My research interests focus on utilization of echocardiography to characterize cardiac anatomy and function in large population cohorts, including population-based elderly individuals, and in multicenter clinical trials of disease treatment. Additionally, research is being done on relationships between behavior, psychological stress and cardiovascular diseases including coronary heart disease and heart failure. Research is also being carried out on echocardiographic characterization of cardiac dyssynchrony.
Clinical interests are in the application of echocardiography to determine the effects of systemic disease on the heart, the cardiac effects of hypertension, cardiac dyssynchrony and transesophageal echocardiography.
Gottdiener JS, Krantz DS, Howell RH, Hecht GM, Klein J, Falconer JJ, Rozanski A. Induction of silent myocardial ischemia with mental stress testing: Relationship to the triggers of ischemia during daily life activities and to ischemic functional severity. J Am Coll Cardiol 24:1645-1651, 1994
Gottdiener JS, Reda DJ, Massie BM, Materson BJ, Williams DW, Anderson RJ. Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. Circulation, 95:2007-2014, 1997
Gottdiener JS, Reda DJ, Williams DW, Materson BJ, Cushman W, Anderson RJ. Effect of single-drug therapy on reduction of left atrial size in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs cooperative study group on antihypertensive agents. Circulation 98:140-148, 1998
Gottdiener JS, Arnold AA, Aurigemma GP, Polak JF, Tracy RP, Smith VE, Gardin JM, Rutledge JE, Boineau RC. Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study. J Am Coll Cardiol, 35:1628-37, 2000
Gottdiener JS,McClelland R, Marshall RJ, Shemanski L, Furberg CD, Kitzman DW, Cushman M, Polak J, Gardin JM, Gersh BJ, Manolio TA. Outcome of congestive heart failure in the elderly: Influence of left ventricular systolic function. The Cardiovascular Health Study. Ann Int Med, 137(8) 631-639,2002
Gottdiener JS, Bednarz J, Devereux RD, Gardin JM, Klein A, Kitzman D, Manning W, Morehead A, Oh J, Quinones M, Riley W, Schiller N, Stein J, Weissman, N. Americian Society of Echocardiography: Recommendations for use of echocardiography in clinical trials. A report from the American Society of Echocardiography’s nomenclature and standards committee and the task force on echocardiography in clinical trials. J Am Soc Echocardiogr. 17(10):1086-119,2004
Gottdiener JS, Kop WJ, Hausner E, McCeney MK, Herrington D, Krantz, DS: Effects of mental stress on flow mediated brachial arterial dilation and influence of behavioral factors and hypercholesterolemia in subjects without cardiovascular disease. Am J. Cardiol. 15;92(6) 687-91, 2003
Gottdiener, JS. Overview of Stress Echocardiography: Uses, Advantages, and Limitations; Progress In Cardiovascular Disease (ed. M. Lesch); Stress Imaging, eds. Rozanski Gottdiener JS, 2001:43,no.4; 315-334
Gottdiener JS, Diamond JA, Phillips, RA. "Hypertension: impact of echocardiographic data on the mechanism of hypertension, treatment options, prognosis, and assessment of therapy." In CM Otto (Ed.):Clinical Echocardiography,W.B. Saunders, Co., 2nd edition, 2002
Gottdiener JS, Kitzman DF, Aurigemma GP, Arnold AM, Manolio T. Left atrial volume, geometry and function in systolic and diastolic heart failure of the elderly. Predictive value for incident heart failure. Am J Cardiol, 1;97(1):83-9, 2006