Bookmark and Share

Publications - Biotechnology/Vaccine Development

Back to Publications List. 

Wyatt RG, Kapikian AZ, Greenberg HA, Kalica AR, Flores J, Hoshino Y, Chanock RM, Levine MM. Development of vaccines against rotavirus disease. Prog. Food Nutr. Sci. 1982;7:189-192.

Levine MM. Vaccines to prevent travelers’ diarrhea. Therapeutische Umschau. 1983;40:253-256.

Levine MM, Kaper JB, Lockman H, Black RE, Clements ML. Recombinant DNA risk assessment studies in man: efficacy of poorly-mobilized plasmids in biologic containment. J. Infec. Dis. 1983;148:699-709.

Levine MM, Kaper JB, Black RE, Clements ML. New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol. Rev. 1983;47:510-550.

Levine MM, Black RE, Clements ML, Kaper JB. Present status of cholera vaccines. Biochem. Soc. Trans. 1984;12:200-202.

Levine MM, Ferreccio C, Black RE, Chilean Typhoid Committee, Germanier R. New vaccines against typhoid fever. World Pediat. Child Care. 1987;3:115-126.

Levine MM, Tacket CO, Herrington DA, Losonsky GA, Murphy J, Ferreccio C. The current status of typhoid vaccine development and clinical trials with typhoid vaccines. SE Asian J. Trop. Med. Pub. Hlth. 1988;19:459-469.

Kaper JB, Tacket CO. Application of biotechnology to vaccine development. J. Indust. Microbiol. Supplement 3, 1988;29:109-118.

Kaper JB, Levine MM. Progress towards a vaccine against enterotoxigenic Escherichia coli. Vaccines. 1988;6:197-199.

Kaper JB. Vibrio cholerae Vaccines. Rev. Infect. Dis. Suppl. 3 1989;11:S568-S573.

Levine MM, Ferreccio C, Black RE, Tacket CO, Germanier R. Progress in Vaccines Against Typhoid Fever. Rev. Infect. Dis. 1988;2(S3):S552-S567.

Levine MM, Taylor DN, Ferreccio C. Typhoid vaccines come of age. Pediat. Infect. Dis. J. 1989;8:374-381.

Edelman, R. Conference Report. Oral Immunization Symposium. Vaccine 1989;7:166-167.

Levine MM, Edelman R. Future vaccines against enteric pathogens. Infect. Dis. Clin. North Amer. 1990;4:105-21.

Koenig MA, Khan MA, Wojtyniak B, Clemens JD, Chakraborty J, Fauveau V, Phillips JF, Akbar J, Barua US. Impact of measles vaccination on childhood mortality in rural Bangladesh. Bulletin of the World Health Organization 1990;68:441-447.

Levine MM. Vaccines against enteric infections. Lancet 1990;335:958-961.

Levine MM, Hone D, Heppner DG, Noriega F, Sriwathana B. Attenuated Salmonella as carriers for the expression of foreign antigens. Microecol. Ther. 1990;19:23-32.

Levine MM, Hone D, Tacket C, Ferreccio C, Cryz S. Clinical and field trials with attenuated Salmonella typhi as live oral vaccines and as "carrier" vaccines. Res. Microbiol. 1990;141:807-816.

Servos S, Chatfield S, Hone D, Levine MM, Dimitriadis G, Pickard D, Dougan G, Fairweather N, Charles I. Molecular cloning and characterization of the Aro D gene encoding 3-dehydroquinase from Salmonella typhi. J. Gen. Microbiol. 1990;137:147-152.

Edelman, R. Perspective on the development of vaccines against Lyme disease. Vaccine 1991;9:531-532.

Edelman R, Levine MM. Enteric vaccines. Maryland Med. J. 1991;40:199-203.

Levine MM. Vaccines and milk immunoglobulin concentrates for prevention of infectious diarrhea. J. Pediat. 1991;118:S129-S136.

Tacket CO and Levine MM. Vaccines against bacterial enteric infections. Annales Nestle 1991;49:124-130.

Levine, MM, Hone D, Tacket CO. Update on typhoid vaccines. Seminars in Pediatr. Infect. Dis. 1991;2:159-162.

Edelman R. An update on vaccine adjuvants in clinical trial. AIDS Res Human Retroviruses 1992;8:1409-1411.

Morris JG, Tacket CO, Levine MM. Oral carrier vaccines: new tricks in an old trade. (editorial comment) Gastroenterology 1992;103:699-702.

Edelman, R. Vaccines: New technologies and applications. A conference report. Vaccine 1993, 13:1361-1364.

Levine MM, Kaper JB. Live oral vaccines against cholera: An update. Vaccines 11:207-212 1993.

Levine MM, Noriega F. Vaccines to prevent bacterial enteric infections in children. Pediatr Ann 22:719-725, 1993.

Levine MM, Noriega F. Vaccines to prevent enteric infections. Bailliere’s Clinical Gastroenterology 7:501-17, 1993.

Ivanoff B, Levine MM, Lambert PH. Vaccination against typhoid fever: present status. Bull Wld Hlth Org 72:957-971, 1994.

Levine MM, Noriega F. Current status of vaccine development for enteric diseases. Semin Pediatr Infect Dis 5:243-250, 1994

Levine MM, Galen J, Barry E, Noriega F, Chatfield S, Dougan G, Tacket C. Attenuated Salmonella as live oral vaccines against typhoid fever and as live vectors. J Biotechnology 44:193-196, 1995.

Levine MM, Kaper JB. Live oral cholera vaccine: from principle to product. Bull Inst Pasteur 93: 243-353, 1995.

Levine MM, Noriega F. A review of the current status of enteric vaccines. Papua New Guinea Med. J. 1995 38:325-331.

Barry EM, Gomez-Duarte O, Chatfield S, Rappuoli R, Pizza M, Losonsky G, Galen J, Levine MM. Expression and immunogenicity of pertussis toxin S1 subunit-tetanus toxin fragment C fusions in Salmonella typhi vaccine strain CVD 908. Infect. Immun. 1996;64:4172-4181.

Levine MM. The legacy of Edward Jenner. Brit. Med. Jour. 1996;312:1177-1178.

Noriega FR, Losonsky G, Wang JY, Formal SB, Levine MM. Further characterization of )aroA )virG Shigella flexneri 2a strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector vaccine for delivering antigens of enterotoxigenic Escherichia coli. Infect. Immun. 1996;64:23-27

Galen JE, Gomez-Duarte OG, Losonsky GA, Halpern JL, Lauderbaugh CS, Kaintuck S, Reymann MK, Levine MM. A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens. Vaccine 1997;15:700-708.

Levine MM, Galen J, Barry E, Noriega F, Tacket C, Sztein M, Chatfield S, Dougan G, Losonsky G, Kotloff K. Attenuated Salmonella typhi and Shigella as live oral vaccines and as live vectors. Behring Inst. Mitt. 1997:120-123.

Levine MM, Levine OS. Influence of disease burden, public perception, and other factors on new vaccine development, implementation, and continued use. Lancet 1997;350:1386-1392.

Tacket CO, Kelly SM, Schodel F, Losonsky G, Nataro JP, Edelman R, Levine MM, Curtiss R 3rd. Safety and immunogenicity in humans of an attenuated Salmonella typhi vaccine vector strain expressing plasmid-encoded hepatitis B antigens stabilized by the Asd-balanced lethal vector system. Infect. Immun. 1997;65:3381-3385.

Levine MM. Experimental challenge studies in the development of vaccines for infectious diseases. Dev. Biol. Stand. 1998;95:169-74.

Levine MM, Dougan G. Optimism over vaccines administered via mucosal surfaces. Lancet 1998;351:1375-6.

Tacket CO, Mason HS, Losonsky G, Clements JD, Levine MM, Arntzen CJ. Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. Nature Med .1998;4:607-9.

Levine MM, Curran J. HIV vaccines and prevention in a world without Mary Lou Clements-Mann and Jonathan Mann. J. Hum Virol. 1999;2:58-60.

Peter G, des Vignes-Kendrick M, Eickhoff TC, Fine A, Galvin V, Levine MM, Maldonado YA, Marcuse EK, Monath TP, Osborn JE, Plotkin S, Poland GA, Quinlisk MP, Smith DR, Sokol M, Soland DB, Whitley-Williams PN, Williamson DE, Breiman RF. Lessons learned from a review of the development of selected vaccines. National Vaccine Advisory Committee. Pediatrics. 1999;104:942-50.

Taylor DN, Levine MM, Kuppens L, Ivanoff B. Why are typhoid vaccines not recommended for epidemic typhoid fever? J. Infect. Dis. 1999;180:2089-90.

Anderson RJ, Pasetti MF, Sztein MB, Levine MM, Noriega FR. DeltaguaBA attenuated Shigella flexneri 2a strain CVD 1204 as a Shigella vaccine and as a live mucosal delivery system for fragment C of tetanus toxin. Vaccine. 2000, 18:2193-202.

Rennels MB, Deloria MA, Pichichero ME, Losonsky GA, Englund JA, Meade BD, Anderson EL, Steinhoff MC, Edwards KM. Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines. Pediatrics. 2000, 105:e12.

Rennels MB, Englund JA, Bernstein DI, Losonsky GA, Anderson EL, Pichichero ME, Munoz FM, Wolff MC. Diminution of the anti-polyribosylribitol phosphate response to a combined diphtheria-tetanus-acellular pertussis/Haemophilus influenzae type b vaccine by concurrent inactivated poliovirus vaccination. Pediatr Infect Dis J. 2000, 19:417-23.

Tacket CO, Mason HS, Losonsky G, Estes MK, Levine MM, Arntzen CJ. Human immune responses to a novel Norwalk virus vaccine delivered in transgenic potatoes. J Infect Dis. 2000, 182:302-5.

Wu S, Beier M, Sztein MB, Galen J, Pickett T, Holder AA, Gomez-Duarte OG, Levine MM. Construction and immunogenicity in mice of attenuated Salmonella typhi expressing Plasmodium falciparum merozoite surface protein 1 (MSP-1) fused to tetanus toxin fragment C. J Biotechnol. 2000, 83:125-35.

Samandari T, Edelman R. Future nonenteric nonmalarial vaccines for travelers. In, "Vaccine Preventable Diseases." 2001. pp. 263-268.

Kotloff KL, Wasserman SS, Losonsky GA, Thomas, Jr. W, Nichols R, Edelman R, Bridwell M, Monath TP. Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults. Infection and Immunity. 2001, 69:988-995.

Altboum A, Barry EM, Losonsky G, Galen JE, Levine MM. Attenuated Shigella flexneri 2a delta guaBA strain CVD 1204 expressing enterotoxigenic Escherichia coli (ETEC) CS2 and CS3 fimbriae as a live mucosal vaccine against Shigella and ETEC infection. Infection & Immunity. 2001, 69:3150-3158.

Kotloff KL, Sztein MB, Wasserman SS, Losonsky GA, DiLorenzo SC, Walker RI. Safety and immunogenicity of oral inactivated whole-cell Helicobacter pylori vaccine with adjuvant among volunteers with or without subclinical infection. Infection & Immunity. 2001, 69:3581-3590.

Campbell JD, Levine MM. Vaccine against enteric bacterial pathogens. Asian Journal of Paediatric Practice. 2001, 5:19-37.

Edelman R. The development and use of vaccine adjuvants. In, "Molecular Biotechnology." 2002. pp. 129-148.

Frey SE, Couch RB, Tacket CO, Treanor JJ, Wolff M, Newman FK, Atmar RL, Edelman R, Nolan CM, Belshe RB. Clinical responses to undiluted and diluted smallpox vaccine. New England Journal of Medicine. 2002, 346:1265-1274.