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Yi Ning M.D., Ph.D.

Academic Title: Clinical Associate Professor
Primary Appointment: Pathology
yning@som.umaryland.edu
Location: MSTF, 717
Phone: 410-706-4063

Personal History:

Education

  • M.D., Shanghai First Medical College, Shanghai, P.R. China, 1984
  • Ph.D., Baylor College of Medicine, Houston, TX, 1991

Post Graduate Training

  • Fellow, Dept. Human Genetics, Baylor College of Medicine, Houston, TX
  • Fellow, National Human Genome Research Institute, NIH, Bethesda, MD

Publications:

Schrock, E., du Manoir, S., Veldman, T., Schoell, B., Wienberg, J., Ferguson-Smith, M.A., Ning, Y., Ledbetter, D.H., Bar-Am, I., Soenksen, D., Garini, Y., and Ried, T.: Multicolor spectral karyotyping of human chromosomes. Science 273:494-497. 1996.

Ning, Y., Roschke, A., Smith, A.C.M., Macha, M., Precht, K., Riethman, H., Ledbetter, D.H. (group 1), Flint, J., Horsley, S., Regan, R., Kearney, L., Knight, S., Kvaloy, K., Brown, W.R.A. (group 2). A complete set of human telomeric probes and their clinical application. Nature Genetics 14:86-89. 1996.

Ning, Y., Laundon, C.H., Schrock, E., Buchanan, P., and Ried, T.: Prenatal diagnosis of a mosaic extra structurally abnormal chromosome by spectral karyotyping. Prenatal Diagnosis 19:480-482. 1999.

Rosenberg, M.J., Vaske, D., Killoran, C.E., Ning, Y., Wargowski, D., Hudgins, L., Tifft, C.J., Meck, J., Blancato, J.K., Rosenbaum, K., Pauli, R.M., Weber, J., and Biesecker, L.G.: Detection of chromosomal aberrations by a whole-genome microsatellite screen. Am J Hum Genet 66:419-427. 2000.

Knight, S.J., Lese, C.M., Precht, K.S., Kuc, J., Ning, Y., Lucas, S., Regan, R., Brenan, M., Nicod, A., Lawrie, N.M., Cardy, D.L., Nguyen, H., Hudson, T.J., Riethman, H.C., Ledbetter, D.H., and Flint, J.: An optimized set of human telomere clones for studying telomere integrity and architecture. Am J Hum Genet 67:320-332. 2000.

Ning, Y., Xu, J.F., Li, Y., Chavez, L., Riethman, H.C., Lansdorp, P.M., and Weng, N.: Telomere length and the expression of natural telomeric genes in human fibroblasts. Hum Mol Genet 12:1329-1336. 2003.

Thomas, L., Stamberg, J., Gojo, I., Ning, Y., and Rapoport, A.P.: Double minute chromosomes in monoblastic (M5) and myeloblastic (M2) acute myeloid leukemia: two case reports and a review of literature. Am J Hematol 77:55-61. 2004.

Crowley, J.A., Butler, M.S., Ronnenburg, M.J., Ament, C.N., Meekins, J.S., and Ning, Y.: Development of a dual color FISH probe set on chromosome 6q to improve cytogenetic diagnosis of lymphoid malignancies. Cancer Genet Cytogenet 157:78-81. 2005.

Crowley, J.A., Wang, Y., Rapoport, A.P., and Ning, Y.: Detection of MOZ-CBP fusion in acute myeloid leukemia with 8;16 translocation. Leukemia 12:2344-2345. 2005.

Cancer and Leukemia Group B 8461; Farag SS, Archer KJ, Mrozek K, Ruppert AS, Carroll AJ, Vardiman JW, Pettenati MJ, Baer MR, Qumsiyeh MB, Koduru PR, Ning Y, Mayer RJ, Stone RM, Larson RA, Bloomfield CD.: Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. Blood. 108:63-73. 2006.

Reader J.C., Zhao F.X., Butler, M.S., Rapoport, A.P., and Ning, Y.: REL-Positive Double Minute Chromosomes in Follicular Lymphoma. Leukemia 21:842-844. 2007.

Chang H, Qi X, Xu W, Reader JC, Ning Y.: Analysis of 6q deletion in Waldenstrom macroglobulinemia. Eu J Haematol. 79:244-247. 2007

Reader JC, Leng Q, Rassool FV, Ning Y.: Regulation of differentiation by a PHD domain in the NUP98-PHF23 fusion protein. Leuk Res. 34:1094-1097. 2010

Meekins J, Butler M, Skinner M, Shippy R, Greene C, Ning Y.: Microarray analysis of an unbalanced t(4;13) translocation narrows down the trisomy 13 associated polydactyly to a 7 Mb region. Am J Med Genet. 152A:2906-2907. 2010

Yu L, Reader JC, Chen C, Zhao XF, Ha JS, Lee C, York T, Gojo I, Baer MR, Ning Y.: Activation of a novel palmitoyltransferase ZDHHC14 in acute biphenotypic leukemia and subsets of acute myeloid leukemia. Leukemia. 25:367-371. 2010

Yu L, Slovak ML, Mannoor K, Chen C, Hunger SP, Carroll AJ, Schultz RA, Shaffer LG, Ballif BC, Ning Y.: Microarray detection of multiple recurring submicroscopic chromosomal aberrations in pediatric T-cell acute lymphoblastic leukemia. Leukemia. 25:1042-1046. 2011