Publications
Selected Publications
Rosenthal, R.E. and Fiskum, G., Oxygen: Could there be too much of a good thing? Hosp Med. 66: 76-77 (2005).
Hainsworth, A.H., Bermpohl, D., Webb, T.E., Darwish, R., Fiskum, G., Qiu, J., McCarthy, D., Moskowitz, M.A., Whalen, M.J., Expression of cellular FLICE inhibitory proteins (cFLIP) in normal and traumatic murine and human cerebral cortex, J. Cereb. Blood Flow Metab. 25: 1030-1040 (2005).
Chinopoulos,C., Starkov, A.A., Grigoriev, S., Dejean, L.M., Kinnally, K.W., Liu, X., Ambudkar, I.S., Fiskum, G., Diacylglycerols activate mitochondrial cationic channel(s) and release sequestered Ca(2+), J. Bioenerg. Biomemb. 37: 237-247 (2005).
Mehrabian, Z., Liu, L-I., Fiskum, G., Rapoport, S.I., and Chandrasekaran, K., Regulation of mitochondrial gene expression by energy demand in neural cells, J. Neurochem. 93: 850-860 (2005).
Soane, L. and Fiskum, G., Inhibition of mitochondrial neural cell death pathways by protein transduction of bcl-2 family proteins, J. Bioenerg. Biomemb. 37: 179-180 (2005).
Soane, L. and Fiskum, G., TAT-mediated endocytotic delivery of the loop deletion Bcl-2 protein protects neurons against cell death, J. Neurochem. 95: 230-243 (2005).
Schuh, R.A., Kristian, T., Gupta, R.K., Flaws, J.A., and Fiskum, G., Methoxychlor inhibits brain mitochondrial respiration and increases hydrogen peroxide production and CREB phosphorylation, Toxicol Sci. 88: 495-504 (2005).
Robertson, C.L., Puskar, A., Hoffman, G.E., Murphy, A.Z., Saraswati, M., and Fiskum G., Physiologic progesterone reduces mitochondrial dysfunction and hippocampal cell loss after traumatic brain injury in female rats, Exp. Neurol., 197:235-243 (2006)
Richards, E.M., Rosenthal, R.E., Kristian, T., and Fiskum, G., Postischemic hyperoxia reduces hippocampal pyruvate dehydrogenase activity, Free Rad. Biol. Med. 40: 1960-1970 (2006)
Vereczki, V., Martin, E., Rosenthal, R.E., Hof, P.R., Hoffman, G.E., and Fiskum, G., Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death, J. Cereb. Blood Flow Metab., 26: 821-35 (2006).
Bambrick, L., Wright, C., and Fiskum, G., Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons, J. Bioenerg. Biomemb. 38:43-47 (2006).
Balan, I.S., Fiskum, G., Hazelton, J., Cotto-Cumba, C., and Rosenthal, R.E., Oximetry-guided reoxygenation improves neurological outcome after experimental cardiac arrest, Stroke 37: 3008-3013 (2006).
Chandrasekaran, K., Hazelton, J., Wang, Y., Fiskum, G., and Kristian, T., Neuron-specific conditional expression of a mitochondrially targeted fluorescent protein in mice, J. Neurosci. 26: 13123-13127 (2006).
Kahraman, S. and Fiskum, G., Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and astrocytes, Neurochem. Res. 32: 799-806 (2007).
Mehrabian, Z., Chandrasekaran, K., Kristian, T., Fiskum, G., and Kalvakolanu, D.B., The interferon β and retinoic acid induced cell death regulator GRIM-19 are upregulated during focal cerebral ischemia, J. Interferon Cytokine Res. 27: 383-392 (2007).
Richards, E.M., Fiskum, G., Rosenthal, R.E., Hopkins, I., and McKenna, M.C., Hyperoxic reperfusion following global ischemia decreases hippocampal energy metabolism, Stroke. 38: 1578-1584 (2007).
Robertson, C.L., Saraswati, M., and Fiskum, G., Mitochondrial dysfunction early after traumatic brain injury in immature rats, J. Neurochem. 101: 1248-1257 (2007).
Carlson, D.E., Nguyen, P.X., Soane, L., Fiedler, S.M., Fiskum, G., Chiu, W.C., Scalea, T.M. , Hypotensive hemorrhage increases calcium uptake capacity and Bcl-XL content of liver mitochondria. Shock. 27: 192-198 (2007).
Kristian, T., Pivovarova, N.B., Fiskum, G., Andrews, S.B., Calcium-induced precipitate formation in brain mitochondria: composition, calcium capacity, and retention. J. Neurochem. 102:1346-1356 (2007)