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Scott E. Devine

Scott E. Devine Ph.D.

Academic Title: Associate Professor
Primary Appointment: Medicine
Location: Biopark II, 615
Phone: (410) 706-2343

Personal History:

Scott Devine is a faculty member at the Institute for Genome Sciences (IGS) and an Associate Professor of Medicine at the University of Maryland School of Medicine in Baltimore, Maryland. He is primarily interested in human genome variation and how such variation affects human health.

1987-1993: Doctor of Philosophy, Molecular and Cell Biology, University of Maryland, Baltimore
1993-1999: Postdoctoral Fellow, Johns Hopkins University School of Medicine
2000-2009: Assistant Professor, Emory University School of Medicine
2009-present:  Associate Professor, Institute for Genome Sciences and Dept. of Medicine, University of Maryland School of Medicine

Research Interests:

Human genetic variation; Transposable elements in humans and model organisms


The 1000 Genomes Project Consortium (including, Devine, S.E.) (2012) An integrated map of genetic variation from 1,092 human genomes.  Nature 491, 56-65.  PMID: 23128226.

Mills, R.E., Pittard, W.S., Mullaney, J.M., Farooq, U., Creasy, T.H., Mahurkar, A.A., Kemeza, D.M., Strassler, D.S., Ponting, C.P., Webber, C., and Devine, S.E. (2011) Natural genetic variation caused by small insertions and deletions in the human genome.  Genome Res. 21, 830-839. PMID: 21460062.

Mullaney, J.M., Mills, R.E., Pittard, W.S., and Devine, S.E. (2010) Small insertions and deletions (INDELs) in human genomes.  Hum. Mol. Genet. 19, R131-136. PMID: 20858594.

Iskow, R.C., McCabe, M.T., Mills, R.E., Torene, S., Van Meir, E.G., Vertino, P.M., and Devine, S.E. (2010) Natural mutagenesis of human genomes by endogenous retrotransposons. Cell 141, 1253-1261.

Lange, A., McLane, L.M., Mills, R.E., Devine, S.E., and Corbett, A.H. (2010). Expanding the definition of the classical bipartite nuclear localization signal.  Traffic 11, 311-323.

Bennett E.A., Keller H., Mills R.E., Schmidt S., Moran J.V., Weichenrieder O., Devine S.E. (2008) Active Alu retrotransposons in the human genome.  Genome Res. 18(12):1875-83. Epub 2008 Oct 3. PMID: 18836035

McLane L.M., Pulliam K.F., Devine S.E., Corbett A.H. (2008) The Ty1 integrase protein can exploit the classical nuclear protein import machinery for entry into the nucleus.  Nucleic Acids Res. 36(13):4317-26. Epub 2008 Jun 27.

Lange A., Mills R.E., Devine S.E., Corbett A.H. (2008) A PY-NLS nuclear targeting signal is required for nuclear localization and function of the Saccharomyces cerevisiae mRNA-binding protein Hrp1.  J Biol Chem. 283(19):12926-34. Epub 2008 Mar 14.

Mills R.E., Bennett E.A., Iskow R.C., Devine S.E. (2007) Which transposable elements are active in the human genome?  Trends Genet. 23(4):183-91. Epub 2007 Feb 27. Review.

Lange A., Mills R.E., Lange C.J., Stewart M., Devine S.E., Corbett AH. (2007) Classical nuclear localization signals: definition, function, and interaction with importin alpha.  J Biol Chem. 282(8):5101-5. Epub 2006 Dec 14. Review.

Mills R.E., Luttig C.T., Larkins C.E., Beauchamp A., Tsui C., Pittard W.S., Devine S.E. (2006) An initial map of insertion and deletion (INDEL) variation in the human genome.  Genome Res. 16(9):1182-90. Epub 2006 Aug 10.

Mills R.E., Bennett E.A., Iskow R.C., Luttig C.T., Tsui C., Pittard W.S., Devine S.E. (2006) Recently mobilized transposons in the human and chimpanzee genomes.  Am J Hum Genet. 78(4):671-9. Epub 2006 Feb 2.

Bennett E.A., Coleman L.E., Tsui C., Pittard W.S., Devine S.E. (2004) Natural genetic variation caused by transposable elements in humans.  Genetics 168(2):933-51.

Tsui C., Coleman L.E., Griffith J.L., Bennett E.A., Goodson S.G., Scott J.D., Pittard W.S., Devine S.E. (2003) Single nucleotide polymorphisms (SNPs) that map to gaps in the human SNP map.  Nucleic Acids Res. 31(16):4910-6.

Griffith J.L., Coleman L.E., Raymond A.S., Goodson S.G., Pittard W.S., Tsui C., Devine S.E. (2003) Functional genomics reveals relationships between the retrovirus-like Ty1 element and its host Saccharomyces cerevisiae.  Genetics 164(3):867-79.