UM SOM: Department of Endocrinology

Authors

Publications not listed here can be found by finding the author's faculty profile via the list below, then clicking "Search my publications in Pub Med" under the profile's Publications section.

FACULTY Alan SHULDINER, M.D. Yen-Pei (Christy) CHANG, Ph.D. Yu-Ching CHENG, Ph.D. Coleen M DAMCOTT, Ph.D. Susan K FRIED, Ph.D. Mao FU, M.B.B.S,. Ph.D. Da-Wei GONG, M.D., Ph.D. Richard HORENSTEIN, M.D. Patrick McARDLE, Ph.D. Daniel J McBRIDE, Ph.D. John C McLENITHAN, Ph.D. Braxton MITCHELL, M.P.H, Ph.D. Jeffrey R. O'CONNELL, Ph.D. Afshin PARSA, M.D., M.P.H. Toni POLLIN, Ph.D. Mona M SABRA, M.D. Haiqing SHEN, Ph.D. Kristi SILVER, M.D. Soren SNITKER, M.D., Ph.D. John SORKIN, M.D. Ph.D. Nanette STEINLE, M.D. Elizabeth STREETEN, M.D. Rong-Ze YANG, M.B.B.S., Ph.D, M.D.

Publications     

(Updated:   30 August 2009)

Amish Studies

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In Press:

Kottgen A, Hsu CC, Coresh J, Shuldiner AR, Berthier-Schaad Y, Gambhir TR, Smith MW, Boerwinkle E, Kao WH.  The association of podocinR229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of U S adults. Am J Kidney Dis, in press, 2008.

McArdle PF, Rutherford S, Mitchell BD, Damcott CM, Wang Y, Ramachandran V, Ott S, Chang YPC, Levy D, Steinle N.  Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study BMC Medical Genetics - in press;  (Supplemental Data)

Shen H, Damcott CM, Rampersaud E, Pollin TI, O’Connell JO, Horenstein RB, McArdle PF, Peyser PA, Bielak LF, Post W, Chang Y-PC, Ryan KA, Miller M, Shelton J, Shuldiner AR, Mitchell BD. Apolipoprotein B (APOB) R3527Q is common in the Old Order Amish and is a major cause of increased low density lipoprotein cholesterol concentrations and coronary artery calcification, submitted, (Supplemental Data).

2009

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Cheng Y-C, Kao W-H L, Mitchell BD, O’Connell JR, Shen H, McArdle PF, Gibson Q, Ryan KA, Shuldiner AR, Pollin TI.  Genome-wide association scan identifies variants near matrix metalloproteinase (MMP) geneson chromosome 11q21-22 strongly associated with serum MMP-1 levels.  Circula Genetics - published online May 14, 2009.

McArdle PF, Whitcomb BW, Improper Adjustment for Baseline in Genetic Association Studies of Change in Phenotype.  Human Heredity 67(3):176-182,2009.

Michos ED, Streeten EA, Ryan KA, Rampersaud E, Peyser PA, Bielak LF, Shuldiner AR, Mitchell BD, Post W.  Serum 25-hydroxyvitamin D levels are not associated with subclinical vascular disease or C-reactive protein (CRP) in the Old Order Amish, Calcif Tissue Int (2009) 84:195–202.

Shaffer JR, Kammerer CM, Bruder JM, Cole SA, Dyer TD, Almasy L, MacCluer JW, Blangero J, Bauer RL, Mitchell BD. Quantitative trait locus on chromosome 1q influences bone loss in young Mexican American adults.  Calcif Tissue Internat 84:75-84, 2009.

Wang Y, O'Connell JR, McArdle PF, Wade JB, Dorff SE, Shah SJ, Shi X, Pan L, Rampersaud E, Shen H, Kim JD, Subramanya AR, Steinle NI, Parsa A, Ober CC, Welling PA, Chakravarti A, Weder AB, Cooper RS, Mitchell BD, Shuldiner AR, Chang Y-PC.      Whole-genome association study identifies STK39 as a novel hypertension susceptibility gene. Proc Natl Acad Sci U S A . 2009 Jan 6;106(1):226-31. Epub 2008 Dec 29.

2008

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Arnaud-Lopez L, Usala G, Ceresini G, Mitchell BD, Pilia MG, Piras MG, Sestu N Maschio A, Busonero F, Albai G, Dei M, Lai S, Mulas A, Crisponi L, Tanaka T, Bandinelli S, Guralnik JM, Loi A, Balaci L, Sole G, Prinzis A, Mariotti S, Shuldiner AR, Cao A, Schlessinger D, Uda M, Abecasis GR, Nagaraja R, Sanna S, Naitza S. Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. Am J Human Genet 82:1270-1280, 2008.

Bielak LF, Yu PF, Ryan KA, Rumberger JA, Sheedy, II PF, Turner ST, Shuldiner AR, Mitchell BD, Peyser PA.  Differences in prevalence and severity of coronary artery calcification between two European American populations with diverse lifestyles.   Atherosclerosis 196:888-895, 2008

Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orrù M, Piras MG, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Wang J, Ebrahim S, Sestu N, Duren WL, Spada MC, Stringham HM, Scott LJ, Olla N, Swift AJ, Najjar S, Mitchell BD, Lawlor DA, Smith GD, Ben-Shlomo Y, Andersen G, Borch-Johnsen K, Jorgensen T, Buchanan TA, Shuldiner AR, Lakatta E, Bergman RN, Uda M, Tuomilehto J, Pedersen O, Cao A, Groop L, Mohlke KL, Laaskso M, Schlessinger D, Collins FS, Altshuler D, Abecasis GR, Boehnke M, Scuteri A, Watanabe R.   Variations in the G6PC2/ABCB11 genomic region associated with fasting glucose levels.  J Clin Invest 118, 2620-2628, 2008.

Cole JW, Brown DW, Giles WH, Stine OC, O'Connell JR, Mitchell BD, Sorkin JD, Wozniak MA, Stern BJ, Sparks MJ, Dobbins MT, Shoffner LT, Zappala NK, Reinhart LJ, Kittner SJ.  Ischemic stroke risk, smoking, and the genetics of inflammation in a biracial population: The Stroke Prevention in Young Women Study.  Thrombosis Journal 6:11, 2008.

Douglas JA, Roy-Gagnon M-H, Zhou C, Mitchell BD, Shuldiner AR, Chan H-P, Helvie MA. Mammographic breast density – evidence for genetic correlations with established breast cancer risk factors Cancer Epidemiol Biomarkers Prev, 17:3509-3516, 2008

Guan W, Pluzhnikov A, Cox NJ, Boehnke M.  Meta-analysis of 23 type 2 diabetes linkage studies from the International Type 2 Diabetes Linkage Analysis Consortium.   Hum Hered 66, 35-49, 2008.

Lin P-I, Mitchell BD Approaches for Unraveling the Joint Genetic Determinants of Schizophrenia and Bipolar Disorder.    Schizophrenia Bulletin Advance Access published, May 22, 2008; Schizophrenia Bulletin doi:10.1093/schbul/sbn050.

McArdle PF, Parsa A, Chang Y -PC, Weir MR, O’Connell JR, Mitchell BD, Shuldiner AR.  Association of a Common Nonsynonymous Variant in GLUT9 with Serum Uric Acid Levels in Old Order Amish. Arthritis Rheum 58, 2874-2881, 2008.

Mitchell BD, McArdle PF, Shen H, Rampersaid E, Pollin TI, Bielak LF, Jaquish C, Douglas JA, Roy-Gagnon MH, Sack P, Naglieri R, Hines S, Horenstein RB, Chang Y-.PC, Post W, Ryan KA, Sorkin J, Damcott CM, O’Connell JR, Corretti M, Vogel R, Herzog W, Weir MR, Peyser PA, Shuldiner AR.  The genetic response to short-term interventions affecting cardiovascular function:  Rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study.  Am Heart J 823:828, 2008  

Pollin TI, Damcott CM, Shen H, Ott SH, Shelton J, Horenstein RB, Post W, McLenithan JC, Bielak LF, Peyser PA, Mitchell BD, Miller M, O'Connell JR, Shuldiner AR (2008). A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection. Science, 322, 1702, 2008.

Pollin TI, McBride DJ, Agarwala R, Schaffer AA, Shuldiner AR, Mitchell BD, O’Connell JR.   Investigations of the Y chromosome, male founder structure and YSTR mutation rates in the Old Order Amish.  Hum Hered 65:91-104, 2008.

Rampersaud E, Bielak LF, Parsa A, Shen H, Post W, Ryan KA, Rumberger JA, Sheedy PF II, Peyser PA, Shuldiner AR, Mitchell BD.  The Association of Coronary Artery Calcification and Carotid Artery Intima-Media Thickness with Distinct, Traditional Coronary Artery Disease Risk Factors in Asymptomatic Adults.  Am J Epidemiol, 168:1016-1023,  2008.

Rampersaud E, Mitchell BD, Pollin TI, Fu M, Shen H, O'Connell J, Ducharme JL, Hines S, Sack P, Naglieri R, Shuldiner AR, Snitker S.  Physical Activity and the Association of common FTO Gene Variants with Body Mass Index and Obesity. Arch Intern Med 168:1791-1797,2008  (Supplemental Data)

Roy-Gagnon MH, Weir MR, Sorkin JD, Ryan KA, Sack PA, Hines S., Bielak LF, Peyser PA, Post W, Mitchell BD, Shuldiner AR, Douglas JA.   Genetic influences on blood pressure response to the cold pressor test:  results from the Heredity and Phenotype Intervention Heart Study.  J Hypertens 26:729-736, 2008.

Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen W.-M, Bonnycastle LL., Shen H, Timpson N, Lettre G, Usala G, Chines PS, Stringham HM., Scott LJ, Dei M, Lai S, Albai G, Crisponi L, Naitza S, Doheny KF, Pugh EW, Shlomo YB, Ebrahim S, Lawlor DA, Bergman RN, Watanabe RM, Uda M, Tuomilehto J, Coresh J, Hirschhorn JN, Shuldiner AR, Schlessinger D, Collins FS, DaveySmith G, Boerwinkle E, Cao A, Boehnke M, Abecasis GR, Mohlke KL.  Common variants in the GDF5 - UQCC region are associated with variationin human height. Nat Genet 40, 199-203, 2008.

Streeten EA, McBride DJ, Puffenberger E, Hoffman ME, Pollin TI, Donnelly P, Sack P, Morton H.  Osteoporosis-pseudoglioma syndrome: Description of 9 new cases and beneficial response to bisphosphonates.Bone 43, 584-590, 2008.

Streeten EA, Beck TJ, O’Connell JR, Rampersaud E, McBride DJ, Takala SL, Pollin TI, Usi-Rasi K, Mitchell BD, Shuldiner AR. Autosome-wide linkage analysis of hip structural phenotypes in the Old Order Amish. Bone 43, 607-612, 2008.

Willer CJ, Sanna S, Jackson AU, Scuteri A,  Bonnycastle LL, Clarke R, Heath SC, Timpson NJ, Najjar SS, Stringham HM, Strait J, Duren WL, Maschio A, Busonero F, Mulas A,  Albai G, Swift AJ, Morken MA, Narisu N, Bennett  D, Parish S, Shen H, Galan P, Meneton P, Hercberg S, Zelenika D, Chen W.-M, Li Y, Scott LJ, Scheet PA, Sundvall J, Watanabe RM, Nagaraja R, Ebrahim S,  Lawlor DA, Ben-Shlomo Y, Davey-Smith G, Shuldiner AR, Collins R,  Bergman RN, Uda M, Tuomilehto J, Cao A, Collins FS, Lakatta E, Lathrop GM, Boehnke M, Schlessinger D, Mohlke KL, Abecasis GR.  Newly identified loci that influence lipid concentrations and risk of coronary artery disease.  Nat Genet 40, 161-169, 2008.

2007

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Chu WS, Das SK, Wang H, Chan JC, Deloukas P, Froguel P, Baier LJ, Hanson RL, Jia W, McCarthy MI, Ng MCY., Shuldiner AR, Zeggini E, Elbein SC.  Activating transcription factor 6 (ATF6) sequence polymorphism in type 2 diabetes and prediabetic traits.  Diabetes 56, 856-862, 2007.

de Souza Batista CM, Yang R-Z, Lee M-J, Glynn NM, Yu D-Z, Pray J, Ndubuizu K, Patil S, Schwartz A, Fried SK, Gong D-W, Shuldiner AR, Pollin TI, McLenithan JC.   Omentin plasma levels and gene Expression are decreased in obesity.  Diabetes 56, 1655-1661, 2007.

Fu M, Sabra MM, Damcott C, Pollin TI, Ma L, Ott  S, Shelton JC, Shi X, Reinhart L, O’Connell  JR, Mitchell BD, Baier LJ, Shuldiner AR.   Evidence that rho guanine nucleotide exchange factor 11 (ARHGEF11) on 1q21 is a type 2 diabetes susceptibility gene in the Old Order Amish.   Diabetes 56:1363-1368, 2007.

Hsueh WC, Silver KD, Pollin TI, Bell CJ, O’Connell JR, Mitchell BD, Shuldiner AR.   A genome-wide linkage scan of insulin level derived traits:  the Amish Family Diabetes Study.   Diabetes 56:2643-2648, 2007 .

Ma L, Hanson RL, Que LN, Cali AM, Fu M, Mack JL, Infante AM, Kobes S, Bogardus C, Shuldiner AR, Baier LJ.   Variants in ARGHEF11, a candidate gene for the linkage to type 2 diabetes mellitus on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians.  Diabetes 56, 1454-1459, 2007.

McArdle PF, O’Connell JR, Pollin TI, Baumgarten M, Shuldiner AR, Peyser, PA, Mitchell BD. Accounting for genealogy in family-based genetic association studies.    Hum Hered 64:234-242, 2007.

McArdle PF, Dytch H, O’Connell JR, Shuldiner AR, Mitchell BD, Abney M.   Homozygosity by descent mapping of blood pressure in the Old Order Amish:  evidence for sex specific genetic architecture.   BMC Genet.8:66, 2007.

Njajou OT, Cawthon RM, Damcott CM, Wu S-H, Ott S, Garant MJ, Blackburn EH, Mitchell BD, Shuldiner AR, Hsueh W-C.  Telomere length is paternally inherited and is associated with parental lifespan. PNAS 104:12135-12139, 2007.

Owen KR, Groves CJ, Hanson RL, Knowler WC, Shuldiner AR, Elbein SC, Mitchell BD, Froguel P, Ng MC, Chan JC, Jia W, Deloukas P, Hitman GA, Walker M, Frayling TM, Hattersley AT, Zeggini E, McCarthy MI.  Common Variation in the LMNA Gene (Encoding Lamin A/C) and Type 2 Diabetes:  Association Analyses in 9,518 Subjects.   Diabetes 56(3):879-83,Mar 2007.

Post W, Bielak LF, Ryan KA, Cheng YC, Shen H, Rumberger JA, Sheedy PF II, Shuldiner AR, Peyser PA, Mitchell BD. Determinants of coronary artery and aortic calcification in the Old Order Amish.  Circulation 115(6):717-24, 2007.

Post W, Shen H, Damcott C, Arking DE, Kao WHL, Sack PA,  Ryan KA, Chakravarti A, Mitchell BD,  Shuldiner AR.  Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the Old Order Amish.  Hum Hered 64:214-219, 2007.

Rampersaud E, Damcott CM, Fu M, Shen H, McArdle P, Shi X, Shuldiner AR, Yin J, Chang YP, Ott SH, Zhang L, Zhao Y, Mitchell BD, O’Connell J, Shuldiner AR.  Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish:  evidence for replication from diabetes-related quantitative traits and from independent populations. Diabetes 56:3053-3062, 2007 (pdf); Supplemental Data: (28,307 KB pdf) or (46,136KB Word doc).

Roberts CGP, Shen H, Mitchell BD, Damcott CM, Shuldiner AR, Rodriguez A.  Variants in scavenger receptor class B type I are associated with HDL cholesterol levels in younger women.   Hum Hered 54:107-113, 2007.

Silver KD, Shi X, Mitchell BD.  Betacellulin variants and type 2 diabetes in the Old Order Amish.  Experimental and Clinical Endocrinology & Diabetes  115:229-231, 2007.

Shen H, Bielak LF, Streeten EA, Ryan KA, Rumberger JA, Sheedy PF II, Shuldiner AR, Peyser PA, Mitchell, BD.  Relationship between vascular calcification and bone mineral density in the Old-Order Amish.  Calcif. Tissue Int. 80, 244-250, 2007.

Presentations at American Society of Human Genetics 2007 meeting.  ASHG_2007_Amish_Presentations.doc

2006

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Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver K, Mitchell BD, Shuldiner AR.  Polymorphisms in the transcription factor 7-like 2 (TCF7L2)gene are associated with type 2 diabetes in the Amish: Replication and evidence for a role in both insulin resistance and insulin secretion.  Diabetes 55: 2654-2659, 2006

McArdle PF, Pollin TI, O’Connell JR, Sorkin JD, Agarwala R, Schäffer AA, Streeten EA, King TM, Shuldiner AR, Mitchell BD.  Does having children extend lifespan?  A genealogical study of parity and longevity in the Amish.   J Gerontol A Biol Sci Med Sci 61: 90-95, 2006.

Streeten EA, McBride DJ, Pollin TI, Ryan KA, Shapiro J, Ott S, Mitchell BD, Shuldiner AR, O’Connell JR.  Quantitative trait loci for bone mineral density identified by genome-wide linkage scan to chromosomes 7q and 21q in men from the Amish Family Osteoporosis Study.  J Bone Miner Res 21:1433-1442, 2006 .

Zeggini E, Damcott C, Karim MA, Rayner NW, Groves CJ, Baier LJ, Cox NJ, Hale TC, Hanson RL, Hattersley AT, Hitman GA, Hunt SE, Knowler WC, Mitchell BD, Ng MCY, O’Connell J, Pollin TI, Prochazka M, Vaxillaire M, Walker M, Wang X, Whittaker P, Xiang K, Jia W, Chan JC, Froguel P, Bogardus C, Deloukas P, Shuldiner AR, Elbein SC, McCarthy MI, for the International type 2 diabetes 1q consortium.  Variation within the gene encoding the Upstream Stimulatory Factor 1 (USF1) does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.   Diabetes 55: 2541-2548, 2006

2005

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Brown LB, Streeten EA, Shapiro JR, McBride D, Shuldiner AR, Peyser PA, Mitchell BD.  Genetic and environmental influences on bone mineral density in pre- and post-menopausal women.   Osteoporosis Internat 16:1849-1856, 2005.

Damcott CM, Ott SH, Pollin TI, Reinhart LJ, Wang J, O'Connell JR, Mitchell BD, Shuldiner AR.  Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish.  Diabetes 54:2245-50, 2005.

Mentuccia D, Thomas MT, Coppotelli G, Reinhart L, Mitchell BD, Shuldiner AR, Celi FS.  The Thr92Ala deiodinase type 2 polymorphism is not associated with indexes of insulin resistance in the Old Order Amish.  Thyroid 15: 1223-1227, 2005.

Pollin TI, Tanner K, O'Connell JR, Ott SH, Damcott CM, Shuldiner AR, McLenithan JC, Mitchell BD.  Linkage of plasma adiponectin levels to 3q27 explained by association with variation in the APM1 gene.  Diabetes 54:268-274, 2005.

Sabra M, Damcott C, Fu M, Ott S, O'Connell J, Mitchell BD, Shuldiner AR.  Vesicle-associated membrane protein 4 (VAMP4), a positional candidate gene on 1q24-q25, is not associated with type 2 diabetes in the Old Order Amish.  Molec Genetics Metab 85:133-139, 2005 .

Sorkin J, Post W, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR.  Exploring the genetics of longevity in the Old Order Amish.   Mech Aging Dev 126:347-350, 2005.

Steinle NI, Pollin TI, O’Connell JR, Mitchell BD, Shuldiner AR.  Variants in the ghrelin gene are associated with metabolic syndrome and related traits in the Old Order Amish.  J Clin Endo & Metabolism 90(12):6672-6677, 2005

Streeten, EA, Ryan KA, McBride D, Pollin TI, Shuldiner AR, Mitchell BD.  The relation between parity and bone mineral density in women characterized by a homogeneous lifestyle and high parity.  J Clin Endocrinol Metab 90:4536-4541, 2005 

2004

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Brown LB, Streeten EA, Shuldiner AR, Almasy LA, Peyser PA, Mitchell BD. Assessment of sex-specific genetic and environmental effects on bone mineral density.  Genetic Epid 27:153-161, 2004

Damcott C, Hoppman N, Reinhart LJ, Wang J, O'Connell JR, Mitchell BD, Shuldiner AR.  Polymorphisms in both promoters of hepatocyte nuclear factor 4-alpha are associated with type 2 diabetes in the Amish.  Diabetes 53:3337-3341, 2004.  

Fu M, Damcott C, Sabra M, Pollin TI, Ott S, Wang J, Garant M, O'Connell J, Mitchell BD, Shuldiner AR.  Polymorphism in the Calsequestrin 1 gene on chromosome 1q21 is associated with type 2 diabetes in the Old Order Amish.   Diabetes 53:3292-3299, 2004.

Pollin TI, Hsueh W-C, Steinle NI, Snitker S, Shuldiner AR, Mitchell BD.  A genome-wide scan of lipid levels in the Old Order Amish.   Atherosclerosis 173:89-96, 2004 (pdf);  (Supplemental Data).

Snitker S., Shuldiner A.R. BMI in the Old Order Amish (letter) Med Sci Sports Exerc 36, 1447, 2004.

Streeten EA, McBride DJ, Lodge A, Pollin T, Stinchcomb DG, Agarwala R, Schäffer AA, Shapiro JR, Shuldiner AR, Mitchell BD.  Reduced Incidence of Hip Fracture in the Old Order Amish.   J Bone Miner Res 19:308-313, 2004 .

Steinle NI, Kazlauskaite R, Imumorin IG, Hsueh W-C, Pollin TI, Mitchell BD, Shuldiner AR.  Variation in the lamin A/C (LMNA) gene: Associations with metabolic syndrome.  Arterio Thromb Vasc Biol 24:1708-13, 2004.

2003

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Allen EM, Hsueh W-C, Sabra MM, Pollin TI, Ladenson PW, Silver KD, Mitchell BD, Shuldiner AR.  A genome-wide scan for autoimmune thyroiditis in the Old Order Amish: Replication of genetic linkage on chromosome 5q11.2-q14.3. J Clin Endocrinol Metab 88:1292-1296, 2003.

Hsueh W-C, St. Jean PL, Mitchell BD, Pollin TI, Knowler WC, Ehm MG, Bell CJ, Sakul H, Wagner MJ, Burns DK, Shuldiner AR.  Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: Evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24.   Diabetes 52:550-557,  2003.

Miura J, Pollin T, Hu Y, Notkins AL, Shuldiner AR.  Autoantibodies in type 2 and type 2 diabetes in the Old Order Amish of Pennsylvania  Diabetologia 46, 1024-1025, 2003. 

Snitker S, Mitchell BD, Shuldiner AR.  Physical activity and prevention of type 2 diabetes (letter).  Lancet 361:87-88, 2003.

2000 thru 2002

Hsueh W-C, Mitchell BD, Aburomia R, Sakul H, Ehm MG, Michelsen B, Wagner MJ, St. Jean PL, Knowler WC, Burns DK, Bell CJ, Shuldiner AR.  Diabetes in the Old Order Amish: characterization and heritability analysis of the Amish Family Diabetes Study.  Diab Care 23:595-601, 2000.  

Hsueh W-C, Mitchell BD, Schneider JL, Wagner M, Bell CJ, Nanthakamur E, Shuldiner AR.  A QTL influencing blood pressure maps to the region of PPH1 on chromosome 2q31-34 in the Old Order Amish.  Circulation 101:2810-2816, 2000.

Hsueh W-C, Mitchell BD, Schneider JL, St. Jean PL, Pollin TI, Ehm MG, Wagner MJ, Burns DK, Bell CJ, Shuldiner AR.  Genome-wide scan of obesity and leptin levels in the Old Order Amish. J Clin Endocrinol Metab 86:1199-1205, 2001.

Mitchell BD, Hsueh W-C, King TM, Pollin TI, Sorkin J, Agarwala R, Schaffer AA, Shuldiner AR.  Heritability of life span in the Old Order Amish.  Am J Med Genet 102:346-352, 2001.
   
Steinle N, Hsueh W-C, Snitker S, St. Jean PL, Sakul H, Ehm MG, Burns DK, Bell CJ, Mitchell BD, Shuldiner AR.  Eating behavior in the Old Order Amish: heritability analysis and a genome wide scan.  Am J Clin Nutr 75:1098-1106, 2002. 

Steinle N, Shuldiner AR. The Old Order Amish: A unique model to study aging.  J Brit Menop Soc 6, 127-128, 2000.

 

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