Nanette  I Steinle
 

Nanette I Steinle M.D.

Academic Title: Assistant Professor
Primary Appointment: Medicine
nsteinle@medicine.umaryland.edu
Location: Howard Hall, Room 467
Phone: (410) 706-1512
Fax: (410) 706-6146
Lab: (410) 706-4749

Personal History

Dr. Steinle completed her undergraduate training in nutrition prior to completing her medical degree. She completed an internal medicine residency and endocrinology fellowship at the University of Maryland in Baltimore.

Dr. Steinle's major research interests are directed at understanding the molecular and genetic aspects of blood-pressure regulation, obesity, metabolic syndrome and eating behavior. Dr. Steinle is currently exploring genes and genetic variants on chromosome 2 that influence blood-pressure regulation. She is also interested in unraveling the genetic contribution to salt sensitive hypertension.

Dr. Steinle published the first genome-wide scan of eating behavior traits. She demonstrated that eating behavior is heritable and that there may be specific genetic loci that regulate eating behavior. Currently she is studying candidate genes that may regulate eating behavior. Her work focuses on the study of genetic variation in taste receptor genes and their role in eating behavior, nutrient intake, diabetes and obesity.

Dr. Steinle is also involved in teaching nutrition in the medical curriculum. She is co-course director of the cell and molecular biology course. She teaches nutrition in the physiology and therapeutics course, as well as in the clinical components of the medical curriculum.

Research Interests

Genetics of complex disease

Taste receptors and metabolic disorders

Genetics of blood-pressure regulation

Clinical Speciality

Diabetes

Nutrition

Endocrinology

Lab Techniques and Equipment

Genome-wide association studies

Publications

Search My Publications in Pub Med

HIGHLIGHTED PUBLICATIONS

Steinle N, Hsueh W-C, Snitker S, Mitchell BD, Pollin T, Sakul H, St.Jean PL, Bell CJ, Shuldiner AR.  Genetics of eating behavior in the Amish:  A Genome Wide Scan and Heritability Study. Am J Clin Nutr 2002;75:1098-1106.

Pollin T, Hsueh W-C, Steinle N, Snitker S, Shuldiner A, Mitchell B. A genome-wide scan of lipid levels in the Old Order Amish. Atherosclerosis 2004; 173: 89-96.

Steinle N, Kazlauskaite R, Imumorin I, Hsueh W-C, Pollin T, O'Connell J, Mitchell B, Shuldiner A.  Variation in the Lamin A/C (LMNA) Gene:  Associations with metabolic syndrome. Arterioscler Thromb Vasc Biol; 2004;24(9):1708-13. Epub 2004 Jun 17.

Steinle N, Pollin T, O'Connell J, Mitchell B, Shuldiner A. Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish. JClin Endocrinol Metab. 2005;90(12):6672-7. Epub 2005 Oct 4.

Patrick F McArdle, Sue Rutherford, Braxton D Mitchell, Coleen M Damcott, Ying Wang, Vasan Ramachandran, Sandra Ott, Yen-Pei C Chang, Daniel Levy and Nanette Steinle. Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study. BMC Medical Genetics 2008, 9:67 (14 Jul 2008)




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