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Otha  Myles

Otha Myles M.D.

Academic Title: Clinical Assistant Professor
Primary Appointment: Medicine
Location: 725 West Lombard Street, S315
Phone: 410-706-4637
Fax: 410-706-1992

Personal History:


1990: BS, Howard University, Physician Assistant
1998: MD, University of Maryland School of Medicine

Post Graduate Education and Training

1998-2001: Internal Medicine Internship & Residency, Walter Reed Army Medical Center (WRAMC)
2002-2005: Infectious Disease Fellowship, WRAMC


1990: Primary Care Certificate, Physician Assistant
2001: American Board of Internal Medicine Diplomate, Internal Medicine
2006: American Board of Internal Medicine Diplomate, Infectious Disease

Research Interests:

2002: Sub-Investigator on IND protocol for the use of ribavarin in treating patients from the Balkans with suspected hemorrhagic fever. Landstuhl Regional Medical Center, Landstuhl, Germany.

2003-2005: Principal Investigator (ID fellow) of behavior research study involving knowledge, beliefs and attitudes of HIV+ individuals regarding smallpox.

Principal Investigator (ID Fellow) of multi-site study in collaboration with investigators at WRAIR to define the association of polymorphisms in the MDR1 gene with clinical response to efavirenz in HIV-1 infected military patients stratified by ethnic self-reporting. WRAMC, Washington, DC.

Member (ID Fellow) of the Walter Reed Clinical Leishmaniasis Group Protocol investigating "Sodium Stibogluconate Treatment of Leishmaniasis." Clinical Presentations of Cutaneous Leishmaniasis in U.S. Military Deployed to Iraq.  The American Society of Tropical Medicine and Hygiene, 53RD Annual Meeting, Miami Beach, Florida, 7-11 November, 2004.

2004-2009: Associate Investigator (ID Fellow) on protocol, "Tissue Banking of Biopsy Samples for the Validation of Molecular Assays for the Diagnosis of Leishmaniasis" at WRAMC.

2005-2008: Associate Investigator, RV 158, "A Phase I Double-Blind, Randomized, Dose Escalating, Placebo-Controlled, Study of Safety and Immunogenicity of WRAIR/NIH Live Recombinant MVA-CMDR (HIV-1 CM235 env/CM240 gag/pol) Administered by Intramuscular (IM) or Intradermal (ID) Route In HIV-Uninfected Adults."

2006-2009: Associate Investigator, RV 151, "A Phase I Study of Safety and Immunogenicity of the WRAIR HIV-1 Vaccine Lfn-p24 administered by the Intramuscular (IM) Route in Healthy Adults."

Associate Investigator, "Phase 1 Trial To Evaluate The Safety and Immunogenicity of a Trivalent HIV-1, +/-IL15, MVA Boost Vaccine."

Associate Investigator, RV 179, "Collection and Processing of Blood from Healthy Donors for In Vitro Research�

Associate Investigator, RV 177, "Surveillance of HIV Infection among Civilian Applicants for U.S. Military Service and U.S. Department of Defense Military Personnel."

2007-2009: Associate Investigator, RV 161, "Seroepidemiologic Case-Control Study of HIV-1 Infected and Non-Infected U.S. Military Service Members."

Associate Investigator, RV 190, "A Seroepidemiologic Investigation of HIV-1 Seroconversions among U.S. Military Servicemembers Deployed to Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) 2001-2005."

Principal Investigator, "Molecular Epidemiology of HIV-1 in Bulgaria."

Principal Investigator, "Molecular Epidemiology of HIV-1 in Romania."

2010-present: Member, Institutional Review Board

Clinical Speciality:

Infectious Diseases; HIV


Peer-Reviewed Journal Articles

Myles O, Thomas WJ, Daniels JT, Aronson N. Infected Endovascular Stents Managed With Medical Therapy Alone. Catheter Cardiovasc Interv 2000; 51:471-476.

Belford A, Myles O, Magill A, Wang J, Myhand RC, Waselenko JK. Thrombotic Microangiopathy (TMA) and Stroke     Due to Human Herpesvirus-6 (HHV-6) Reactivation in an Adult Receiving High-Dose Melphalan with Autologous Peripheral Stem Cell Transplantation. Am J Hematol 2004;76:156-162.

Myles, O, Wortmann GW, Cummings JF, Barthel RV, Patel S, Crum-Cianflone NF, Negin NS, Weina PJ, Ockenhouse CF, Joyce DJ, Magill AJ, Aronson NE, Gasser RA Jr.  Visceral leishmaniasis: clinical observations in 4 US army soldiers deployed to Afghanistan or Iraq, 2002-2004. Arch Intern Med 2007;167(17):1899-901.

Hakre S, Peel SA, O'Connell RJ, Sanders-Buell EE, Jagodzinski LL, Eggleston JC, Myles O, etc. Transfusion-transmissible viral infections among US military recipients of whole blood and platelets during Operation Enduring Freedom and Operation Iraqi Freedom. Transfusion 2011 Mar;51(3):473-85.

Non Peer-Reviewed Journal Articles

Myles O, Wortmann GW, Cummings JF, Barthel RV, Patel S, Crum-Cianflone NF, Negin NS, Weina PJ, Ockenhouse CF, Joyce DJ, Magill AJ, Aronson NE, Gasser RA. Two Cases of Visceral Leishmaniasis in U.S. Military Personnel - Afghanistan, 2002-2004. MMWR 2004;53:2:265-268.

Abstracts and/or Proceedings

Infected endovascular palmaz stents successfully managed with medical therapy alone.  Podium Presentation at the American College of Physicians-American Society of Internal Medicine Army Region Scientific Meeting, San Antonio, Texas, 1999.

Knowledge, Beliefs and Attitudes among HIV-1 infected  Military Beneficiaries Regarding Smallpox Disease and Vaccination.  Myles O, Hawkes C, Cameron A, Flaks H, Howard R, Aronson N.  Poster Presentation at Eight Annual Meeting of the Institute of Human Virology, Baltimore, MD, September 29 - October 3, 2003.

Impact of race on time to virologic failure in HIV-1 infected patients receiving efavirenz based therapy.  O Myles, PH. Conference, Bangkok, Thailand, July 11-16, 2004.

Visceral leishmaniasis in U.S. Army Soldiers Deployed to Afghanistan and Iraq.  O Myles, J Cummings, G Wortmann, S Patel, R Vincent Barthel, P Weina, N Crum, C Ockenhouse, A J Magill, N Aronson, RA Gasser.  Late breaker oral presentation in clinical tropical medicine.  The American Society of Tropical Medicine and Hygiene, 53rd Annual Meeting, Miami Beach, Florida, November 7-11, 2004.

Paecilomyces lilacinus infection in a post-lung transplant patient taking campath-1H.  J Woodrow, O Myles, D. Craft, C Ockenhouse.  54th American Society of Tropical Medicine and Hygiene Annual Meeting, Washington, DC, December 11-15, 2005.  (Poster)