Bookmark and Share

Alash'le  Abimiku

Alash'le Abimiku Ph.D.

Academic Title: Professor
Primary Appointment: Medicine
Secondary Appointments: Epidemiology & Public Health
Additional Title(s): Executive Director, International Research Center of Excellence at the Institute of Human Virology-Nigeria
Location: IHV, N446
Phone: 410-706-1941
Fax: 410-706-1944

Personal History:

Dr. Alash'le Abimiku is a Professor of Medicine Baltimore; and the Executive Director, International Research Center of Excellence at the Institute of Human Virology-Nigeria. Originally from Nigeria, Dr. Abimiku is pivotal to the Institute's success in Nigeria and has remained an international leader in laboratory capacity development in Africa. Dr. Abimiku matriculated from the Ahmadu Bello University, Zaria, Nigeria with a B.S and received her M.Sc. in microbiology and Ph.D. in medical microbiology from the London School of Hygiene and Tropical Medicine, UK.

Research Interests:

Dr. Abimku's research career began in basic vaccine research and HIV disease pathogenesis. She was the first to identify the unique nature of the HIV strain prevalent in Nigeria in 1993 as subtype G1 and later documented the adverse consequences of "mixed" feeding of African infant5,6.

In recent years, she has successfully overlaid her research activity on the significant laboratory capacity she developed in Africa8,9,11,13, which include HIV vaccine preparedness research,10,13 Mother to Child HIV transmission, and  TB-HIV co-infections.7,14. Dr. Abimiku established a containerized BL3 laboratory and molecular TB diagnostic capabilities at the National TB reference laboratory in Nigeria and also continues to study the effect of Lassa virus on HIV infection. 

Additionally, she leads a study on the innate protective factors against HIV in mother to infant transmission and she is the Principal Investigator on two major grants for Nigeria: an NIH-funded H3 Africa Biorepository Initiative designed to support genomic science research in Africa and a CDC-funded laboratory capacity building grant to develop guidelines, curricula, and laboratory trainings in Nigeria. Dr. Abimiku has trained a cadre of pre and postdoctoral Nigerian students through the University of Maryland Institute of Human Virology NIH Fogarty funded AIDS International Training and Research Program Grant who continue to be engaged in advanced research in Nigeria.


  1. Abimiku, A.G., Stern, T.L., Zwandor, A., Markham, P.D., Calef, C., Kyari, S., Saxinger, W.C., Gallo, R.C., Robert-Guroff, M., and Reitz, M.S.: Subgroup G HIV type 1 isolates from Nigeria. AIDS Res. Hum. Retroviruses 10: 1581-1583, 1994.
  2. Abimiku, A.G., Franchini, G., Aldrich, K., Myagkikh, M., Markham, P., Gard, E., Gallo, R.C., and Robert-Guroff, M.: Humoral and cellular immune responses in rhesus macaques infected with human immunodeficiency virus type 2. AIDS Res. Hum. Retroviruses 11: 383-393, 1995.
  3. Abimiku, A.G., Franchini, G., Tartaglia, J., Aldrich, K., Myagkikh, M., Markham, P., Chong, P., Klein, M., Kieny, M-P, Paoletti, E., Gallo, R.C., and Robert-Guroff, M.: HIV-1 recombinant poxvirus vaccine induces cross-protection against HIV-2 challenge in rhesus macaques. Nature Medicine 1: 321-329, 1995.
  4. Aina, O., Dadik J., Charurat M., Amangaman, P., Gurumdi, S., Lar, N., Datong, P., Daniyam, C., Kanki, P., Abimiku, A.G., For the IHV/PSSH APIN study teams. Reference Values of CD4 T-lymphocytes in adult Nigerians. Clinical and Laboratory Diagnostic 12(4): 525-530, 2005.
  5. Maru, S., Datong, P., Selleng, D., Mang, E., Inyang, B., Ajene, A., Guyit, R., Charurat, M., Abimiku, A. Social determinants of mixed feeding behavior among HIV-infected mothers in Jos, Nigeria. Accepted for publication. AIDS Care 21: 1114-1123, 2008.
  6. Charurat M, Datong P, Matawal B, Ajene A, Blattner WA, Abimiku A. Timing and determinants of mother-to-child transmission of HIV in Nigeria. Int J Gynecol Obstet 106: 8-13, 2009.
  7. Abimiku A, Villalba-Diebold, P., Dadik, J., Okolo, F., Mang, E., Charurat, M. Risk factors associated with low CD4+ lymphocyte count among HIV-positive pregnant women in Nigeria. Int J Gynecol Obstet 106: 227-231 2009 doi:10.1016/j.ijgo.2009.03.057 (Epub)
  8. Abimiku, A.G. Building Laboratory Infrastructure to Support Scale-Up of HIV/AIDS treatment, care and prevention. In country experience. Am J Clin Pathol 131:875-886, 2009.
  9. Abimiku AG, Croxton T, Akintunde E, Okelade B, Jugu J, Peters S, Dakum P, Blattner W, Constantine N. Experiences in establishing a PEPFAR-supported laboratory quality system in Nigeria. Am J Clin Pathol 134(4): 541-9, 2010.
  10. Gambo Aliyu, Mukhtar Mohammad, Ahmed Saidu, Prosanta Mondal, Man Charurat, Alash’le Abimiku, Abdulsalami Nasidi and William Blattner. HIV infection awareness and willingness to participate in future HIV vaccine trials across different risk groups in Abuja, Nigeria.  AIDS Care 1- 8 2010 doi:10.1080/09540121003692219 (Epub)
  11. Parsons LM, Somoskövi A, Gutierrez C, Lee E, Paramasivan CN, Abimiku A, Spector S, Roscigno G, Nkengasong J. Laboratory diagnosis of tuberculosis in resource-poor countries: challenges and opportunities. Clin Microbiol Rev 24(2): 314-50, 2011.
  12. Charurat M, Nasidi A, Delaney K, Saidu A, Croxton T, Mondal P, Aliyu GG,Constantine N, Abimiku A, Carr JK, Vertefeuille J, Blattner W. Characterization of acute HIV-1 infection in high-risk Nigerian populations. J Infect Dis. 2012; 15;205(8):1239-47. doi: 10.1093/infdis/jis103. Epub 2012 Feb 21. PubMed PMID: 22357663; PubMed Central PMCID: PMC3308903.
  13. Evaezi Okpokoro, Sophia Osawe, Pam Datong, Aminu Yakubu, Morenike Ukpong, Paul Orhii, John Idoko, Patrick Dakum, Gary Garber and Alash’le Abimiku. Preparing for HIV Vaccine Trials in Nigeria: Building the Capacity of the Community and National Coordinating, Regulatory and Ethical Bodies. J AIDS Clin Res 2013, 4: 12
  14. Nwofor AC, Nyamngee A, Nwabuisi C, Iwakun M, Gidado M, Mensah C, Dakum P, Agbede OO, Ndembi N, Blattner WA, Abimiku AG. Performance of Genotype MTBDRplus in the Detection of Resistance to Rifampicin and Isoniazid Among Clinical Mycobacteria Isolates in Ilorin, Nigeria. Curr HIV Res. 2015;13(4):308-14. PubMed PMID: 25845392.
  15. Abubakar A, Ndembi N, Ogbanufe O, Inalegwu A, Wilson S, Ebagua I, Peters S, Chime C, Dakum P, Abimiku AG. Improved Performance of COBAS AmpliPrep/COBAS TaqMan Version 2.0 Assay Over Amplicor Monitor Version 1.5 in the Quantification of HIV-1 RNA Viral Load in Abuja, Nigeria. Curr HIV Res. 2015;13(4):262-7. PubMed PMID: 25613132.