2013.01.001. Epub 2013 Mar 13. PubMed PMID: 23489943; PubMed Central PMCID: PMC3734959.

Breunig IM, Shaya FT, Hanna N, Seal B, Chirikov VV, Daniel Mullins C. Transarterial chemoembolization treatment: association between multiple treatments, cumulative expenditures, and survival. Value Health. 2013 Jul-Aug;16(5):760-8. doi: 10.1016/j.jval.2013.03.1630. Epub 2013 May 28. PubMed PMID: 23947969.

Mohiuddin M, Paulus R, Mitchell E, Hanna N, Yuen A, Nichols R, Yalavarthi S, Hayostek C, Willett C. Neoadjuvant chemoradiation for distal rectal cancer: 5-year updated results of a randomized phase 2 study of neoadjuvant combined modality chemoradiation for distal rectal cancer. Int J Radiat Oncol Biol Phys. 2013 Jul 1;86(3):523-8. doi: 10.1016/j.ijrobp.2013.02.020. Epub 2013 Mar 29. PubMed PMID: 23545284; PubMed Central PMCID: PMC4201041.

Zhang G, He P, Gaedcke J, Ghadimi BM, Ried T, Yfantis HG, Lee DH, Hanna N, Alexander HR, Hussain SP. FOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer. Cancer Res. 2013 Sep 1;73(17):5416-25. doi: 10.1158/0008-5472.CAN-13-0362. Epub 2013 Jun 25. PubMed PMID: 23801748; PubMed Central PMCID: PMC3766408.

Zhang G, He P, Tan H, Budhu A, Gaedcke J, Ghadimi BM, Ried T, Yfantis HG, Lee DH, Maitra A, Hanna N, Alexander HR, Hussain SP. Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer. Clin Cancer Res. 2013 Sep 15;19(18):4983-93. doi: 10.1158/1078-0432.CCR-13-0209. Epub 2013 Aug 5. PubMed PMID: 23918603; PubMed Central PMCID: PMC3778077.

Chirikov VV, Mullins CD, Hanna N, Breunig IM, Seal B, Shaya FT. Multispecialist Care and Mortality in Hepatocellular Carcinoma. Am J Clin Oncol. 2013 Sep 21. [Epub ahead of print] PubMed PMID: 24064759.

Jain A, Poonia B, So EC, Vyzasatya R, Burch EE, Olsen HS, Mérigeon EY, Block DS, Zhang X, Schulze DH, Hanna N, Twadell WS, Yfantis HG, Chan SL, Cai L, Strome SE. Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer. Eur J Cancer. 2013 Oct;49(15):3344-52. doi: 10.1016/j.ejca.2013.06.009. Epub 2013 Jul 18. PubMed PMID: 23871153.

Reese ES, Onukwugha E, Hanna N, Seal BS, Mullins CD. Clinical and demographic characteristics associated with the receipt of chemotherapy treatment among 7951 elderly metastatic colon cancer patients. Cancer Med. 2013 Dec;2(6):907-15. doi: 10.1002/cam4.143. Epub 2013 Oct 10. PubMed PMID: 24403264; PubMed Central PMCID: PMC3892395.

Shaya FT, Breunig IM, Seal B, Mullins CD, Chirikov VV, Hanna N. Comparative and cost effectiveness of treatment modalities for hepatocellular carcinoma in SEER-Medicare. Pharmacoeconomics. 2014 Jan;32(1):63-74. doi: 10.1007/s40273-013-0109-7. PubMed PMID: 24293197.

Zheng Z, Hanna N, Onukwugha E, Reese ES, Seal B, Mullins CD. Does the type of first-line regimens influence the receipt of second-line chemotherapy treatment? An analysis of 3211 metastatic colon cancer patients. Cancer Med. 2014 Feb;3(1):124-33. doi: 10.1002/cam4.176. Epub 2014 Jan 7. PubMed PMID: 24403130; PubMed Central PMCID: PMC3930397.

Zheng Z, Hanna N, Onukwugha E, Bikov KA, Mullins CD. Hospital center effect for laparoscopic colectomy among elderly stage I-III colon cancer patients. Ann Surg. 2014 May;259(5):924-9. doi: 10.1097/SLA.0b013e31829d0468. PubMed PMID: 23817508.

Turaga K, Levine E, Barone R, Sticca R, Petrelli N, Lambert L, Nash G, Morse M, Adbel-Misih R, Alexander HR, Attiyeh F, Bartlett D, Bastidas A, Blazer T, Chu Q, Chung K, Dominguez-Parra L, Espat NJ, Foster J, Fournier K, Garcia R, Goodman M, Hanna N, Harrison L, Hoefer R, Holtzman M, Kane J, Labow D, Li B, Lowy A, Mansfield P, Ong E, Pameijer C, Pingpank J, Quinones M, Royal R, Salti G, Sardi A, Shen P, Skitzki J, Spellman J, Stewart J, Esquivel J. Consensus guidelines from The American Society of Peritoneal Surface Malignancies on standardizing the delivery of hyperthermic intraperitoneal chemotherapy (HIPEC) in colorectal cancer patients in the United States. Ann Surg Oncol. 2014 May;21(5):1501-5. doi: 10.1245/s10434-013-3061-z. Epub 2013 Jun 21. Review. PubMed PMID: 23793364.

Zheng Z, Onukwugha E, Hanna N, Bikov K, Seal B, Mullins CD. Cost-effectiveness of second-line chemotherapy/biologics among elderly metastatic colon cancer patients. Adv Ther. 2014 Jul;31(7):724-34. doi: 10.1007/s12325-014-0134-8. Epub 2014 Jul 15. PubMed PMID: 25022528; PubMed Central PMCID: PMC4115177.

Thom KA, Standiford HC, Johnson JK, Hanna N, Furuno JP. Effectiveness of an antimicrobial polymer to decrease contamination of environmental surfaces in the clinical setting. Infect Control Hosp Epidemiol. 2014 Aug;35(8):1060-2. doi: 10.1086/677159. Epub 2014 Jun 20. PubMed PMID: 25026625; PubMed Central PMCID: PMC4294176.

Steinhardt JJ, Peroutka RJ, Mazan-Mamczarz K, Chen Q, Houng S, Robles C, Barth RN, DuBose J, Bruns B, Tesoriero R, Stein D, Fang R, Hanna N, Pasley J, Rodriguez C, Kligman MD, Bradley M, Rabin J, Shackelford S, Dai B, Landon AL, Scalea T, Livak F, Gartenhaus RB. Inhibiting CARD11 translation during BCR activation by targeting the eIF4A RNA helicase. Blood. 2014 Dec 11;124(25):3758-67. doi: 10.1182/blood-2014-07-589689. Epub 2014 Oct 15. PubMed PMID: 25320244; PubMed Central PMCID: PMC4263984.

Bikov KA, Mullins CD, Seal B, Onukwugha E, Hanna N. Algorithm for Identifying Chemotherapy/Biological Regimens for Metastatic Colon Cancer in SEER-Medicare. Med Care. 2015 Aug; 53(8):e58-64. doi: 10.1097/MLR.0b013e31828fad9f. PubMed. PMID: 23552436

Yang S, He P, Wang J, Schetter A, Tang W, Funamizu N, Yanaga K, Uwagawa T, Satoskar AR, Gaedcke J, Bernhardt M, Ghadimi BM, Gaida MM, Bergmann F, Werner J, Ried T, Hanna N, Alexander HR, Hussain SP. A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2. Cancer Res. 2016 Apr 20. pii: canres.2841.2015. [Epub ahead of print] PMID: 27197190

Bikov KA, Mullins CD, Hung A, Seal B, Onukwugha E, Hanna N. Patterns of Biologics Use Across Treatment Lines in Elderly (Age >65) Medicare Patients With Metastatic Colon Cancer. Oncologist. 2016 Jun;21(6):676-83. doi: 10.1634/theoncologist.2015-0199. Epub 2016 Apr 28. PMID: 27125751

Katz SC, Point GR, Cunetta M, Thorn M, Guha P, Espat NJ, Boutros C, Hanna N, Junghans RP. Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery. Cancer Gene Ther. 2016 May; 23(5):142-8. doi: 10.1038/cgt.2016.14. Epub 2016 Apr 15. PMID: 27080226

Woldemichael A, Onukwugha E, Seal B, Hanna N, Mullins CD. Sequential Therapies and the Cost-Effectiveness of Treating Metastatic Colon Cancer Patients. J Manag Care Spec Pharm. 2016 Jun; 22(6):628-39. doi: 10.18553/jmcp.2016.22.6.628. PMID: 27231791

Asare EA, Compton CC, Hanna N, Kosinski LA, Washington MK, Kakar S, Weiser MR, Overman MJ. The impact of stage, grade, and mucinous histology on the efficacy of systemic chemotherapy in adenocarcinomas of the appendix: Analysis of the National Cancer Data Base. Cancer. 2016 Jan 15;122(2):213-21. doi: 10.1002/cncr.29744. Epub 2015 Oct 27. PMID: 26506400

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