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Santiago, Chile Facility

The Center’s relationship with the government, universities and health services of Santiago, Chile began in 1978, when Dr. Levine advised the Pan American Health Organization and Ministry of Health about controlling endemic typhoid fever. The Chile program, Centro para Vacunas en Desarrollo - Chile (CVD - Chile), has its headquarters in the Roberto del Rio Children’s Hospital. Collaborations in Santiago have included:

  • Field trials of Ty21a live oral typhoid vaccine involving 600,000 school children;

  • Establishment of a modern molecular diagnostic microbiology laboratory in the Microbiology Program, University of Chile Oriente Campus;

  • Quantification of the magnitude of the disease burden caused by Haemophilus influenzae type b (Hib) and Streptococcus pneumoniae;

  • Clinical trials with Hib conjugate vaccines, including a large-scale effectiveness trial;

  • Evaluations of combination infant vaccines;

  • Studies with a live intranasal influenza vaccine.