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Principal Investigators: Dr. Alan Shuldiner, Dr. Nanette Steinle & Dr. Richard Horenstein

The study seeks to understand how levels of plant sterols in the blood differ between participants with one or zero copies of an altered sterol transporter gene. To date, over 304 Amish volunteers have provided blood samples. Our findings suggest that individuals with one copy of the changed sterol transporter gene are not at increased risk for heart disease. We plan to start a new phase of this project in the near future.