Research Interests
Dr. Temoshok is Principal Investigator of a 5-year NIH-funded study (through October 2009), Elucidating the Biopsychosocial Mediators of HIV Progression. This study builds upon her extensive prior work as an international leader in the field known as psychoneuroimmunology (PNI), which explores the multiple complex interrelationships among the mind, the central nervous system, the immune system, and the outcome of immunologically mediated diseases. In her previous appointment at the University of California San Francisco School of Medicine (UCSF), she directed a decade-long program of research on PNI and cancer progression. In 1982, she was in the first small group of scientists to receive a federal grant to study the newly- recognized disease that would eventually be called AIDS. AT UCSF, she created and directed the multidisciplinary Biopsychosocial AIDS Project, researching the role of PNI linkages in HIV and AIDS progression, as well as the psychosocial and neuropsychological sequella of HIV infection.
Dr. Temoshok’s second major clinical research interest is HIV exposure and transmission behavioral risk prevention. Dr. Temoshok is currently serving a 4-year term on the CDC/HRSA Advisory Committee on HIV and STD Prevention, appointed by the Secretary of Health and Human Services. She is also PI of a 5-year CDC/DHMH-funded project on Integrating HIV Prevention in Primary Care Settings Serving HIV Positive Individuals. This project is the culmination of her prior work as Scientific Director of behavioral prevention research for the U.S. Military's HIV Research Program, where she developed and conducted a probability survey of more than 18,000 soldiers, one of the largest HIV risk behavior surveys conducted in the US. Dr. Temoshok was also among the first HIV researchers to emphasize the concern about secondary transmission of HIV, and to document significant levels of transmission risk behavior among infected individuals.
From 1994 to 1997, Dr. Temoshok served as a liaison between the World Health Organization's Vaccine Unit in Geneva and the US Military's vaccine preparedness studies in Thailand, focusing on behavioral issues. She also served as Senior Scientist with the Division of Mental Health at WHO and as a UNAIDS consultant, developing global programs and policy for HIV prevention in military populations, a report and global policy recommendations for neurocognitive impairment in early HIV infection, as well as an international assessment for Quality of Life among persons living with HIV/ AIDS. This latter work stimulated another line of research at the University of Maryland on the health implications of forgiveness (e.g., on medical adherence, health outcomes, and transmission risk behaviors) in persons living with HIV/AIDS.
Publications
Temoshok L., Baum A. (Eds). Psychosocial perspectives on AIDS: Etiology, prevention, and treatment. Englewood Cliffs, NJ: Lawrence Erlbaum; 1990.
Solomon GF, Kemeny M, Temoshok L. Psychoneuroimmunologic aspects of Human Immunodeficiency Virus infection. In R Ader, DL Felten, N Cohen (Eds.),
Psychoneuroimmunology II. Orlando, FL: Academic Press, 1991:1081-1113.
Temoshok L, Dreher H. The Type C connection: The behavioral links to cancer and your health. New York: Random House, 1992.
Temoshok L. HIV/AIDS, psychoneuroimmunology, and beyond: A commentary and review. Advances in Neuroimmunology 1993; 3: 87-95.
Temoshok L. Behavioral research contributions to planning and conducting HIV vaccine efficacy studies. AIDS Research and Human Retroviruses 1994; 10: S227-S280.
Temoshok L. On biobehavioral models of cancer, stress, and disease course. American Psychologist 1995; 50: 1104-1105.
Temoshok L, Patterson T. Risk of HIV transmission in infected US military personnel. The Lancet 1996; 347, 697-698.
Temoshok L. HIV/AIDS. In H Friedman (Ed.), Encyclopedia of Mental Health, Vol. 2. San Diego: Academic Press; 1998: 375-392.
Temoshok L. Psychological response and survival in breast cancer. The Lancet 2000; 355: 404-405.
Temoshok L. Complex coping patterns and their role in adaptation and neuroimmunomodulation: Theory, methodology, and research. Annals NY Academy of Science 2000; 917: 446-455.
Temoshok, L.R., Wald, R.L. Change is complex: Rethinking research on psychosocical interventions and cancer. Integrative Cancer Therapies 2002; 1: 135-145.
Solano L, Costa M., Temoshok L., et al. An emotionally inexpressive (Type C) coping style influences HIV disease progression at six and twelve month follow-ups. Psychology & Health 2002; 17: 641-655.
Temoshok L. Connecting the dots linking mind, behavior, and disease: The biological concomitants of coping patterns. Integrative Cancer Therapies 2002; 1: 387-391.
Temoshok L. Type C coping and cancer progression. In R Fernandez-Ballesteros (Ed.) The Encyclopedia of Psychological Assessment, Vol. 2. NY: Sage; 2003: 1052-1056.
Temoshok, L.R. Rethinking theory and research in biopsychosocial oncology. Psycho-Oncology 2004; 13: 460-467.
Temoshok, L.R. Type C coping or behavior pattern. In A.J. Christensen, R. Martin, J.M. Smyth (Eds.) Health Psychology. NY: Plenum; 2004: 1052-1056.
Temoshok, L.R. The biopsychosocial model in health psychology. In A.J. Christensen, R. Martin, J.M. Smyth (Eds.) Health Psychology. NY: Plenum; 2004: pp. 29-32..
Temoshok, L.R.,Wald, R.L. Forgiveness and health in persons with HIV/ AIDS. In E.L. Worthington (Ed.) Handbook of forgiveness. NY: Brunner-Routledge; 2005: 335-348.
