The Division of Endocrinology, Diabetes and Nutrition has enjoyed unprecedented growth to become one of the largest and successful Divisions’ of Endocrinology in the country. Guided by its mission of excellence in research and discovery, clinical care, and education, we have made great strides in each of these arenas. All but three of the 22 full-time faculty have been recruited by Dr. Alan Shuldiner since his arrival at the University of Maryland in 1997. There are four professors, four associate professors, 12 Assistant Professors, and two instructors or research associates. The faculty are extraordinarily collegial and collaborative and have diverse interests spanning clinical endocrinology/diabetes, clinical research/trials, epidemiology, cellular and molecular biology, functional genomics, and molecular and statistical genetics.
Future challenges include continued growth of the research program, ongoing improvement of current clinical programs, and the development of new programs (bariatrics, in-patient diabetes management) to meet the current and future needs of patients with endocrine disorders and diabetes.
Facilities and Resources
All of the Division’s faculty members have private offices distributed in the research area (Howard Hall 4 and 5), clinical Endocrinology offices (UMMC 3rd floor), or Baltimore, VA Medical Center. Research resources include approximately 7,000 square feet of state-of-the-art wet lab space fully equipped to perform molecular, cellular, functional genomics and high-throughput genetics research (Howard Hall 4 and 5); over 1,500 square feet of office space with networked Unix and PC computer hardware for the Genetic Epidemiology Unit led by Dr. Braxton Mitchell (Howard 4 and 5 and MSTF 3); and approximately 500 square feet of clinical research space at the Joslin Diabetes Center (UMMC 6).
The Division’s Clinical Research Unit is equipped to perform investigator-initiated clinical research and therapeutic trials for diabetes, diabetic complications and obesity; procedures and measurements we perform include anthropometry, body composition, energy expenditure, insulin sensitivity/insulin secretion (clamps), microdialysis, microneurography, and muscle and fat biopsies.
The Nutrition Obesity Research Center (NORC) of Maryland is a center funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in 2005. The mission of the NORC of Maryland is to foster multidisciplinary research approaches to understanding the impact of nutrition on risk for chronic disease and translate this knowledge into effective clinical treatments and prevention efforts.
Investigators from University of Maryland and the Johns Hopkins University have also joined together to create the Baltimore Diabetes Research and Training Center (DRTC). The Center fosters collaborative, multidisciplinary diabetes and endocrinology research, and translates that research into programs to train health care professionals in the diagnosis and management of diabetes.
Core resources for the NIH Nutrition Obesity Research Center (NORC) of Maryland and the Baltimore Diabetes Research and Training Center (DRTC) are housed in the EDN Division's research space. Resources from these NIH-funded Centers are accessible to its members at the University of Maryland, Johns Hopkins University, and the United States Department of Agriculture (USDA).
The Amish Research Clinic is located in Strasburg, PA. Staffed by 10 full-time employees, this 1,500 square foot clinical research facility performs field-work, recruitment, and phenotypic characterization of Amish research volunteers for more than 10 concurrent studies.
The Hypertension and Endocrine Research Unit (HEU), directed by Drs. Bruce and Jennifer Hamilton, is a large clinical research facility at the Baltimore VAMC. This 1500 square foot facility is equipped with examination rooms, clinical lab, procedure rooms and data storage. Multiple clinical research studies have been performed in the fields of hypertension, dyslipidemia, and diabetes both single and multiple site, including the ALLHAT Study and the ongoing ACCORD Study. Finally, several of the Division’s clinical investigators utilize the University of Maryland General Clinical Research Center for some of their more intensive NIH-funded protocols.