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Publications - Escherichia Coli

Levine MM, Rennels MB, Cisneros L, Hughes TP, Nalin DR, Young CR. Lack of person-to-person transmission of enterotoxigenic Escherichia coli despite intimate contact. Am. J. Epidemiol. 1980;111:347-355.

Levine MM, Rennels MB, Daya V, Hughes TP. Hemagglutination and colonization factors in enterotoxigenic and enteropathogenic Escherichia coli that cause diarrhea. J. Infect. Dis. 1980;141:733-737.

Clements ML, Levine MM, Black RE, Robins-Browne RM, Cisneros LA, Drusano GL, Lanata CF, Saah AJ. Lactobacillus prophylaxis for diarrhea due to enterotoxigenic Escherichia coli. Antimicrob. Ag. Chemother. 1980;20:104-108.

Robins-Browne R, Levine MM. Effect of chlorpromazine on intestinal secretion mediated by Escherichia coli heat-stable enterotoxin and 8-Br-Cyclic GMP in mice. Gastroenterology. 1981;80:321-326.

Candy DCA, Leuang TSM, Mak RHK, Harries JT, Marshall WC, Phillips AD, Robins-Browne R, Chadwick MV, Levine MM. A fimbrial antigen mediating adhesion and hemagglutination of Escherichia coli from children. FEMS Microbiol. Lett. 1982;15:325-329.

Levine MM, Black RE, Brinton CC Jr, Clements ML, Fusco P, Hughes TP, O'Donnell S, Robins-Browne R, Wood S, Young CR. Reactogenicity, immunogenicity and efficacy studies of Escherichia coli type 1 somatic pill parenteral vaccine in man. Scand. J. Infect. Dis. Supplement 1982;33:83-95.

Black RE, Levine MM, Clements ML, Cisneros L, Daya V. Treatment of experimentally induced enterotoxigenic Escherichia coli diarrhea with trimethoprim, trimethoprim/sulfamethoxazole, or placebo. Rev. Infect. Dis. 1982;4:550-545.

Robins-Browne RM, Levine MM, Rowe B, Gabriel EM. Failure to detect conventional enterotoxin in classical enteropathogenic (serotyped) Escherichia coli strains of proven pathogenicity. Infect. Immun. 1982;38:798-801.

Levine MM, Ristaino P, Sack RB, Kaper JB, Orskov F, Orskov I. Colonization factor antigens I and II and type 1 somatic pili in enterotoxigenic Escherichia coli: relation to enterotoxin type. Infect. Immun. 1983;39:889-897.

Baldini MM, Kaper JB, Levine MM, Candy DCA, Moon HW. Plasmid mediated adhesion in enteropathogenic Escherichia coli. J. Ped. Gastroenterol. 1983;2:534-538.

Levine MM. Traveller's Diarrhoea: Prospects for successful immunoprophylaxis. Scand. J. Gastroenterol. Vol. 18 supplement 1983;84:121-134.

Ristaino P, Levine MM, Young CR. An improved GM1-enzyme-linked immunosorbent assay for the detection of Escherichia coli heat-labile enterotoxin. J. Clin. Microbiol. 1983;18:808-815.

Moon HW, Whipp SC, Argenzio RA, Levine MM, Gianella RA. Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines. Infect. Immun. 1983;41:1340-1351.

Edelman RE, Levine MM. Summary of a workshop on enteropathogenic Escherichia coli. J. Infect. Dis. 1983;147:1108-1118.

Levine MM, Edelman R. Enteropathogenic Escherichia coli of classical serotypes associated with infant diarrhea - epidemiology and pathogenesis. Epidemiol. Rev. 1984;6:31-51.

Levine MM, Ristaino P, Marley G, Smyth C, Knutton S, Boedeker E, Black R, Young C, Clements ML, Cheney C, Patnaik R. Coli surface antigens 1 and 3 of colonization factor antigen II-positive enterotoxigenic Escherichia coli: morphology, purification, and immune responses in humans. Infect. Immun. 1984;44:409-420.

Nataro JP, Scaletsky ICA, Kaper JB, Levine MM, Trabulsi LR. Plasmid-mediated factors conferring diffuse and localized adherence of enteropathogenic Escherichia coli. Infect. Immun. 1985;48:378-383.

Nataro JP, Baldini MM, Kaper JB, Black RE, Levine MM. Detection of an adherence factor of enteropathogenic Escherichia coli with a DNA probe. J. Infect. Dis. 1985;152:560-565.

Levine MM, Nataro JP, Baldini MM, Kaper JB, Black RE, Clements ML, O'Brien AD. The diarrheal response of humans to some classical serotype enteropathogenic Escherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor. J. Infect. Dis. 1985;152:550-559.

Lanata CF, Kaper JB, Baldini MM, Black RE, Levine MM. Sensitivity and specificity of DNA probes for the detection of E. coli enterotoxins using the stool blot techniques. J. Infect. Dis. 1985;152:1087-1090.

Levine MM. Escherichia coli infections. N. Eng. J. Med. 1985;313:445-447.

Baldini MM, Nataro JP, Kaper JB. Localization of a determinant for HEp-2 adherence by enteropathogenic Escherichia coli. Infect. Immun. 1986;52:334-336.

Thompson MR, Jordan RL, Luttrell MA, Brandwein H, Kaper JB, Levine MM, Gianella RA. A blinded two laboratory comparative analysis of E. coli STa production using monoclonal antibody ELISA, radioimmunoassay, suckling mouse assay and gene probe analysis. J. Clin. Microbiol. 1986;24:753-758.

Echeverria P, Taylor DN, Donohue-Rolfe A, Supawat K, Ratchtrachenchai O, Kaper JB, Keusch GT. HeLa cell adherence and cytotoxin production by enteropathogenic Escherichia coli isolated from infants with diarrhea in Thailand. J. Clin. Microbiol. 1987;25:1519-1523.

Chatkaeomorakot A, Echeverria P, Taylor DN, Bettelheim KA, Blacklow NR, Sethabutr O, Seriwatana J, Kaper JB. HeLa cell-adherent Escherichia coli in children with diarrhea in Thailand. J. Infect. Dis., 1987;156:669-672.

Karch H, Heeseman J, Laufs R, O'Brien AD, Tacket CO, Levine MM. A plasmid of enterohemorrhagic Escherichia coli 0157:H7 is required for expression of a new fimbrial antigen and for adhesion to epithelial cells. Infect. Immun. 1987;55:455-461.

Karch H, Heesemann J, Laufs R, Kroll HP, Kaper JB, Levine MM. Serological response to type 1-like somatic fimbriae in diarrheal infection due to classical enteropathogenic Escherichia coli. Microbial Pathogenesis, 1987;2:425-434.

Levine MM. Escherichia coli that cause diarrhea: enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic and enteroadherent. J. Infect. Dis. 1987;155:377-389.

Levine MM, Xu J-G, Kaper JB, Lior H, Prado V, Tall B, Nataro J, Karch H, Wachsmuth IK. A DNA probe to identify enterohemorrhagic Escherichia coli 0157:H7 and other serotypes that cause hemorrhagic colitis and hemolytic uremic syndrome. J. Infect. Dis. 1987;156:175-182.

Gomes TAT, Toledo MRF, Trabulsi LR, Wood PK, Morris JG. Use of DNA probes in the identification of enteroinvasive Escherichia coli. J. Clin. Microbiol. 1987;25:2025-27.

Tacket CO, Maneval DR, Levine MM, A new fimbrial putative colonization factor of enterotoxigenic Escherichia coli 0159:H4: purification, morphology, and genetics. Infect. Immun. 1987;55:1063-1069.

Black RE, Levine MM, Clements ML, Hughes T, O'Donnell S. Association between 0 blood group and occurrence and severity of diarrhoea due to Escherichia coli. Trans. Royal Soc. Trop. Med. Hyg. 1987;81:120-123.

Knutton S, Baldini MM, Kaper JB, McNeish AS. Role of plasmid-encoded adherence factors in adhesion of enteropathogenic Escherichia coli to HEp-2 cells. Infection and Immunity, 1987;55:78-85.

Nataro JP, Maher KO, Mackie P, Kaper JB. Characterization of plasmids encoding the adherence factor of enteropathogenic Escherichia coli. Infection and Immunity, 1987;55:2370-2377.

Nataro JP, Kaper JB, Robins-Browne R, Prado V, Vial PA, Levine MM. Patterns of adherence of diarrheagenic Escherichia coli to HEp-2 cells. Pediat. Infect. Dis. J. 1987;6:829-831.

Tzipori S, Karch H, Wachsmuth KI, Robins-Browne RM, O'Brien AD, Lior H, Cohen ML, Smithers J, Levine MM. Role of a 60-megadalton plasmid and Shiga-Like toxins in the pathogenesis of infection caused by enterohemorrhagic Escherichia coli 0157:H7 in gnotobiotic piglets. Infect. Imm. 1987;55:3117-3125.

Tacket CO, Losonsky G, Link H, Hoang Y, Guesry P, Hilpert H, Levine MM, Protective efficacy of a milk immunoglobulin concentrate against oral challenge with enterotoxigenic Escherichia coli. New England J. Med. 1988;318:1240-1243.

Levine MM, Prado V, Robins-Browne R, Lior H, Kaper JB, Moseley SL, Gicquelais K, Nataro JP, Vial P, Tall B. DNA probes and HEp-2 cell adherence assay to detect diarrheagenic Escherichia coli. J. Infect. Dis. 1988;158:224-228.

Vial P, Robins-Browne R, Lior H, Prado V, Nataro J, Kaper J, Elsayed A, Maneval D, Levine MM. Characterization of enteroadherent-aggregative Escherichia coli: a newly-defined agent of diarrheal disease. J. Infect. Dis. 1988;158:70-79.

Levine MM, Vial PA. Escherichia coli that cause diarrhea. Indian J. Pediat. 1988;55:183-190.

Bhan MK, Raj P, Levine MM, Kaper JB, Bhandari N, Srivastava R, Kumar R, Sazawal S. Enteroaggregative Escherichia coli associated with persistent diarrhea in a cohort of rural children in India. J. Infect. Dis. 1989;159:1061-1064.

Hall RH, Maneval DR, Collins JH, Theibert JL, Levine MM. Purification and analysis of colonization factor antigen I, coli surface antigen 1, and coli surface antigen 3 fimbriae from enterotoxigenic Escherichia coli. J. Bacteriol. 171:6372-6374.

Wood, PK, Morris, JG, Small, PLC, Sethabutr, O, Trabulsi, L, Kaper, JB, Comparison of DNA probes with the Sereny test in the identification of invasive strains of shigella and Escherichia coli. J. Clin. Microbiol., 1986;24:498-500.

Baudry B, Savarino SJ, Vial PA, Kaper JB, Levine MM. A sensitive and specific DNA probe to identify enteroaggregative Escherichia coli, a recently-discovered diarrheal pathogen. J. Infect. Dis. 1990;161:1249-1251.

Caron J, Maneval DR, Kaper JB, Scott JR. Association of Rns homologs with CFA antigen in clinical Escherichia coli isolates. Infect. Immun. 1990;58:3442-3444.

Clemens JD, Svennerholm AM, Harris JR, Huda S, Rao M, Neogy PK, Khan MR, Ansaruzzaman M, Rahaman S, Ahmed F. Seroepidemiologic evaluation of anti-toxic and anti-colonization factor immunity against infections by LT-producing Escherichia coli in rural Bangladesh. J. Infect. Dis. 1990;162:448-453.

Donnenberg MS, Calderwood SB, Donohue-Rolfe A, Keusch GT, Kaper JB. Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells. Infect. Immun. 1990;58:1565-1571.

Fasano A, Kay BA, Russell RG, Maneval DR, Levine MM. Enterotoxin and cytotoxin production by enteroinvasive Escherichia coli. Infect. Immun. 1990;58:3717-3723.

Gicquelais KG, Baldini MM, Martinez J, Maggi L, Martin WC, Prado V, Kaper JB, Levine MM. Practical and economical method for using biotinylated DNA probes with bacterial colony blots to identify diarrhea-causing Escherichia coli. J. Clin. Microbiol. 1990;28:2485-2490.

Jerse AE, Martin WC, Galen JE, Kaper JB. An oligonucleotide probe for the detection of the EPEC adherence factor EAF of localized adherent enteropathogenic Escherichia coli. J. Clin. Microbiol. 1990;28:2842-2844.

Jerse AE, Yu J, Tall BD, Kaper JB. A genetic locus of enteropathogenic Escherichia coli necessary for production of attaching and effacing lesions on tissue culture cells. Proc. Nat. Acad. Sci., USA 1990;87:7839-7843.

Tacket CO, Moseley SL, Kay B, Losonsky G, Levine MM. Challenge studies in volunteers using Escherichia coli strains with diffuse adherence to HEp-2 cells. J. Infect. Dis. 1990;162:550-552.

Francis DL, Jerse AE, Kaper JB, Falkow S. Characterization of interactions of enteropathogenic Escherichia coli O127:H6 with mammalian cells in vitro. J. Infect. Dis. 1991;164:693-703.

Jerse AE, Gicquelais KG, Kaper JB. Plasmid and chromosomal elements involved in the pathogenesis of attaching and effacing Escherichia coli. Infection and Immunity 1991;59:3869-3875.

Jerse AE, Kaper JB. The eae gene of enteropathogenic Escherichia coli encodes a 94 kDa membrane protein, the expression of which is influenced by the EAF plasmid. Infection and Immunity 1991;59:4302-4309.

Giron JA, Jones T, Millan-Velasco F, Munoz-Castro E, Fry J, Frankel G, Moseley SL, Baudry B, Kaper JB, Schoolnik GK, Riley LW. Diffuse-adhering Escherichia coli (DAEC) as a putative cause of diarrhea in Mayan children in Mexico. J. Infect. Dis. 1991;163:507-513.

Savarino SJ, Fasano A, Robertson DC, Levine MM. Enteroaggregative Escherichia coli elaborate a heat-stable enterotoxin demonstrable in an in vitro rabbit intestinal model. J. Clin. Investig. 1991;87:1450-1455.

Barrett TJ, Kaper JB, Jerse AE, Wachsmuth IK. Virulence factors in shiga-like toxin producing Escherichia coli isolated from humans and cattle. J. Infect. Dis. 1992;165:979-980.

Cordovez A, Prado V, Maggi L, Cordero J, Martinez J, Misraji A, Rios R, Soza G, Ojeda A, Levine MM. Enterohemorrhagic Escherichia coli associated with hemolytic-uremic syndrome in Chilean children. J Clin Microbiol 1992;30:2153-2157.

Donnenberg M., Giron J., Nataro J., Kaper J. A Plasmid-Encoded Type IV Fimbrial Gene of Escherichia coli Associated with Localized Adherence. Molec Microbiol 6: 3427-3437, 1992.

Echeverria P, Serichantalerg O, Changchawalit S, Baudry B, Levine MM, Orskov F, Orskov I. Tissue culture-adherent Escherichia coli in infantile diarrhea. J. Infect. Dis. 1992;165:141-143.

Nataro JP, Deng Y, Maneval DR, German AL, Martin WC, Levine MM. Aggregative adherence fimbriae I of enteroaggregative Escherichia coli mediate adherence to HEp-2 cells and hemagglutination of human erythrocytes. Infect Immun 1992;60:2297-2304.

Tzipori S, Montanaro J, Robins-Browne RM, Vial P, Gibson R, Levine MM. Studies with enteroaggregative Escherichia coli in the gnotobiotic piglet gastroenteritis model. Infect Immun 1992;60:5302-5306.

Yu J, Kaper JB. Cloning and characterization of the eae gene of enterohaemorrhagic Escherichia coli 0157:H7. Molec Microbiol 1992;6:411-417.

Weintraub A, Leontein K, Widmalm G, Vial PA, Levine MM, Lindberg AA. Structural studies of the O-antigenic polysaccharide of an enteroaggregative Escherichia coli strain. Euro J Biochem 213:859-864, 1993.

Wolf MK, Taylor DN, Boedeker EC, Hyams KC, Maneval DR, Levine MM, Tamura K, Wilson RA, Echeverria P. Characterization of enterotoxigenic Escherichia coli isolated from US troops deployed to the Middle East. J Clin Microbiol 31:851-856, 1993.

Nataro, JP, Yikang, D, Giron, J, Savarino, SJ, Kothary, MH, Hall, R. Aggregative Adherence Fimbriae I expression in enteroaggregative Escherichia coli requires two unlinked plasmid regions. Infection and Immunity 61:1126-1131, 1993.

Savarino SJ, Fasano A, Watson J, Martin BM, Levine MM, Guandalini S, Guerry P. Enteroaggregative Escherichia coli heat-stable enterotoxin 1 represents another subfamily of E. coli heat-stable toxin. PNAS 90:3093-3097, 1993.

Levine MM, Ferreccio C, Prado V, Cayazzo M, Abrego P, Martinez J, Maggi L, Baldini MM, Martin W, Maneval D, Kay B, Guers L, Lior H, Wasserman SS, Nataro JP. Epidemiologic studies of Escherichia coli diarrheal infections in a low socioeconomic level peri-urban community in Santiago, Chile. American Journal of Epidemiology, 1993, 138:849-869.

Donnenberg, M.S., S. Tzipori, M.L. McKee, A.D. O'Brien, J. Alroy, and J.B. Kaper. The Role of the eae Gene of Enterohemorrhagic Escherichia coli in Intimate Attachment in Vitro and in a Porcine Model. Journal of Clinical Investigation. 1993, 92:1418-1424.

Donnenberg, M.S., J. Yu, and J.B. Kaper. A Second Chromosomal Gene Necessary for Intimate Attachment of Enteropathogenic Escherichia coli to Epithelial Cells. Journal of Bacteriology. 1993, 175:4670-4680.

Edelman R, Russell RG, Losonsky G, Tall BD, Tacket CO, Levine MM, Lewis DH. Immunization of rabbits with enterotoxigenic E. coli colonization factor antigen (CFA/I) encapsulated in biodegradable microspheres of poly (lactide-co-glycolide). Vaccine 11:155-158, 1993.

Donnenberg MS, Tacket CO, James S, Losonsky G, Nataro JP, Wasserman S, Kaper JB, Levine MM. The role of the eaeA gene in experimental enteropathogenic Escherichia coli infection. J Clin Invest, 1993, 92, 1412-1417.

Girón, J.A., M.S. Donnenberg, W.C. Martin, K.G. Jarvis, and J.B. Kaper. Distribution of the Bundle-Forming Pilus Structural Gene (bfpA) among Enteropathogenic Escherichia coli. Journal of Infectious Diseases.1993, 168:1037-1041.

Canil, C., I. Rosenshine, S. Ruschkowski, M.S. Donnenberg, J.B. Kaper, and B.B. Finlay. Enteropathogenic Escherichia coli Decreases the Transepithelial Electrical Resistance of Polarized Epithelial Monolayers. Infection and Immunity. 1993, 61:2755-2762.

Cohen MB, Hawkins JA, Weckbach LS, Staneck JL, Levine MM, Heck JE. Colonization by enteroaggregative Escherichia coli in travelers with and without diarrhea. J Clin Microbiol 31:351-353, 1993.

Girón, J.A., M.M. Levine, and J.B. Kaper. Longus: a long pilus ultrastructure produced by human enterotoxigenic Escherichia coli. Molecular Microbiology. 1994, 12:71-82.

Medina EC, Widmalm G, Weintraub PA, Levine MM, Lindberg AA. Structural studies of the O-antigenic polysaccharides of Escherichia coli O3 and the enteroaggregative Escherichia coli strain 17-2. Eur J Biochem 224:191-196, 1994.

Nataro, JP, Deng, Y, Deng, Y, Walker, K. AggR, a transcriptional activator of Aggregative Adherence Factor I expression. Journal of Bacteriology 176:4691-4699, 1994.

Savarino, SJ, Fox, P, Deng, Y, Nataro, JP. Identification and characterization of a gene cluster mediating enteroaggregative Escherichia coli aggregative adherence fimbria I biogenesis. Journal of Bacteriology. 176(16):4949-57, 1994.

Scott, D.A. and J.B. Kaper. Cloning and Sequencing of Genes Encoding Cytolethal Distending Toxin of Escherichia coli. Infection and Immunity. 1994, 62:244-251.

Tacket CO, Reid RH, Boedeker EC, Losonsky GA, Nataro JP, Bhagat H, Edelman R. Enteral immunization and challenge of volunteers given enterotoxigenic E. coli CFA/II encapsulated in biodegradable microspheres. Vaccine 12:1270-1274, 1994.

Tzipori, S., F. Gunzer, M.S. Donnenberg, L. DeMontigny, J.B. Kaper, and A. Donogue-Rolfe. The role of the eaeA gene in diarrhea and neurological complications in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection. Infection and Immunity, 1995, 63:3621-3627.

Girón, JA, GI Viboud, V Sperandio, AG Gómez-Duarte, DR Maneval, MJ Albert, MM Levine JB Kaper. Prevalence and association of the longus pilus structural gene (IngA) with colonization factor antigens, enterotoxin types, and serotypes of enterotoxigenic Escherichia coli. Infection and Immunity, 1995, 63:4195-4198.

Girón, JA, J-G Xu, CR Gonzalez, D Hone, JB Kaper, MM Levine. Simultaneous and constitutive expression of CFA/I and CS3 colonization factors of enterotoxigenic Escherichia coli by ªaroC, ªaroD Salmonella typhi vaccine strain CVD 908. Vaccine, 1995, 13:939-946.

Gomez, O.G. and J.B. Kaper. A Plasmid-encoded regulatory region activates chromosomal eaeA expression in enteropathogenic Escherichia coli. Infection and Immunity, 1995, 63:1767-1776.

Jarvis, K. G., J. A. Girón, A. E. Jerse, T. K. McDaniel, M. S. Donnenberg, and J. B. Kaper. Enteropathogenic Escherichia coli contains a specialized secretion system necessary for the export of proteins involved in attaching and effacing lesion formation. Proceedings of the National Academy Science USA, 1995, 92:7996-8000.

Nataro JP, Seriwatana J, Fasano A, Maneval DR, Guers LD, Noriega F, Dubovsky F, Levine MM, Morris JG Jr. Identification and cloning of a novel plasmid-encoded enterotoxin in enteroinvasive Escherichia coli and Shigella. Infect Immun, 63:4721-4728, 1995

Nataro JP, Yikang D, Cookson S, Cravioto A, Savarino SJ, Guers LD, Levine MM, Tacket CO. Heterogeneity of enteroaggregative E. coli virulence demonstrated in volunteers. Journal of Infectious Diseases 171:465-468, 1995.

Nataro JP, Savarino SJ, Yikang D, Cookson S, Cravioto A, Guers LD, Levine MM, Tacket CO. Heterogeneity of enteroaggregative Escherichia coli virulence demonstrated in volunteers. Journal of Infectious Diseases, 1995, 171, 465-468.

Ojeda A, Prado V, Martinez J, Arellano C, Borczyk A, Johnson W, Lior H, Levine MM. Sorbitol-negative phenotype among enterohemorrhagic Escherichia coli of different serotypes and sources. J Clin Microbiol, 33:2199-2201, 1995.

M, Rivas M, Levine MM. Escherichia coli enterohemorrhágica en el sindrome hemolítica urémico, en niños chilenos. Rev Med Chile 123:13-22, 1995.

Agin TS, Cantey JR, Boedeker EC, Wolf MK. Characterization of the eaeA gene from rabbit enteropathogenic Escherichia coli strain RDEC-1 and comparison to other eaeA genes from bacteria that cause attaching-effacing lesions. FEMS Microbiol. Lett. 1996;144:249-258.

Albert MJ, Faruque SM, Faruque AS, Bettelheim KA, Neogi PK, Bhuiyan NA, Kaper JB. Controlled study of cytolethal distending toxin-producing Escherichia coli infections in Bangladeshi children. J. Clin. Microbiol. 1996;34:717-719.

Cookson ST, Nataro JP. Characterization of HEp-2 cell projection formation induced by diffusely adherent Escherichia coli. Microb Pathog 1996;21:421-434.

Jarvis KG, Kaper JB. Secretion of extracellular proteins by enterohemorrhagic Escherichia coli via a putative type III secretion system. Infect. Immun. 1996;64:4826-4829.

Nataro JP, Hicks S, Phillips AD, Vial PA, Sears CL. T84 cells in culture as a model for enteroaggregative Escherichia coli pathogenesis. Infect. Immun. 1996;64:4761-4768.

Panigrahi P, Bamford P, Horvath K, Morris JG Jr, Gewolb IH. Escherichia coli transcytosis in a Caco-2 cell model: implications in neonatal necrotizing enterocolitis. Pediatr. Res. 1996;40:415-421.

Rabinowitz RP, Lai LC, Jarvis K, McDaniel TK, Kaper JB, Stone KD, Donnenberg MS. Attaching and effacing of host cells by enteropathogenic Escherichia coli in the absence of detectable tyrosine kinase mediated signal transduction. Microb. Pathog. 1996;21:157-171.

Savarino SJ, McVeigh A, Watson J, Cravioto A, Molina J, Echeverria P, Bhan MK, Levine MM, Fasano A. Enteroaggregative Escherichia coli heat-stable enterotoxin is not restricted to enteroaggregative E. coli. J. Infect. Dis. 1996;173:1019-1022.

Tilden J. Jr, Young W, McNamara AM, Custer C, Boesel B, Lambert-Fair MA, Majkowski J, Vugia D, Werner SB, Hollingsworth J, Morris JG Jr. A new route of transmission for Escherichia coli: infection from dry fermented salami. Am. J. Public Health 1996;86:1142-1145.

Czeczulin JR, Balepur S, Hicks S, Phillips A, Hall R, Kothary MH, Navarro-Garcia F, Nataro JP. Aggregative adherence fimbria II, a second fimbrial antigen mediating aggregative adherence in enteroaggregative Escherichia coli. Infect. Immun. 1997;65:4135-45.

Donnenberg MS, Kaper JB, Finlay BB. Interactions between enteropathogenic Escherichia coli and host epithelial cells. Trends Microbiol. 1997;5:109-114.

Elliott SJ, Kaper JB. Role of type 1 fimbriae in EPEC infections. Microb. Pathog. 1997;23:113-118.

Hedberg CW, Savarino SJ, Besser JM, Paulus CJ, Thelen VM, Myers LJ, Cameron DN, Barrett TJ, Kaper JB, Osterholm MT. An outbreak of foodborne illness caused by Escherichia coli O39:NM, an agent not fitting into the existing scheme for classifying diarrheagenic E. coli. J. Infect. Dis. 1997;176:1625-1628.

Kaper JB, Gomez-Duarte OG. The per regulator of enteropathogenic Escherichia coli. [LETTER]. Mol. Microbiol. 1997;23:179-181.

Kaper JB, McDaniel TK, Jarvis KG, Gomez-Duarte O. Genetics of virulence of enteropathogenic E. coli. Adv. Exp. Med. Biol. 1997;412:279-287.

Karaolis DK, McDaniel TK, Kaper JB, Boedeker EC. Cloning of the RDEC-1 locus of enterocyte effacement (LEE) and functional analysis of the phenotype on HEp-2 cells. Adv. Exp. Med. Biol. 1997;412:241-245.

McDaniel TK, Kaper JB. A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12. Mol. Microbiol. 1997;23:399-407.

Mynott TL, Guandalini S, Raimondi F, Fasano A. Bromelain prevents secretion caused by Vibrio cholerae and Escherichia coli enterotoxins in rabbit ileum in vitro. Gastroenterology 1997;113:175-184.

Noel JM, Boedeker EC. Enterohemorrhagic Escherichia coli: a family of emerging pathogens. Dig Dis. 1997;15:67-91.

Polotsky Y, Nataro JP, Kotler D, Barrett TJ, Orenstein JM. HEp-2 cell adherence patterns, serotyping, and DNA analysis of Escherichia coli isolates from eight patients with AIDS and chronic diarrhea. J. Clin. Microbiol. 1997;35:1952-1958.

Wieler LH, McDaniel TK, WhittAm. TS, Kaper JB. Insertion site of the locus of enterocyte effacement in enteropathogenic and enterohemorrhagic Escherichia coli differs in relation to the clonal phylogeny of the strains. FEMS Microbiol. Lett. 1997;156:49-53.

Wolf MK, de Haan LA, Cassels FJ, Willshaw GA, Warren R, Boedeker EC, Gaastra W. The CS6 colonization factor of human enterotoxigenic Escherichia coli contains two heterologous major subunits. FEMS Microbiol. Lett. 1997;148:35-42.

Collington GK, Booth IW, Donnenberg MS, Kaper JB, Knutton S. Enteropathogenic Escherichia coli virulence genes encoding secreted signalling proteins are essential for modulation of Caco-2 cell electrolyte transport. Infect. Immun. 1998;66:6049-53.

Donnenberg MS, Tacket CO, Losonsky G, Frankel G, Nataro JP, Dougan G, Levine MM. Effect of prior experimental human enteropathogenic Escherichia coli infection on illness following homologous and heterologous rechallenge. Infect. Immun. 1998;66:52-8.

Elliott SJ, Wainwright LA, McDaniel TK, Jarvis KG, Deng YK, Lai LC, McNamara BP, Donnenberg MS, Kaper JB. The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. Mol. Microbiol. 1998;28:1-4.

Eslava C, Navarro-Garcia F, Czeczulin JR, Henderson IR, Cravioto A, Nataro JP. Pet, an autotransporter enterotoxin from enteroaggregative Escherichia coli. Infect. Immun. 1998;66:3155-63.

Fernandez-Prada C, Tall BD, Elliott SE, Hoover DL, Nataro JP, Venkatesan MM. Hemolysin-positive enteroaggregative and cell-detaching Escherichia coli strains cause oncosis of human monocyte-derived macrophages and apoptosis of murine J774 cells. Infect. Immun. 1998;66:3918-24.

Frankel G, Phillips AD, Rosenshine I, Dougan G, Kaper JB, Knutton S. Enteropathogenic and enterohaemorrhagic Escherichia coli: more subversive elements. Mol. Microbiol. 1998;30:911-21.

Freedman DJ, Tacket CO, Delehanty A, Maneval DR, Nataro J, Crabb JH. Milk immunoglobulin with specific activity against purified colonization factor antigens can protect against oral challenge with enterotoxigenic Escherichia coli. J.Infect.Dis.1998;Mar;177:662-7.

Henderson IR, Navarro-Garcia F, Nataro JP. The great escape: structure and function of the autotransporter proteins. Trends.Microbiol.1998;6:370-8.

Hicks S, Frankel G, Kaper JB, Dougan G, Phillips AD. Role of intimin and bundle-forming pili in enteropathogenic Escherichia coli adhesion to pediatric intestinal tissue in vitro. Infect. Immun. 1998;66:1570-8.

Kaper JB. Enterohemorrhagic Escherichia coli. Curr.Opin.Microbiol.1998;1:103-108.

Kaper JB. EPEC delivers the goods. Trends. Microbiol. 1998;6:169-72.

Nataro JP, Kaper JB. Diarrheagenic Escherichia coli. Clin. Microbiol. Rev. 1998;11:142-201.

Nataro JP, Steiner T, Guerrant RL. Enteroaggregative Escherichia coli. Emerg. Infect. Dis. 1998;4:251-61.

Navarro-Garcia F, Eslava C, Villaseca JM, Lopez-Revilla R, Czeczulin JR, Srinivas S, Nataro JP, Cravioto A. In vitro effects of a high-molecular-weight heat-labile enterotoxin from enteroaggregative Escherichia coli. Infect. Immun. 1998;66:3149-54.

Neves BC, Knutton S, Trabulsi LR, Sperandio V, Kaper JB, Dougan G, Frankel G. Molecular and ultrastructural characterisation of EspA from different enteropathogenic Escherichia coli serotypes. FEMS Microbiol. Lett. 1998;169:73-80.

Perna NT, Mayhew GF, Posfai G, Elliott S, Donnenberg MS, Kaper JB, Blattner FR. Molecular evolution of a pathogenicity island from enterohemorrhagic Escherichia coli O157:H7. Infect. Immun. 1998;66:3810-7.

Sperandio V, Kaper JB, Bortolini MR, Neves BC, Keller R, Trabulsi LR. Characterization of the locus of enterocyte effacement (LEE) in different enteropathogenic Escherichia coli (EPEC) and Shiga-toxin producing Escherichia coli (STEC) serotypes. FEMS Microbiol. Lett. 1998;164:133-9.

Steiner TS, Lima AA, Nataro JP, Guerrant RL. Enteroaggregative Escherichia coli produce intestinal inflammation and growth impairment and cause interleukin-8 release from intestinal epithelial cells. J. Infect. Dis. 1998;177:88-96.

Wainwright LA, Kaper JB. EspB and EspD require a specific chaperone for proper secretion from enteropathogenic Escherichia coli. Mol. Microbiol. 1998;27:1247-60.

Wieler LH, Schwanitz A, Vieler E, Busse B, Steinruck H, Kaper JB, Baljer G. Virulence properties of Shiga toxin-producing Escherichia coli (STEC) strains of serogroup O118, a major group of STEC pathogens in calves. J. Clin. Microbiol. 1998;36:1604-7.

Czeczulin JR, Whittam TS, Henderson IR, Navarro-Garcia F, Nataro JP. Phylogenetic analysis of enteroaggregative and diffusely adherent Escherichia coli. Infect. Immun. 1999;67:2692-9.

Elias WP Jr, Czeczulin JR, Henderson IR, Trabulsi LR, Nataro JP. Organization of biogenesis genes for aggregative adherence fimbria II defines a virulence gene cluster in enteroaggregative Escherichia coli. J. Bacteriol. 1999;181:1779-85.

Elias WP, Suzart S, Trabulsi LR, Nataro JP, Gomes TA. Distribution of aggA and aafA gene sequences among Escherichia coli isolates with genotypic or phenotypic characteristics, or both, of enteroaggregative E. coli. J. Med Microbiol. 1999;48:597-9.

Elliott SJ, Hutcheson SW, Dubois MS, Mellies JL, Wainwright LA, Batchelor M, Frankel G, Knutton S, Kaper JB. Identification of CesT, a chaperone for the type III secretion of Tir in enteropathogenic Escherichia coli. Mol. Microbiol. 1999;33:1176-89.

Elliott SJ, Yu J, Kaper JB. The cloned locus of enterocyte effacement from enterohemorrhagic Escherichia coli O157:H7 is unable to confer the attaching and effacing phenotype upon E. coli K-12. Infect. Immun. 1999;67:4260-3.

Henderson IR, Hicks S, Navarro-Garcia F, Elias WP, Philips AD, Nataro JP. Involvement of the enteroaggregative Escherichia coli plasmid-encoded toxin in causing human intestinal damage. Infect. Immun. 1999;67:5338-44.

Mellies JL, Elliott SJ, Sperandio V, Donnenberg MS, Kaper JB. The Per regulon of enteropathogenic Escherichia coli: identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)-encoded regulator (Ler). Mol. Microbiol. 1999;33:296-306.

Navarro-Garcia F, Sears C, Eslava C, Cravioto A, Nataro JP. Cytoskeletal effects induced by pet, the serine protease enterotoxin of enteroaggregative Escherichia coli. Infect. Immun. 1999;67:2184-92.

Rios M, Prado V, Trucksis M, Arellano C, Borie C, Alexandre M, Fica A, Levine MM. Clonal diversity of Chilean isolates of enterohemorrhagic Escherichia coli from patients with hemolytic-uremic syndrome, asymptomatic subjects, animal reservoirs, and food products. J. Clin. Microbiol. 1999;37:778-81.

Sozhamannan S, Deng YK, Li M, Sulakvelidze A, Kaper JB, Johnson JA, Nair GB, Morris JG Jr. Gomez-Duarte OG, Ruiz-Tagle A, Gomez DC, Viboud GI, Jarvis KG, Kaper JB, Giron JA. Identification of lngA, the structural gene of longus type IV pilus of enterotoxigenic Escherichia coli. Microbiology. 1999;145:1809-16.

Sperandio V, Mellies JL, Nguyen W, Shin S, Kaper JB. Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 1999;96:15196-201.

Tacket CO, Losonsky G, Livio S, Edelman R, Crabb J, Freedman D. Lack of prophylactic efficacy of an enteric-coated bovine hyperimmune milk product against enterotoxigenic Escherichia coli challenge administered during a standard meal. J. Infect. Dis. 1999;180:2056-9.

Boedeker EC. Crohn's mucosa harbors adherent-invasive E. coli. Inflamm Bowel Dis. 2000, 6:155.

Elliott SJ, Sperandio V, Giron JA, Shin S, Mellies JL, Wainwright L, Hutcheson SW, McDaniel TK, Kaper JB. The locus of enterocyte effacement (LEE)-encoded regulator controls expression of both LEE- and non-LEE-encoded virulence factors in enteropathogenic and enterohemorrhagic Escherichia coli. Infect Immun. 2000, 68:6115-26.

Garcia MI, Jouve M, Nataro JP, Gounon P, Le Bouguenec C. Characterization of the AfaD-like family of invasins encoded by pathogenic Escherichia coli associated with intestinal and extra-intestin