Publications - Parkinsons Disease
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Concentrations of tetrahyroisoquinolines in common fruits and vegetables. DeCuypere, M., Miller, D. and LeDoux, M. 21st Annual Symposium: Movement Disorders. [abstract]
Flotillin-1 in the substantia nigra of the Parkinson brain and a predominant localization in catecholaminergic nerves in the rat brain. Jackobowitz, D. and Kallarakal, A. Neurotoxicity Research 6: 245-258, 2004. [paper]
Gaucher disease: complexity in a "simple" disorder. Sidransky, E. Molecular Genetics and Metabolism 83: 6-15, 2004. [paper]
Genetic regulation of a-synuclein mRNA expression in various human brain tissues. Linnertz, C., Saucier, L., Ge, D., Cronin, K.D., Burke, J.R., Browndyke, J.N., Hulette, C.M., Wels-Bohmer, K.A., Chiba-Falek, O. PLoS ONE 4(10): e7480. [paper]
Glucocerebrosidase mutations in subjects with parkinsonism. Lwin, A., Orvisky, E., Goker-Alpan, O., LaMarca, M. and Sidransky, E. Molecular Genetics and Metabolism 81: 70-73, 2004. [paper]
Human brain derived neurotrophic factor (BDNF) gene, splicing patterns and assessments of associations with substance abuse and Parkinson's disease. Liu, Q., Walther, D., Drgon, T., Polesskay, O., Lesnick, T., Strain, K., Andrade, M., Bower, J., Maraganore, D., and Uhl, G. SFN, 2004. [abstract]
Iron, copper, and zinc distribution of the cerebellum. Popescu, B., Robinson, C., Rajput, A., Rajput, A., Harder, S. and Nichol, H. Cerebellum 8(2): 74-79, 2009. [paper]
LRRK2 in Lewy bodies of Parkinson's disease and dementia with Lewy bodies. Smith, M., Zhu, X., Babar, A., Siedlak, S., Yang, Q., Ito, G, Iwatsubo, T. and Perry, G. International conference on Alzheimer's Disease, 2006. [abstract]
LRRK2 in Parkinson's disease and dementia with Lewy bodies. Zhu, X., Babar, A., Siedlak, S., Yang, Q., Ito, G, Iwatsubo, T., Smith, M., Perry, G. and Chen, S. Molecular Neurodegeneration 1: 17, 2006. [paper]
LRRK2 is a component of Lewy bodies. Perry, G., Zhu, X., Babar, A., Siedlak, S., Yang, Q., Ito, G, Iwatsubo, T., Smith, M., and Chen, S. AD/PD 2007. [abstract]
Leucine-rich repeat kinase 2 colocalizes with a-synuclein in Parkinson's Disease, but non Tau-containing deposits in tauopathies. Perry, G., Zhu, X., Babar, A., Siedlak, S., Yang, Q., Ito, G., Iwatsubo, T., Smith, M. and Chen, S. Neurodegenerative Dis. 5: 222-224, 2008. [paper]
Leucine-rich repeat kinase 2 colocalizes with a-synuclein in Parkinson's Disease, but not Tau-containing deposits in taupathies. Perry, G., Zhu, X., Babar, A., Siedlak, S., Yang, Q., Ito, G., Iwatsubo, T., Smith, M. and Chen, S. Neurodegen. Dis. 5:222-224, 2008. [paper]
Levels of alpha-synuclein (SNCA)-RNA in sporadic parkinson disease patients. Chiba-Falek, O., Lopez, G. and Nussbaum. Mov. Disorder 21:1703-1708, 2006. [paper]
Localization of N-methyl-norsalsolinol within rodent and human brain. DeCuypere, M., Kalabokis, V., Hao, R., Schroeder, D., Miller, D and LeDoux, M. J. Neurosci. Res. 86: 2543-2552, 2008. [paper]
Mapping metals in Parkinson's and normal brain using rapid-scanning x-ray fluorescence. Popescu, B., George, M., Bergmann, U., Garachtchenko, A., Kelly, M., McCrea, R., Luning, K., Devon, R., George, G., Hanson, A, Harder, S., Chapman, D., Pickering, I. and Nichol, H. Phys Med Biol 54: 651-663, 2009. [paper]
Molecular genetic studies of different alcohol dehydrogenase classes in Parkinsons disease. Carmine, A.,Buervenich, S., Galter, D., Sydow, O., Anvret, M. and Olson, L Society of Neuroscience, 2001. [abstract]
Parkin facilitate the elimination of expanded polyglutamine proteins and leads to preservation of preteasome function. Tsai, Y., Fishman, P., Thakor, N., and Oyler, G. J. Biol. Chem. 278: 22044-22055, 2003. [paper]
Regional distribution of tetrahydroisoquinoline derivatives in rodent, human, and parkinson's disease brain. DeCuypere, M., Lu, Y., Miller, D. and LeDoux, M. J of Neurochem 107: 1398-1413, 2008. [paper]
Regulation of Parkin and PINK1 by neddylation. Choo, Y., Wang, D., Tao, A., Zhang, Z. SFN, 2009. [abstract]
Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease. Simon, D.K., Lin, M.T., Zheng, L., Liu, G., Ahn, C.H., Kim, L., Mauck, W.M., Twu, F., Flint Beal, M. and Johns, D.R. Neurobiology of Aging 25: 71-81, 2003. [paper]
Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. Zhang, Y., James, M., Middleton, F. and Davis, R. Amer. J. Medical Genetics Part B 137B: 5-16, 2005. [paper]