1. Development of centeral nervous system-selective estrogen therapy for the treatment of menopausal and andropausal symptoms.
2. Mechanism by which gonadotrophins effect egg aneuplody and fertility.
3. The role of SNPs of serotonin and norepinephrine transporters in the pathomechanism of hot flushes.
4. Neuroprotection by estrogen
Lab Techniques and Equipment:
Immunocytochemistry, in situ hybridization histochemistry, imaging, confocal and laser-dissecting microscopy, stereotaxic surgeries, animal models of hot flush, focal ischemia (stroke), global ischemia (heart attack).
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