Heredity & Phenotype Interaction (Heart) Study (HAPI)
Principal Investigator: Dr. Alan Shuldiner
This study was designed to better understand how genes interact with common lifestyle factors like stress and diet to contribute to heart disease. It was very successful – nearly 900 Amish volunteered for this study. Although we are not recruiting any new volunteers, we are working very hard in the laboratory in Baltimore to analyze all of the information we have collected. We have already discovered a number of gene variants that influence heart disease and other medically relevant traits such as cholesterol and glucose levels.