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Stephen R Shorofsky

Stephen R Shorofsky M.D., Ph.D.

Academic Title: Professor
Primary Appointment: Medicine
Additional Title(s): Director of Clinical Electrophysiology Program., Director of the Clinical Electrophysiology Fellowship Program
Location: UMH Room N3W77
Phone: (410) 328-6056
Fax: (410) 328-2062

Research Interests:

My clinical interests are in the area of clinical electrophysiology or management of arrhythmias.  I direct the clinical electrophysiology program at UMMS.  This entails recruitment and mentoring of junior faculty members, supervision of the Electrophysiology staff and supervision of our clinical research activities.  We currently have 5 faculty members, 3 fellows, 8 nurses, 2 research nurses and 4 other support staff.  In our program, I perform all aspects of clinical electrophysiology including ablations ( and simple), pacemaker implants, ICD implants and bi-ventricular implants.  I am particularly interested in the treatment of complex atrial arrhythmias and ventricular arrhythmias. We operate as a consult service in the hospital and have 3 outpatient clinics per week.  I also perform procedures and consults at Mercy Hospital.

My clinical research interests involve the mechanisms of defibrillation, development of new defibrillators, new indications for pacemakers, the role of pacing in sleep apnea, new anti-arrhythmic drugs and the management of ventricular arrhythmias with ablation.  I am involved in many clinical trials including multi-center trials, trials in conjunction with industry and single-center initiated trials.  My basic science interests include the regulation of intracellular calcium and its role in arrhythmias


Shorofsky SR, Peters RW, Rashba EJ, Gold MR. Comparison of step-down and binary-search algorithms for determination of defibrillation threshold in humans. Pacing Clin Electrophysiol. 2004:27(2):218-220.
Rashba EJ, Shorofsky SR, Peters RW, Gold MR. Optimization of atrial defibrillation with a dual-coil, active pectoral lead system. J Cardiovasc Electrophysiol. 2004:15:790-794.
Rashba EJ, Osman AF, MacMurdy K, Kirk MM, Sarang S, Peters RW, Shorofsky SR, Gold MR. Enhanced detection of arrhythmia vulnerability using T wave alternans, left ventricular ejection fraction, and programmed ventricular stimulation: a prospective study in subjects with chronic ischemic heart disease. J Cardiovasc Electrophysiol 2004; 15: 170-176.
Rashba EJ, Gold MR, Crawford FA, Leman RB, Peters RW, Shorofsky SR. Efficacy of transthoracic cardioversion of atrial fibrillation using a biphasic, truncated exponential shock waveform at variable initial shock energies. Am J Cardiol 2004; 94(12):1572-4.
Rashba EJ, Shorofsky SR, Brown T, Peters RW, Gold MR. Clinical predictors of atrial defibrillation thresholds with a dual coil, active pectoral lead system. Heart Rhythm 2005, 2:49-54.
Olshansky B., Sami M, Rubin A, Kostis J, Shorofsky S, Slee A, Greene HL. Use of amiodarone for atrial fibrillation in patinents with preexisting pulmonary disease in the AFFIRM study. Am J Cardiol 2005, 495:404-405.
Voudouris AA, Khan EM, Hood RE, Shorofsky SR. Migration of an Accufix atrial lead retention wire to the anterior mediastinum. Heart Rhythm 2005, 2:215.
Shorofsky SR, Rashba E, Havel W, Belk P, Degroot P, Swerdlow C, Gold MR. Improved defibrillation efficacy with an ascending ramp waveform in humans. Heart Rhythm 2005, 2:388-394.
Khan EM, Voudouris AA, Hood RE, Shorofsky SR. Repositioning of a dislodged and fibrosed ventricular lead. J Interventional Card Electrophysiol 2005,13:1-3.