Bookmark and Share

Jian  Zhang
 

Jian Zhang Ph.D.

Academic Title: Assistant Professor
Primary Appointment: Biochemistry and Molecular Biology
jian@cfs.umaryland.edu
Location: Bio Park 1, N270
Phone: (410) 706-7500
Fax: (410) 706-8408

Personal History:

Educational Background
 
  • 01/2001-01/2003: Postdoctoral Research Associate, Supervisor: Royce W. Murray University of North Carolina at Chapel Hill, North Carolina. 
  • 10/1999-12/2000: Postdoctoral Research, Supervisor: Marye Anne Fox Associate North Carolina State University, Raleigh, North Carolina.
  • 01/1996-03/1999: Ph.D., Supervisor: Masao Kaneko Ibaraki University, Ibaraki, Japan.
  • 09/1988-07/1991: M.S., Supervisor: Xiaohuai Hou, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
  • 09/1982-07/1986: B.S., Supervisor: Xiaohuai Hou, Beijing Normal University, Beijing, China.
Working Experience
 
  • 02/2003-present: Assistant Professor, Center for Fluorescence Spectroscopy (CFS), University of Maryland School of Medicine at Baltimore.
  • 09/1991-01/1995: Research Associate, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.                   
  • 08/1986-08/1988, Instructor, Educational College of Liaoning Province, Shenyang, China.

Research Interests:

  • Synthesis and functionalization of metal nanoparticle-associated fluorophores.
  • Investigation of metal surface enhanced fluorescence properties (intensity, FRET, photostability, photoblinking, etc).
  • Development of sensitive fluorescence bioassay.
  • Single molecular fluorescence behaviors of organic fluorophores on surfaces of metal nanostructures.
  • Fluorescence intensity and lifetime image of cell and single molecule counting on image of single cell .

Publications:

Zhang, J.; Fu, Y; Lakowicz, J. R. Luminescent images of single gold nanoparticles and their labeling on silica beads Optic Express, 2007, 15, 13415-13420.
 
Fu, Y; Zhang, J.; Lakowicz, J. R. Suppressed blinking in single quantum dots (QDs) immobilized near silver island films (SIFs) Chemical Physics Letters, 2007, 447, 96-100.
 
Zhang, J.; Fu, Y.; Chowdhury, M.; Lakowicz, J. R. Metal-enhanced single molecule fluorescence on silver particle monomer and dimer: coupling effect between metal particles Nano Letters 2007, 7, 2101-2107.
 
Zhang, J.; Fu, Y.; Chowdhury, M.; Lakowicz, J. R. Enhanced Forster resonance energy transfer (FRET) on single metal particle 2: dependence on donor-acceptor separation distance, particle size, and distance from metal surface Journal of Physical Chemistry C 2007, 111, 11784-11792..
 
Zhang, J., Fu, Y.; Lakowicz, J. R. Single cell fluorescence imaging using metal-coupled probe Bio-conjugation Chemistry 2007, 18, 800-805.
 
Zhang, J.; Lakowicz, J. R. Metal-enhanced fluorescence of an organic fluorophore using gold particles Optical Express 2007, 15, 2598-2606.
 
Zhang, J.; Fu, Y.; Lakowicz, J. R. Emission behavior of Ru(bpy)32+ complex in silver nanoshell-enhanced self-quenching by metal nanostructure Journal of Physical Chemistry C, 2007, 111, 1955-1961.
 
Zhang, J.; Fu, Y.; Gryczynski, I.; Lakowicz, J. R. Enhanced Forster resonance energy transfer (FRET) on single metal particle Journal of Physical Chemistry C 2007, 111, 50-56.
 
Zhang, J.; Gryczynski, I.; Gryczynski, Z.; Lakowicz, J. R. Dye-labeled silver nanoshell-bright particle Journal of Physical Chemistry B 2006 110, 8986-8991.
 
Zhang, J.; Lakowicz, Joseph J. R. Model DNA detection by metal enhanced fluorescence from immobilized silver nanoparticles on solid substrate Journal of Physical Chemistry B 2006 110, 2387-2392.
 
Zhang, J.; Matveeva, E.; Gryczynski, I.; Leonenko, Z.; Lakowicz, J. R. Metal-enhanced fluoroimmunoassay on a silver film by vapor deposition Journal of Physical Chemistry B 2005, 109, 7969-7975.
 
Zhang, J.; Lakowicz, J. R. Enhanced Luminescence of Phenyl-phenanthridine dye on aggregated small silver nanoparticles Journal of Physical Chemistry B 2005, 109, 8701-8706.
 
Zhang, J.; Malicka, J.; Gryczynski, I.; Leonenko, Z.; Lakowicz, J. R. Surface-enhanced fluorescence of fluorescein-labeled oligonucleotides capped on silver nanoparticles Journal of Physical Chemistry B 2005, 109, 7643-7648.
 
Aslan, K.;Zhang, J.; Lakowicz, J. R.; Geddes, C. D. Saccharide sensing using gold and silver nanoparticles - A review Journal of Fluorescence 2004, 14, 391-400.
 
Zhang, J.; Geddes, C. D.; Lakowicz, J. R. Complexation of polysaccharide and monosaccharide with thiolate boronic acid capped on silver nanoparticle Analytical Biochemistry 2004, 332, 253-260.
 
Zhang, J.; Roll, D.; Geddes, C. D.; Lakowicz, J. R. Aggregation of silver nanoparticle-dextran adducts with concanavalin A and competitive complexation with glucose Journal of Physical Chemistry B 2004, 108,12210-12214.
 
Zhang, J.; Gryczynski, Z.; Lakowicz, J. R. First observation of surface plasmon-coupled electrochemiluminescence Chemical Physics Letters 2004, 393, 483-487.
 
Zhang, J.; Malicka, J.; Gryczynski, I.; Lakowicz, J. R. Oligonucleotide-displaced organic monolayer-protected silver nanoparticles and enhanced luminescent of their salted aggregates Analytical Biochemistry 2004, 330, 81-86.
 
Zhang, J.; Lee, J.K.; Wu, Y.; Murray, R.W. Photoluminescence and electronic interaction of anthracene derivatives adsorbed on sidewalls of single-walled carbon nanotubes Nano Letters 2003, 3, 403-407.
 
Zhang, J.; Whitesell, J.K.; Fox, M. A. Photophysical behavior of variously sized colloidal gold clusters capped with monolayers of an alkylstilbenethiolate Journal of Physical Chemistry B 2003, 107, 6051-6055.
 
Zhang, J.; Wang, G.; Shon, Y.-S.; Zhou, O.; Superfine, R.; Murray, R. W. Interactions of small molecules and Au nanoparticles with solubilized single-wall carbon nanotubes Journal of Physical Chemistry B 2003, 107, 3726-3732.
 
Wang, G; Zhang, J.; Murray, R.W. DNA Binding of an ethidium intercalator attached to a monolayer-protected gold cluster Analytical Chemistry 2002, 74, 4320-4327.
 
Zhang, J.; Whitesell, J.K.; Fox, M. A. Photoreactions of a self-assembled monolayer of azobenzene or stilbene derivatives capped on colloidal gold clusters Chemistry of Materials 2001, 13, 2323-2331.
 
Hu, J.; Zhang, J.; Liu, F.; Kittredge, K; Whitesell, J.K.; Fox, M. A. Competitive photochemical reactivity in a self-assembled monolayer on colloidal gold Journal of American Chemical Society 2001, 123, 1464-1470.