SOM Faculty Profile : Anthony Amoroso

Anthony Amoroso

Anthony Amoroso M.D.

Academic Title: Assistant Professor

Primary Appointment: Medicine

Secondary Appointments: Institute of Human Virology

Additional Title(s): Director, Baltimore VA Hospital HIV Care and Infectious Diseases Clinic;

aamoroso@ihv.umaryland.edu

Location: Institute of Human Virology, N555

Phone: (410) 706-4607

Fax: (410) 706-1992

Lab: Institute of Human Virology

Research Interests

Cyclic Therapy Pilot Study of the Combination Sustiva/3TC/Tenofovir/HU: Can Treatment Targeted at the Resting Cell Pool Cause the Delay of Viral Rebound, Allowing for Improved Strategies of Cyclic Therapy?

A Phase I Pilot Study of an Antiretroviral Bridging Regimen in Highly Experienced Patients Unable to Achieve Viral suppression

A Study to Probe the Safety and Durability of Tenofovir and a Cell Cycle Agent to Maintain Viral Suppression.

Viral Decay Kinetics During Induction Therapy With or Without the Use of Fuzeon in HAART-naïve Patients with Advanced HIV

Cell Cycle Independent Antiretroviral Therapy: Once Daily Combination of Nevirapine, 3TC, and Tenofovir

Publications

· Amoroso A., Davis C., Redfield R “Antiretroviral Therapy In Africa” In EssexM. And Souleymane M, eds. AIDS in Africa 2002.

· Heredia A, Amoroso A, Davis C, et al “Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV Beta chemokines: An approach to suppress R5 strains of HIV-1. PNAS 2003

· Heredia A, Davis C, Amoroso A, Dominique JK, Le N, Klingebiel E, Reardon E, Zella D, Redfield RR. Induction of G1 Cell Cycle Arrest in Peripheral Blood Mononuclear Cells Results in Increased Extracellular Levels of RANTES, MIP-1∞ and MIP-1β: a Strategy to Inhibit Replication of R5 strains of HIV-1. Proc. Nat’l. Acad. Sci. USA, 2003;100:4179-4184

· Gilliam B, Amoroso A, Davis C, Redfield R “The Role of Antiretroviral Therapy in Asia” In Essex M and Yichen L, eds AIDS in Asia 2004

· Amoroso, Anthony; Spencer, Derek E; Redfield, RR. Improving on success: what treating the urban poor in America can teach us about improving antiretroviral programs in Africa. AIDS, 18 Supplement 3:S39-S43, June 2004.

· Heredia A, Davis, CE Jr, Amoroso A, Taylor G, Le N, Bamba D, Redfield RR. In Vitro Suppression of latent HIV-1 activation by Vitamin E: potential clinical implications. AIDS 2005, May 20;19(8):836-7.

Links of Interest

Institute for Human Virology

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