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Anthony A Gaspari
 

Anthony A Gaspari M.D.

Academic Title: Professor
Primary Appointment: Dermatology
Secondary Appointments: Microbiology and Immunology, Pharmacology
Administrative Title: Chair
Additional Title(s): Albert Shapiro, MD, Endowed Professorship in Dermatology
agasp001@umaryland.edu
Location: 419 W. Redwood Street – Ste 240 Baltimore MD 21201
Phone: (410) 328-5767
Fax: (410) 328-0098
Lab: (410) 706-1184

Research Interests:

T-lymphocyte mediated allergic skin diseases, antigen presentation by resident epidermal cells such as Langerhans cells and keratinocytes to skin homing lymphocytes, and immunopharmacology


Publications:

Fishelevich R, Malanina A, Luzina I, Atamas S, Smyth MJ, Porcelli SA, Gaspari AA. Ceramide-Dependent Regulation of Human Epidermal Keratinocyte CD1d Expression During Terminal Differentiation. J. Immunol. (submitted, 2005)

Niculescu F, Niculescu T, Nguyen P, Puliaev R , Papadimitriou JC, Gaspari AA Rus H and Via CS. Both Apoptosis and Deposition of Complement Membrane Attack Complex are Major Features of Acute Graft-versus Host Disease in the Parent-into-F1 Model. Exp. and Molecular Pathol. (in press 2005)

Roychowdhury S, Vyas PM, Reilly TP, Gaspari AA, Svensson CK Characterization of the Formation and Localization of Sulfamethoxazole and Dapsone-Associated Drug-Protein Adducts in Human Epidermal Keratinocytes . J. Pharmacol. Exp. Therapeutics 314 (1): 43-52, 2005

Burns R, Luzina I, Nasir A, Haidaris CG, Barth RK, Gaspari AA. Keratinocyte-Derived, CD80-Mediated Co-stimulation is Associated with the Development of Hapten-Specific IgE During Contact Hypersensitivity to Th1-dominant haptens. J All. Clin. Imunol. 115(2): 383-90, 2005

Wakem P, Ramirez F, Zlotnick D, Gaspari AA. Heterogeneity of Human Keratinocyte Responses to Allergens and Irritants in an In vitro Assay for CD80 Transcription. J. Appl. Toxicol. 24:485-92, 2004

Cummins DL, Gaspari AA. Photoprotection by Thalidomide in Patients with Chronic Cutaneous Lupus Erythematosus: Discordant Effects on Minimal Erythema Dose and Sunburn Cell Formation. Br.J. Derm. 151(2):458-64, 2004

Lu KQ, Brenneman S, Burns R., Jr., Vink A, Gaines E, Haake A, Gaspari AA. Thalidomide Inhibits Inhibits UVB-Induced Mouse Keratinocytes Apoptosis by a TNF-
Dependent Pathway. Photoderm. Photoimmunol. Photomed. 19: 272-80, 2003

Gaspari AA. Topical Immune Response Modifiers: Mechanism of Action and Clinical Implications. Internal Medicine World Report 18(6): 2-10; 2003

Gaspari AA, Burns RP, Jr., Ferbel B, Tanck C, Bedi GS, Perrella FW. Bacterial Protease Treatment of Natural Rubber Latex Alters its Primary Immunogenicity in a Mouse Model of Sensitization. Clin. Immunol. 105(1): 9-16, 2002