| CVID NEWS - 2008 | |
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| Toni M. Antalis, PhD, professor, Department of Physiology and Center for Vascular and Inflammatory Diseases, has been elected chair of the Publications Committee of the American Society for Biochemistry and Molecular Biology. |  |
| Leonid Medved, PhD, professor, Department of Biochemistry & Molecular Biology and the Center for Vascular and Inflammatory Diseases, received a four-year $1.5 million R01 grant from the National Heart, Lung and Blood Institute for his work entitled “Fibrin(ogen) Structure and Interactions.”
Dr. Medved as an invited speaker at the 54th Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis in Vienna, Austria, in July 2008. His presentation was entitled “Nomenclature of Fibrinogen and Fibrin.” Additionally, in July 2008, Dr. Medved was an invited speaker at the XIXth International Congress of the International Society for Fibrinolysis and Proteolysis in Vienna, Austria, presenting “Evidence for B-hairpin Swapping as a Possible Mechanism of αC-polymer For-mation in Fibrin” and then presented “Molecular Mechanism of αC-polymer Formation by Fibrin αC-domains” at the XXth International Fibrinogen Workshop in Venice, Italy. |
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David Scott Ph.D., professor, Departments of Surgery and Microbiology and Immunology and Center for Vascular and Inflammatory Diseases has been awarded three grants for his work on immune tolerance induction.
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Jeffrey Winkles Ph.D. published an invited review article titled "The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting" in the journal Nature Reviews.
TWEAK is a multifunctional cytokine that controls many cellular activities including proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK acts by binding to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-B) pathway. Dr. Winkles received a three-year $600,000 grant from Susan G. Komen for the Cure for his work entitled “Role of the Fn14/NF-kB Signaling Pathway in HER2-Positive Breast Cancer.” |
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| CVID Investigators Receive Stem Cell Funding | |
| Sarah Netzel-Arnett, Ph.D. from the Department of Physiology and the Center for Vascular and Inflammatory Diseases received a two-year $230,000 grant from the Maryland Stem Cell Fund for her work entitled "Targeting Prosurvival Pathways for Enhanced Stem Cell Based Therapy."
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| American Heart Association Poster Awards | |
| Marguerite Buzza, Ph.D., a CJ Martin Postdoctoral Research Fellow and Ian Anglin, Ph.D., a Senior Postdoctoral Research Fellow from the Center for Vascular and Inflammatory Diseases, each received competitive 2008 American Heart Association Poster Awards at the Gordon Conference on Plasminogen Activation and Extracellular Proteolysis in Ventura, CA. Dr Buzza'a poster was entitled "Matriptase regulates barrier formation in intestinal epithelial cells". Dr Anglin's poster was entitled "Intracellular Plasminogen Activator Inhibitor Type 2 (SerpinB2) modulates calpain activity". | |
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