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James M Gold
Ph.D.
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| Academic Title:
Professor |
| Primary Appointment:
Psychiatry |
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JGOLD@MPRC.UMARYLAND.EDU |
| Location:
701 W. Pratt St.,
388 (MPRC) |
| Phone:
(410) 402-7871 |
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Personal History
Ph.D. 1986, Clinical Psychology, Institute for Advanced Psychological Studies, Adelphi University. Post-Doctoral Fellowship in Neuropsychology, New York Hospital, Cornell Medical Center, Westchester Division 1987.
Research Interests
My current work is focused in three major areas. The first involves studies examining the functional relevance of neurocognitive impairment in schizophrenia, with a particular focus on vocational functioning. We are currently conducting a comprehensive neuropsychological and structural neuroimaging study of good outcome patients as a means of identifying the determinants of successful vocational outcome in schizophrenia . A second area of investigation includes cognitive studies examining different aspects of memory function in schizophrenia. Of particular interest is the nature of working memory impairment in schizophrenia, and the extent to which impairments of working memory may be critical mediators of the generalized deficit observed in schizophrenia. A third area involves more applied studies including clinical treatment trials which use cognitive measures as outcome assessments and work in test validation and test development. This includes work done in the standardization of the WAIS-lll which incorporates a task I developed, letter-number sequencing. Current work includes studies of the clinical validity of the Repeatable Battery for the Assessment of Neuropsychological Status.
Publications
Selected Peer-Reviewed Publications
Gold J, Randolph C, Carpenter C, Goldberg T, Weinberger D. Forms of memory failure in schizophrenia. J Abnorm Psychol 1992; 101:487-494.
Gold J, Randolph C, Goldberg T, Weinberger D. The performance of patients with schizophrenia on the Wechsler Memory Scale-Revised. Clin Neuropsychol 1992; 6:367-373.
Gold J, Harvey P. Cognitive deficits in schizophrenia. Psychiatr Clin North Am 1993; 16:295-312.
Goldberg T, Torrey EF, Gold J, Ragland D, Bigelow L, Weinberger D. Learning and memory in monozygotic twins discordant for schizophrenia. Psychol Med 1993; 71-86.
Gold J, Blaxton T, Hermann B, Randolph C, Fedio P, Goldberg T, Theodore W, Weinberger D. Memory and intelligence in lateralized temporal lobe epilepsy and schizophrenia. Schizophr Res 1995; 59-68.
Goldberg T, Torrey EF, Gold J, Bigelow L, Ragland RD, Taylor E, Weinberger D. Genetic risk of neuropsychological impairment in schizophrenia: a study of monozygotic twins discordant and concordant for the disorder. Schizophr Res 1995; 77-84.
Berman KF, Ostrem JL, Randolph C, Gold J, Goldberg TE, Coppola R, Carson RE, Herscovitch P, Weinberger DR. Physiological activation of a cortical network during performance of the Wisconsin Card Sorting Test: a positron emission tomography study. Neuropsychologia 1995; 33:1027-1046.
Gold J, Berman K, Randolph C, Goldberg T, Weinberger D. PET validation of a novel prefrontal task: Delayed Response Alternation. Neuropsychology 1996; 10:3-10.
Gold J, Carpenter C, Randolph C, Goldberg T, Weinberger D. Auditory working memory and the Wisconsin Card Sorting Test performance in schizophrenia. Arch Gen Psychiatry 1997; 54:159-165.
Binks SW, Gold JM. Differential cognitive deficits in the neuropsychology of schizophrenia. Clin Neuropsychol 1998; 12:8-20.
Bellack AS, Gold JM, Buchanan RW. Cognitive rehabilitation for schizophrenia: problems, prospects, and strategies. Schizophr Bull 1999; 25:257-274.
Gold, JM, Queern C, Iannone VN, Buchanan RW. The RBANS as a screening test in schizophrenia: I. Sensitivity, reliability and validity. Am J Psychiatry 1999; 156:1944-1950.
Hobart MP, Goldberg R, Bartko JJ, Gold JM. The RBANS as a screening test: II. Convergent/discriminant validity and diagnostic group comparisons. Am J Psychiatry 1999; 156:1951-1957.
Gold JM, Bish JA, Iannone VN, Hobart MP, Queern CA, Buchanan RW. Effects of contextual processing on visual conditional associative learning in schizophrenia. Biol Psychiatry 2000; 48:406-414.
Carpenter WT, Gold JM, Lahti AC, Queern CA, Conley RR, Bartko JJ, Kovnick J, Applebaum PS. Decisional capacity for informed consent in schizophrenia research. Arch Gen Psychiatry 2000; 57:533-538.
Gold JM, Rehkemper G, Binks SW, Carpenter CJ, Fleming K, Goldberg TE, Weinberger DR. Learning and forgetting in schizophrenia. J Abnorm Psychol 2000; 109:534-538.
Tek C, Gold J, Blaxton T, Wilk C, Buchanan RW. Visual perceptual and working memory impairments in schizophrenia. Arch Gen Psychiatry 2002; 59:146-153.
Wilk CM, Gold JM, Bartko JJ, Dickerson F, Fenton WS, Knable M, Randolph C, Buchanan RW. Test-retest stability of the repeatable battery for the assessment of neuropsychological status in schizophrenia. Am J Psychiatry 2002; 159:838-844.
Gold JM, Goldberg RW, McNary SW, Dixon LB, Lehman AF. Cognitive correlates of job tenure among patients with severe mental illness. Am J Psychiatry 2002; 159:1395-1402.
Carpenter WT, Gold JM. Another view of therapy for cognition in schizophrenia. Biol Psychiatry 2002; 51:969-971.
Dickinson D, Iannone VN, Wilk CM, Gold JM. General and specific cognitive deficits in schizophrenia. Biol Psychiatry 2004; 55:826-833.
Keefe RS, Goldberg TE, Harvey PD, Gold JM, Poe MP, Coughenour L. The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery. Schizophr Res 2004; 68:283-297.
Gold JM. Cognitive deficits as treatment targets in schizophrenia. Schizophr Res 2004; 72:21-28.
Fuller RL, Luck SJ, McMahon RP, Gold JM. Working memory consolidation is abnormally slow in schizophrenia. J Abnorm Psychol 2005; 114:279-290.
Wilk CM, Gold JM, McMahon RP, Humber K, Iannone VN, Buchanan RW. No, it is not possible to be schizophrenic yet neuropsychologically normal. Neuropsychology 2005; 19(6):778-786.
Keefe RS, Young CA, Rock SL, Purdon SE, Gold JM, Breier A; HGGN Study Group. One-year double blind study of the neurocognitive efficacy of olanzapine, risperidone, and haloperidol in schizophrenia. Schizophr Res 2006; 81(1):1-15.
Saperstein AM, Fuller RL, Avila MT, Adami H, McMahon RP, Thaker GK, Gold JM. Spatial working memory as a cognitive endophenotype of schizophrenia: assessing risk for pathophysiological dysfunction. Schizophr Bull 2006; 32(3):498-506.
Velligan DI, Kern RS, Gold JM. Cognitive rehabilitation for schizophrenia and the putative role of motivation and expectancies. Schizophr Bull 2006; 32(3):474-485.
Shepard PD, Holcomb HH, Gold JM. Schizophrenia in translation: the presence of absence: habenular regulation of dopamine neurons and the encoding of negative outcomes. Schizophr Bull 2006; 32(3):417-421.
Fuller RL, Luck SJ, Braun EL, Robinson BM, McMahon RP, Gold JM. Impaired control of visual attention in schizophrenia. J Abnorm Psychol 2006; 115(2):266-275.
Luck SJ, Fuller RL, Braun EL, Robinson B, Summerfelt A, Gold JM. The speed of visual attention in schizophrenia: electrophysiological and behavioral evidence. Schizophr Res 85(1-3):174-195.
Gold JM, Fuller RL, Robinson BM, McMahon RP, Braun EL, Luck SJ. Intact attentional control of working memory encoding in schizophrenia. J Abnorm Psychol 2006; 115(4):658-673.
Avila MT, Robles O, Hong LE, Blaxton TA, Myers CS, Wonodi I, Gold J, Thaker GK. Deficits on the Continuous Performance Test (CPT) within the schizophrenia spectrum and the mediating effects of family history of schizophrenia. J Abnorm Psychol 2006; 115(4):771-778.
Heerey EA, Robinson BM, McMahon RP, Gold JM. Delay discounting in schizophrenia. Cognit Neuropsychiatry 2007; 12(3):213-221.
Keefe RSE, Bilder RM, Davis SM, Harvey PD, Palmer BW, Gold JM, Meltzer HY, Green MF, Capuano G, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, Davis CE, Hsiao JK, Liberman JA for the CATIE Investigators and the Neurocognitive Working Group. Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial. Arch Gen Psychiatry 2007; 64(6):633-647.
Heerey EA, Gold JM. Patients with schizophrenia demonstrate dissociation between affective experience and motivated behavior. J Abnorm Psychol 2007; 116(2):268-278.
Dickinson D, Ramsey MB, Gold JM. Overlooking the obvious: a meta-analytic comparison of digit symbol and other cognitive measures in schizophrenia. Arch Gen Psychiatry 2007; 64(5):532-542.
Waltz JA, Frank MJ, Robinson BM, Gold JM. Selective reinforcement learning deficits in schizophrenia support predictions from computational models of striatal-cortical dysfunction. Biol Psychiatry 2007; 62(7):756-764.
Waltz JA, Schweitzer JB, Gold JM, Kurup PK, Ross TJ, Salmeron BJ, Rose EJ, McClure SM, Stein EA. Patients with schizophrenia have a reduced neural response to both unpredictable and predictable primary reinforcers. Neuropsychopharmacol 2008, [Epub ahead of print] PMID:
19052540.
Fuller RL, Luck SJ, Braun EL, Robinson BM, McMahon RP, Gold JM. Impaired visual working memory consolidation in schizophrenia. Neuropsychology 2009; 23(1):71-80.
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